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This orthogroup contains 247 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 247 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12710 | NUCLEAR PROTEIN LOCALIZATION 4 | 224 / 247 | 90.7% | 100.0% of 224 | ≥80% support |
| Pfam | PF05021 | NPL4 | 218 / 247 | 88.3% | 96.5% of 226 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 224 / 247 | 90.7% | 100.0% of 224 | ≥80% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 224 / 247 | 90.7% | 100.0% of 224 | ≥80% support |
| GO | GO:0031625 Molecular Function | ubiquitin protein ligase binding | 224 / 247 | 90.7% | 100.0% of 224 | ≥80% support |
| GO | GO:0043130 Molecular Function | ubiquitin binding | 224 / 247 | 90.7% | 100.0% of 224 | ≥80% support |
| Pfam | PF05020 | zf-NPL4 — NPL4 family, putative zinc binding region | 197 / 247 | 79.8% | 87.2% of 226 | ≥50% support |
| Pfam | PF11543 | UN_NPL4 — Nuclear pore localisation protein NPL4 | 168 / 247 | 68.0% | 74.3% of 226 | ≥50% support |
| KEGG | K14015 | NPLOC4, NPL4 — Ribosome biogenesis | 177 / 247 | 71.7% | 99.4% of 178 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_048576062.1 | XP_048576062.1 | nuclear protein localization protein 4 homolog isoform X1 [Nematostella vectensis] | Q8TAT6 Nuclear protein localization protein 4 homolog OS=Homo sapie | JBrowse |
| Nematostella vectensis | XP_048576063.1 | XP_048576063.1 | nuclear protein localization protein 4 homolog isoform X2 [Nematostella vectensis] | P60670 Nuclear protein localization protein 4 homolog OS=Mus muscul | JBrowse |
