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This orthogroup contains 231 genes from 105 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 231 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 207 / 231 | 89.6% | 100.0% of 207 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 213 / 231 | 92.2% | 100.0% of 213 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 213 / 231 | 92.2% | 100.0% of 213 | ≥80% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 213 / 231 | 92.2% | 100.0% of 213 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 207 / 231 | 89.6% | 97.2% of 213 | ≥80% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 207 / 231 | 89.6% | 97.2% of 213 | ≥80% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 175 / 231 | 75.8% | 82.2% of 213 | ≥50% support |
| Pfam | PF05192 | MutS_III — MutS domain III | 171 / 231 | 74.0% | 80.3% of 213 | ≥50% support |
| Pfam | PF05190 | MutS_IV — MutS family domain IV | 161 / 231 | 69.7% | 75.6% of 213 | ≥50% support |
| Pfam | PF05188 | MutS_II — MutS domain II | 160 / 231 | 69.3% | 75.1% of 213 | ≥50% support |
| Pfam | PF01624 | MutS_I — MutS domain I | 159 / 231 | 68.8% | 74.7% of 213 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 158 / 231 | 68.4% | 74.2% of 213 | ≥50% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 158 / 231 | 68.4% | 74.2% of 213 | ≥50% support |
| GO | GO:0043504 Biological Process | mitochondrial DNA repair | 158 / 231 | 68.4% | 74.2% of 213 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| No member of this family matches the current filter. | |||||
