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This orthogroup contains 163 genes from 95 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 163 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00002 | 7tm_2 — 7 transmembrane receptor (Secretin family) | 135 / 163 | 82.8% | 90.0% of 150 | ≥80% support |
| GO | GO:0004930 Molecular Function | G protein-coupled receptor activity | 136 / 163 | 83.4% | 91.3% of 149 | ≥80% support |
| GO | GO:0007186 Biological Process | G protein-coupled receptor signaling pathway | 135 / 163 | 82.8% | 90.6% of 149 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 135 / 163 | 82.8% | 90.6% of 149 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 134 / 163 | 82.2% | 89.9% of 149 | ≥80% support |
| GO | GO:0007166 Biological Process | cell surface receptor signaling pathway | 134 / 163 | 82.2% | 89.9% of 149 | ≥80% support |
| PANTHER | PTHR24034 | EGF-LIKE DOMAIN-CONTAINING PROTEIN | 110 / 163 | 67.5% | 73.8% of 149 | ≥50% support |
| Pfam | PF12662 | cEGF — Complement Clr-like EGF-like | 123 / 163 | 75.5% | 82.0% of 150 | ≥50% support |
| Pfam | PF14670 | FXa_inhibition — Coagulation Factor Xa inhibitory site | 122 / 163 | 74.9% | 81.3% of 150 | ≥50% support |
| Pfam | PF07645 | EGF_CA — Calcium-binding EGF domain | 119 / 163 | 73.0% | 79.3% of 150 | ≥50% support |
| Pfam | PF16489 | GAIN | 98 / 163 | 60.1% | 65.3% of 150 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 126 / 163 | 77.3% | 84.6% of 149 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| No member of this family matches the current filter. | |||||
