Acropora microphthalma is a branching coral (family Acroporidae) distributed in Indo-Pacific reef environments, diagnostic for its minute radial corallites—a feature reflected in its specific epithet meaning 'small-eyed.' Its colonies inhabit shallow reef habitats and rely on Symbiodiniaceae photosymbiosis for nutrition. It was included in a multi-species Acropora genome sequencing study, providing comparative genomic data for understanding species boundaries and adaptive evolution within this diverse genus. Like all reef-building corals, it faces threats from ocean warming, acidification, and anthropogenic disturbance.