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This orthogroup contains 266 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 266 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13710 | DNA HELICASE RECQ FAMILY MEMBER | 207 / 266 | 77.8% | 95.4% of 217 | ≥50% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 190 / 266 | 71.4% | 81.9% of 232 | ≥50% support |
| Pfam | PF00270 | DEAD | 173 / 266 | 65.0% | 74.6% of 232 | ≥50% support |
| Pfam | PF00098 | zf-CCHC — Zinc knuckle | 159 / 266 | 59.8% | 68.5% of 232 | ≥50% support |
| GO | GO:0006310 Biological Process | DNA recombination | 207 / 266 | 77.8% | 88.8% of 233 | ≥50% support |
| GO | GO:0005694 Cellular Component | chromosome | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0006281 Biological Process | DNA repair | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0009378 Molecular Function | four-way junction helicase activity | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0043138 Molecular Function | 3'-5' DNA helicase activity | 206 / 266 | 77.4% | 88.4% of 233 | ≥50% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 204 / 266 | 76.7% | 87.6% of 233 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 204 / 266 | 76.7% | 87.6% of 233 | ≥50% support |
| GO | GO:0006268 Biological Process | DNA unwinding involved in DNA replication | 204 / 266 | 76.7% | 87.6% of 233 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 202 / 266 | 75.9% | 86.7% of 233 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 173 / 266 | 65.0% | 74.3% of 233 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 172 / 266 | 64.7% | 73.8% of 233 | ≥50% support |
| KEGG | K10730 | RECQL4 — DNA repair and recombination proteins | 169 / 266 | 63.5% | 96.6% of 175 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_032227814.1 | XP_032227814.1 | ATP-dependent DNA helicase Q4 [Nematostella vectensis] | Q75NR7 ATP-dependent DNA helicase Q4 OS=Mus musculus OX=10090 GN=Re | JBrowse |
