Gene Family

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Member genes
5,156
Species
145
Sequences
5,156
Best annotation support
90.5%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.5% of the 5,156 members.

Support counts the member genes carrying the term. % of genes is that count over all 5,156 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNEL4668 / 5,15690.5%99.9%
of 4,674
≥80% support
PfamPF02931Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain4502 / 5,15687.3%95.2%
of 4,727
≥80% support
PfamPF02932Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region4371 / 5,15684.8%92.5%
of 4,727
≥80% support
GOGO:0016020
Cellular Component
membrane4779 / 5,15692.7%100.0%
of 4,779
≥80% support
GOGO:0006811
Biological Process
monoatomic ion transport4779 / 5,15692.7%100.0%
of 4,779
≥80% support
GOGO:0005216
Molecular Function
monoatomic ion channel activity4713 / 5,15691.4%98.6%
of 4,779
≥80% support
GOGO:0034220
Biological Process
monoatomic ion transmembrane transport4712 / 5,15691.4%98.6%
of 4,779
≥80% support
GOGO:0004888
Molecular Function
transmembrane signaling receptor activity4712 / 5,15691.4%98.6%
of 4,779
≥80% support
GOGO:0005887
Cellular Component
plasma membrane4669 / 5,15690.6%97.7%
of 4,779
≥80% support
GOGO:0007165
Biological Process
signal transduction4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0007268
Biological Process
chemical synaptic transmission4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0030594
Molecular Function
neurotransmitter receptor activity4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0042391
Biological Process
regulation of membrane potential4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0043005
Cellular Component
neuron projection4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0045202
Cellular Component
synapse4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0050877
Biological Process
nervous system process4668 / 5,15690.5%97.7%
of 4,779
≥80% support
GOGO:0005230
Molecular Function
extracellular ligand-gated monoatomic ion channel activity4537 / 5,15688.0%94.9%
of 4,779
≥80% support
GOGO:0005254
Molecular Function
chloride channel activity3382 / 5,15665.6%70.8%
of 4,779
≥50% support
GOGO:1902476
Biological Process
chloride transmembrane transport3382 / 5,15665.6%70.8%
of 4,779
≥50% support
GOGO:1904315
Molecular Function
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential3377 / 5,15665.5%70.7%
of 4,779
≥50% support
GOGO:0005231
Molecular Function
excitatory extracellular ligand-gated monoatomic ion channel activity3377 / 5,15665.5%70.7%
of 4,779
≥50% support
📊 Total members in OG0000070: 41 (filtered to PLUTE · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

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