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This orthogroup contains 344 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 344 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10336 | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN | 264 / 344 | 76.7% | 93.3% of 283 | ≥50% support |
| Pfam | PF00017 | SH2 | 213 / 344 | 61.9% | 76.1% of 280 | ≥50% support |
| Pfam | PF00388 | PI-PLC-X — Phosphatidylinositol-specific phospholipase C, X domain | 201 / 344 | 58.4% | 71.8% of 280 | ≥50% support |
| Pfam | PF00168 | C2 | 184 / 344 | 53.5% | 65.7% of 280 | ≥50% support |
| Pfam | PF00387 | PI-PLC-Y — Phosphatidylinositol-specific phospholipase C, Y domain | 178 / 344 | 51.7% | 63.6% of 280 | ≥50% support |
| GO | GO:0004435 Molecular Function | phosphatidylinositol phospholipase C activity | 267 / 344 | 77.6% | 93.7% of 285 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 267 / 344 | 77.6% | 93.7% of 285 | ≥50% support |
| GO | GO:0048015 Biological Process | phosphatidylinositol-mediated signaling | 264 / 344 | 76.7% | 92.6% of 285 | ≥50% support |
| GO | GO:0051209 Biological Process | release of sequestered calcium ion into cytosol | 264 / 344 | 76.7% | 92.6% of 285 | ≥50% support |
| GO | GO:0010634 Biological Process | positive regulation of epithelial cell migration | 258 / 344 | 75.0% | 90.5% of 285 | ≥50% support |
| GO | GO:0006629 Biological Process | lipid metabolic process | 251 / 344 | 73.0% | 88.1% of 285 | ≥50% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 251 / 344 | 73.0% | 88.1% of 285 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 226 / 344 | 65.7% | 79.3% of 285 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 210 / 344 | 61.1% | 73.7% of 285 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_048577156.1 | XP_048577156.1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [Nematostella vectensis] | P10686 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga | JBrowse |
| Nematostella vectensis | XP_048577157.1 | XP_048577157.1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [Nematostella vectensis] | P10686 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga | JBrowse |
| Nematostella vectensis | XP_048577158.1 | XP_048577156.1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [Nematostella vectensis] | P10686 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga | JBrowse |
