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This orthogroup contains 242 genes from 134 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 242 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13856 | VHS DOMAIN CONTAINING PROTEIN FAMILY | 199 / 242 | 82.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0035091 Molecular Function | phosphatidylinositol binding | 200 / 242 | 82.6% | 100.0% of 200 | ≥80% support |
| GO | GO:0043130 Molecular Function | ubiquitin binding | 200 / 242 | 82.6% | 100.0% of 200 | ≥80% support |
| GO | GO:0005768 Cellular Component | endosome | 199 / 242 | 82.2% | 99.5% of 200 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 199 / 242 | 82.2% | 99.5% of 200 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 199 / 242 | 82.2% | 99.5% of 200 | ≥80% support |
| GO | GO:0030276 Molecular Function | clathrin binding | 199 / 242 | 82.2% | 99.5% of 200 | ≥80% support |
| Pfam | PF03127 | GAT | 187 / 242 | 77.3% | 94.4% of 198 | ≥50% support |
| Pfam | PF00790 | VHS | 177 / 242 | 73.1% | 89.4% of 198 | ≥50% support |
| KEGG | K26401 | TOM1, TOM1L1_2 — Membrane trafficking | 141 / 242 | 58.3% | 98.6% of 143 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_032240019.1 | XP_032240019.1 | TOM1-like protein 2 isoform X1 [Nematostella vectensis] | Q6ZVM7 TOM1-like protein 2 OS=Homo sapiens OX=9606 GN=TOM1L2 PE=1 S | JBrowse |
| Nematostella vectensis | XP_032240020.1 | XP_032240020.1 | TOM1-like protein 2 isoform X2 [Nematostella vectensis] | Q6ZVM7 TOM1-like protein 2 OS=Homo sapiens OX=9606 GN=TOM1L2 PE=1 S | JBrowse |
