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This orthogroup contains 337 genes from 127 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 337 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46006 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A | 299 / 337 | 88.7% | 99.7% of 300 | ≥80% support |
| Pfam | PF00621 | RhoGEF | 288 / 337 | 85.5% | 97.6% of 295 | ≥80% support |
| GO | GO:0035025 Biological Process | positive regulation of Rho protein signal transduction | 299 / 337 | 88.7% | 99.7% of 300 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 289 / 337 | 85.8% | 96.3% of 300 | ≥80% support |
| Pfam | PF00169 | PH | 205 / 337 | 60.8% | 69.5% of 295 | ≥50% support |
| KEGG | K20683 | ARHGEF3_8 — Membrane trafficking | 240 / 337 | 71.2% | 100.0% of 240 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| No member of this family matches the current filter. | |||||