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This orthogroup contains 1,064 genes from 115 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,064 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43788 | DNA2/NAM7 HELICASE FAMILY MEMBER | 552 / 1,064 | 51.9% | 60.6% of 911 | ≥50% support |
| Pfam | PF13087 | AAA_12 — AAA domain | 816 / 1,064 | 76.7% | 89.2% of 915 | ≥50% support |
| Pfam | PF13086 | AAA_11 — AAA domain | 803 / 1,064 | 75.5% | 87.8% of 915 | ≥50% support |
| Pfam | PF00773 | RNB | 602 / 1,064 | 56.6% | 65.8% of 915 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 803 / 1,064 | 75.5% | 85.4% of 940 | ≥50% support |
| GO | GO:0003723 Molecular Function | RNA binding | 605 / 1,064 | 56.9% | 64.4% of 940 | ≥50% support |
| GO | GO:0004540 Molecular Function | RNA nuclease activity | 602 / 1,064 | 56.6% | 64.0% of 940 | ≥50% support |
| GO | GO:0043139 Molecular Function | 5'-3' DNA helicase activity | 552 / 1,064 | 51.9% | 58.7% of 940 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_048588773.1 | XP_048588773.1 | helicase with zinc finger domain 2-like isoform X1 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588774.1 | XP_048588774.1 | helicase with zinc finger domain 2-like isoform X2 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588775.1 | XP_048588773.1 | helicase with zinc finger domain 2-like isoform X1 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588776.1 | XP_048588776.1 | helicase with zinc finger domain 2-like isoform X3 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588777.1 | XP_048588777.1 | helicase with zinc finger domain 2-like isoform X4 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588778.1 | XP_048588778.1 | helicase with zinc finger domain 2-like isoform X5 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588779.1 | XP_048588779.1 | helicase with zinc finger domain 2-like isoform X6 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588780.1 | XP_048588779.1 | helicase with zinc finger domain 2-like isoform X6 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588781.1 | XP_048588781.1 | helicase with zinc finger domain 2 isoform X1 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588782.1 | XP_048588781.1 | helicase with zinc finger domain 2 isoform X1 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588783.1 | XP_048588783.1 | helicase with zinc finger domain 2 isoform X3 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
| Nematostella vectensis | XP_048588784.1 | XP_048588783.1 | helicase with zinc finger domain 2 isoform X3 [Nematostella vectensis] | Q9BYK8 3'-5' exoribonuclease HELZ2 OS=Homo sapiens OX=9606 GN=HELZ2 | JBrowse |
