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This orthogroup contains 297 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 297 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR48106 | QUINONE OXIDOREDUCTASE PIG3-RELATED | 266 / 297 | 89.6% | 99.6% of 267 | ≥80% support |
| GO | GO:0016651 Molecular Function | oxidoreductase activity, acting on NAD(P)H | 266 / 297 | 89.6% | 99.6% of 267 | ≥80% support |
| GO | GO:0070402 Molecular Function | NADPH binding | 266 / 297 | 89.6% | 99.6% of 267 | ≥80% support |
| GO | GO:0003960 Molecular Function | NADPH:quinone reductase activity | 241 / 297 | 81.1% | 90.3% of 267 | ≥80% support |
| GO | GO:0048038 Molecular Function | quinone binding | 241 / 297 | 81.1% | 90.3% of 267 | ≥80% support |
| Pfam | PF00107 | ADH_zinc_N — Zinc-binding dehydrogenase | 237 / 297 | 79.8% | 88.1% of 269 | ≥50% support |
| Pfam | PF08240 | ADH_N — Alcohol dehydrogenase GroES-like domain | 214 / 297 | 72.1% | 79.6% of 269 | ≥50% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 235 / 297 | 79.1% | 88.0% of 267 | ≥50% support |
| KEGG | K10133 | TP53I3 — p53 signaling pathway | 160 / 297 | 53.9% | 92.5% of 173 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_001622806.2 | XP_001622806.2 | quinone oxidoreductase PIG3 isoform X2 [Nematostella vectensis] | Q53FA7 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I | JBrowse |
| Nematostella vectensis | XP_032225703.1 | XP_032225703.1 | quinone oxidoreductase PIG3 isoform X1 [Nematostella vectensis] | Q53FA7 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I | JBrowse |
