Gene Family

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Member genes
2,372
Species
144
Sequences
2,372
Best annotation support
75.6%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 75.6% of the 2,372 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,372 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR13723ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE1793 / 2,37275.6%86.8%
of 2,065
≥50% support
PfamPF19030TSP1_ADAMTS — Thrombospondin type 1 domain1599 / 2,37267.4%74.4%
of 2,150
≥50% support
PfamPF00090TSP_1 — Thrombospondin type 1 domain1426 / 2,37260.1%66.3%
of 2,150
≥50% support
PfamPF17771ADAMTS_CR_2 — ADAMTS cysteine-rich domain 21411 / 2,37259.5%65.6%
of 2,150
≥50% support
PfamPF01562Pep_M12B_propep — Reprolysin family propeptide1357 / 2,37257.2%63.1%
of 2,150
≥50% support
GOGO:0004222
Molecular Function
metalloendopeptidase activity1889 / 2,37279.6%93.6%
of 2,018
≥50% support
GOGO:0006508
Biological Process
proteolysis1889 / 2,37279.6%93.6%
of 2,018
≥50% support
GOGO:0030198
Biological Process
extracellular matrix organization1829 / 2,37277.1%90.6%
of 2,018
≥50% support
GOGO:0031012
Cellular Component
extracellular matrix1785 / 2,37275.3%88.5%
of 2,018
≥50% support
GOGO:0008237
Molecular Function
metallopeptidase activity1585 / 2,37266.8%78.5%
of 2,018
≥50% support
📊 Total members in OG0000251: 17 (filtered to PLUTE · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

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