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This orthogroup contains 331 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 331 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22780 | ADAPTIN, ALPHA/GAMMA/EPSILON | 259 / 331 | 78.3% | 99.6% of 260 | ≥50% support |
| Pfam | PF01602 | Adaptin_N — Adaptin N terminal region | 216 / 331 | 65.3% | 78.0% of 277 | ≥50% support |
| Pfam | PF14807 | AP4E_app_platf — Adaptin AP4 complex epsilon appendage platform | 195 / 331 | 58.9% | 70.4% of 277 | ≥50% support |
| GO | GO:0030124 Cellular Component | AP-4 adaptor complex | 259 / 331 | 78.3% | 100.0% of 259 | ≥50% support |
| GO | GO:0140312 Molecular Function | cargo adaptor activity | 259 / 331 | 78.3% | 100.0% of 259 | ≥50% support |
| GO | GO:0006886 Biological Process | intracellular protein transport | 216 / 331 | 65.3% | 83.4% of 259 | ≥50% support |
| GO | GO:0016192 Biological Process | vesicle-mediated transport | 216 / 331 | 65.3% | 83.4% of 259 | ≥50% support |
| GO | GO:0030117 Cellular Component | membrane coat | 216 / 331 | 65.3% | 83.4% of 259 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_001641922.2 | XP_001641922.2 | AP-4 complex subunit epsilon-1 isoform X2 [Nematostella vectensis] | Q9UPM8 AP-4 complex subunit epsilon-1 OS=Homo sapiens OX=9606 GN=AP | JBrowse |
| Nematostella vectensis | XP_032223449.1 | XP_032223449.1 | AP-4 complex subunit epsilon-1 isoform X1 [Nematostella vectensis] | Q9UPM8 AP-4 complex subunit epsilon-1 OS=Homo sapiens OX=9606 GN=AP | JBrowse |
