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This orthogroup contains 1,181 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,181 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 976 / 1,181 | 82.6% | 99.1% of 985 | ≥80% support |
| Pfam | PF00112 | Peptidase_C1 — Papain family cysteine protease | 983 / 1,181 | 83.2% | 96.6% of 1,018 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 985 / 1,181 | 83.4% | 99.5% of 990 | ≥80% support |
| GO | GO:0008234 Molecular Function | cysteine-type peptidase activity | 983 / 1,181 | 83.2% | 99.3% of 990 | ≥80% support |
| GO | GO:0004197 Molecular Function | cysteine-type endopeptidase activity | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0005764 Cellular Component | lysosome | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| GO | GO:0051603 Biological Process | proteolysis involved in protein catabolic process | 976 / 1,181 | 82.6% | 98.6% of 990 | ≥80% support |
| Pfam | PF08246 | Inhibitor_I29 — Cathepsin propeptide inhibitor domain (I29) | 911 / 1,181 | 77.1% | 89.5% of 1,018 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_001633385.1 | XP_001633385.1 | digestive cysteine proteinase 1 [Nematostella vectensis] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Nematostella vectensis | XP_032230875.2 | XP_048582926.1 | counting factor associated protein D isoform X1 [Nematostella vectensis] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Nematostella vectensis | XP_048582579.1 | XP_048582579.1 | LOW QUALITY PROTEIN: uncharacterized protein LOC5516076 [Nematostella vectensis] | P13277 Digestive cysteine proteinase 1 OS=Homarus americanus OX=670 | JBrowse |
| Nematostella vectensis | XP_048582580.1 | XP_048582580.1 | uncharacterized protein LOC5516093 [Nematostella vectensis] | Q86GF7 Crustapain OS=Pandalus borealis OX=6703 GN=Cys PE=1 SV=1 | JBrowse |
| Nematostella vectensis | XP_048582926.1 | XP_048582926.1 | counting factor associated protein D isoform X1 [Nematostella vectensis] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Nematostella vectensis | XP_048582927.1 | XP_048582926.1 | counting factor associated protein D isoform X1 [Nematostella vectensis] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Nematostella vectensis | XP_048582928.1 | XP_048582926.1 | counting factor associated protein D isoform X1 [Nematostella vectensis] | Q54TR1 Counting factor associated protein D OS=Dictyostelium discoi | JBrowse |
| Nematostella vectensis | XP_048583022.1 | XP_048583022.1 | counting factor associated protein D isoform X1 [Nematostella vectensis] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Nematostella vectensis | XP_048583024.1 | XP_048583024.1 | counting factor associated protein D isoform X2 [Nematostella vectensis] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Nematostella vectensis | XP_048583025.1 | XP_048583025.1 | pro-cathepsin H isoform X1 [Nematostella vectensis] | A0A1S4F2V5 Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV= | JBrowse |
| Nematostella vectensis | XP_048583026.1 | XP_048583026.1 | pro-cathepsin H isoform X2 [Nematostella vectensis] | Q26636 Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 SV=1 | JBrowse |
