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This orthogroup contains 259 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 259 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45838 | HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER | 217 / 259 | 83.8% | 98.6% of 220 | ≥80% support |
| GO | GO:0042800 Molecular Function | histone H3K4 methyltransferase activity | 218 / 259 | 84.2% | 99.1% of 220 | ≥80% support |
| GO | GO:0051568 Biological Process | obsolete histone H3-K4 methylation | 218 / 259 | 84.2% | 99.1% of 220 | ≥80% support |
| GO | GO:0035097 Cellular Component | histone methyltransferase complex | 217 / 259 | 83.8% | 98.6% of 220 | ≥80% support |
| GO | GO:0045893 Biological Process | positive regulation of DNA-templated transcription | 217 / 259 | 83.8% | 98.6% of 220 | ≥80% support |
| Pfam | PF00856 | SET | 176 / 259 | 68.0% | 79.6% of 221 | ≥50% support |
| Pfam | PF05965 | FYRC — F/Y rich C-terminus | 174 / 259 | 67.2% | 78.7% of 221 | ≥50% support |
| Pfam | PF00628 | PHD | 172 / 259 | 66.4% | 77.8% of 221 | ≥50% support |
| Pfam | PF05964 | FYRN — F/Y-rich N-terminus | 168 / 259 | 64.9% | 76.0% of 221 | ≥50% support |
| Pfam | PF13771 | zf-HC5HC2H — PHD-like zinc-binding domain | 163 / 259 | 62.9% | 73.8% of 221 | ≥50% support |
| Pfam | PF02008 | zf-CXXC — CXXC zinc finger domain | 142 / 259 | 54.8% | 64.3% of 221 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 193 / 259 | 74.5% | 87.7% of 220 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 182 / 259 | 70.3% | 82.7% of 220 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 156 / 259 | 60.2% | 70.9% of 220 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 156 / 259 | 60.2% | 70.9% of 220 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_048588127.1 | XP_048588127.1 | histone-lysine N-methyltransferase 2A [Nematostella vectensis] | O08550 Histone-lysine N-methyltransferase 2B OS=Mus musculus OX=100 | JBrowse |
