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This orthogroup contains 229 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 229 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15321 | TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 | 168 / 229 | 73.4% | 98.8% of 170 | ≥50% support |
| Pfam | PF18428 | BRCT_3 — BRCA1 C Terminus (BRCT) domain | 151 / 229 | 65.9% | 88.3% of 171 | ≥50% support |
| Pfam | PF09038 | 53-BP1_Tudor — Tumour suppressor p53-binding protein-1 Tudor | 132 / 229 | 57.6% | 77.2% of 171 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 169 / 229 | 73.8% | 99.4% of 170 | ≥50% support |
| GO | GO:0000077 Biological Process | DNA damage checkpoint signaling | 168 / 229 | 73.4% | 98.8% of 170 | ≥50% support |
| GO | GO:0042393 Molecular Function | histone binding | 168 / 229 | 73.4% | 98.8% of 170 | ≥50% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 168 / 229 | 73.4% | 98.8% of 170 | ≥50% support |
| KEGG | K20915 | TP53BP1, P202 — NOD-like receptor signaling pathway | 141 / 229 | 61.6% | 99.3% of 142 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Pocillopora acuta | Pocillopora_acuta_HIv2___RNAseq.1718_t | RMX38506.1 | hypothetical protein pdam_00015225 [Pocillopora damicornis] | P70399 TP53-binding protein 1 OS=Mus musculus OX=10090 GN=Tp53bp1 P | JBrowse |
