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This orthogroup contains 237 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21451 | HISTONE H3 METHYLTRANSFERASE | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| Pfam | PF08123 | DOT1 | 192 / 237 | 81.0% | 100.0% of 192 | ≥80% support |
| GO | GO:0000077 Biological Process | DNA damage checkpoint signaling | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| GO | GO:0031151 Molecular Function | histone H3K79 methyltransferase activity | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| GO | GO:0051726 Biological Process | regulation of cell cycle | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| GO | GO:2000677 Biological Process | regulation of transcription regulatory region DNA binding | 195 / 237 | 82.3% | 100.0% of 195 | ≥80% support |
| KEGG | K11427 | DOT1L, DOT1 — Chromosome and associated proteins | 155 / 237 | 65.4% | 98.1% of 158 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Nematostella vectensis | XP_032243301.2 | XP_032243301.2 | histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [Nematostella vectensis] | Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS | JBrowse |
| Nematostella vectensis | XP_032243302.2 | XP_032243301.2 | histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [Nematostella vectensis] | Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS | JBrowse |
| Nematostella vectensis | XP_032243303.2 | XP_032243303.2 | histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2 [Nematostella vectensis] | Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS | JBrowse |
