Sanderia malayensis is a scyphozoan jellyfish (family Pelagiidae) distributed in coastal waters of the Indo-Pacific, particularly in Southeast Asian seas, forming a moderate-sized medusa with eight marginal lappets and nematocyst-bearing tentacles capable of causing skin irritation. It is a pelagic predator feeding on zooplankton and small fish larvae in tropical coastal and estuarine environments. The species contributes to the diverse gelatinous zooplankton community of Southeast Asian coastal waters. Genomic data have been generated for this species and are available in public databases, enabling comparative studies of cnidarian evolution and ecology.