Gene detail

Detailed information of ENSDKPP00000037863.1 in Plumapathes pennacea

Genomic Location: chr7:16420503...16433621
NR annotation: RMX45403.1, hypothetical protein pdam_00000874 [Pocillopora damicornis]
Species Plumapathes pennacea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSDKPT00000037863

ATGAAGAGCGGCAAACAGTTTAGTCTGTCCCTCGCCAAGATGCAGAGGAAGAGGAAAAGACAAGATGACCATGGGGTACTGAGTAGTAACGAAAGTGACTGTAGTGAACAAAGTACTCAAAACAACATGCCAATCCCAGCTGTAGGTGATATTGTTGTACGTCCGAGGACAGCTGAGAACCGTGTTGAGAAGGAAGACATTTGTCATGGAAGGGAGACGTCGTCTGTTCTGACTTGTTCTTCACTTCATAATGTTTTGCCAAGGAAGCAAGGTTCGTTTGAGAAGCCTCGGAGCATCTTATCTTGGCTTAAACATTCGCCAAATCCATCCAAAACAGTCGCATGCCCAGTTTGTGAAAGGGCTGTGCATTTGCCCCATATAAACCGACATTTGGACAGTGGCTGTGACCTTTATGTTGTTAGCAAGGATTTATCTCGGGAAGCCAGTGTCAAGGAGGAGGAAAGCCATTATAACGAAGAGGAAAAAACTCAGATTAATTGTGAAGTTCCAAACCAACCTGATACAGAAAAAATGTTGACAGCCGATGTGACCACTAATGTCACAGAAGGTGTTGGTAATGCCAAAGGGAAGATCATTACCTCAAAAAGTGAGGGTAAAGAAAGTTATGGATGCAGCGATGCAAATTTTCCCAAAAATCATATTATAACCACACATCCCAGCACAGGGAAAACTGAAGATTCTTTTGAGGAGCAAATCTGTGGCCCTGTCAATGAACAAGAGGGAAACagtgagatggttgaaaatcCTGCAGAAAGAAGTGAAGCCATGAATCACCAGGAGCCCTATTATTTTGCTAATTTCAAGCTCGTTTTAAACACAGTTCTTGGAAACAGTGAAGACATAAAGCTGTTTAACTCTGATGACAACCACATCATCAACACCTTCAAGAATTTGTCTCAAGAAGGGCAGAAACTGTACATCCGCCTCTTTCAGCGAAATTGGGGTTGGTTTAGGTGTAGCAAACTGGATTATCAAGGAATTAGCCCAGATTTGAGGCCTGTAATCAGTCTTCTCAAAGAGAAAGGATTTCTGAAGGGAGAGGAAAATCTTACAGAGCTTGCAGACGTCCTAAGCCTTGTTCCTGCCCCTGAATTGAGGAACCTTGCGAAAGAGCTTCACATCACTCTGAAGTCTTCTCGTTGCAAGGGAGAGAACACAAAAGAATCACTGATGGGGTCATTAATTCACCATGGTAAAAAACAGAGGTCCCTGTTTGGCAACTCAGCTGGTGTTATATTGAAAAGAGCAAAACAGATGTTAGGTTCTTGTGTGAAAGTTTCCAAGGAATCAAGAGGTTTGTTTTCTCGCATCATTCTGCTTTTCACCATGAACATGATCCCAGACGATGATCACTCAACACAAGCTCAGGAGCTtggtttttcagtagattttcagtgcattttcagtggtttttcagtacattttcaatggattttcagtagattctCACTGGTTTTtctgtggtttttcagtgtattttcagtggatacttaCCTTTATCTTGTAAACAGCAAAAAGGTCGTGTACCCAGAATACACCATCTGCAGACCAAGCCCTGTGTTTCAAAACAGAGATGAGCTGTTGAGATTTTCAGCAGCTTCACAGGACAAACATGAAATGTTCACATCTTTTGAGAACAAAGACTTTGAGGTGGCTTTACAGTACTACCCCAAGGCTGCTGAGAACTTCAAGGAAATTCTTTCGGATTTGGAGAAGATCTCATCAAGCAAAACAAGTGCCAACCTTCCCATTCATCTGCGATGTTTCACAGCTGAGTTTGTGTACACCAAAATGTGTTATTTGGGTGTGGAAATTCTGCAGAAACAACGTCGATATGATGAAGCTGTAACTCAGCTAGAGTTGCTGTTAAGACAAAATGTTTTCTGTCAAGAATCTAGAGGCAAATGGTTTGATCGCCTGGCGTTGAACTTGCATCAACACCTGAAACAACCATCAAAGGCTCTGGAGGTCATCAAGAGAGGCTTGGTAGATCCTAATGTCCGTGCTGGACGCCGCCTGGCTTTAATGCAGAGAGCAAAACGTATTTTGACATCACCAGGGtatcagaagaaaaaaacagcAGAGGTTGAAGATTTTGGAGATCTGTCATTAGAGGAACCAAATGCTCCCAAAACTGTGACAATTTCTGGGAGAAGGTCAGCAGAGTTAGGAGTTTTCATTTCCAATGAAGTGGGCATGAATGGAGCAGATTTAGACTGCACCAAGACTTTCTGCTCTGTGGAAGAATTTGCCATGGCACACTACCGCCAACAAGGCTACAACCAAGGCATCCATGGCGAGGGTTCTACCTTTACAACCCTGTTTGGTTTACTCATGTGGGATGTTATTTTTGCTGATGGCATTCCTGATGTCTTCCGAGGTCCTTTTCAGTCTGCACCACTGGACATCTTCTCTGACTCATTTTATGAGACCCGCCAGTCACTTTTTGAAAAACGGCTGGAGACACTTCAGGCTGCATCTGCCAAACAACTTCAAGAATTGCTGGAGGAGTCGTGGTGTGAGCATGAAGGTCAGGTGTGTGTTGGAGTGAAATGGGATCGTTTTACAGGGATCAGCCAAGCTAAGCAACTGGTCTCCTGTTTTGGTGGCAAGTTCCTTGCAGGCGTGTTTGCGATTTTTGCCAAAAGCTATCGCTATCGATGCTCTGGCATTCCCGACCTCGTGGTTTGGAATCCATCCTCTTTGGAATACAAGATTGTCGAAGTCAAAGGTCCTGGCGACcgtttgtccacaaaacagcAGATCTGGTTAGATGAGCTGAGTTCGTTAGGCGCTCAAGCCGAAGTCTGCTATGTGACGGCTGTTGGAGCAAAACGGTTGAAAGTATCTTAA

Transcript

ENSDKPT00000037863

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q1LWH4	Fanconi-associated nuclease 1 OS=Danio rerio OX=7955 GN=fan1 PE=2 SV=2
Q69ZT1	Fanconi-associated nuclease 1 OS=Mus musculus OX=10090 GN=Fan1 PE=2 SV=2
Q9Y2M0	Fanconi-associated nuclease 1 OS=Homo sapiens OX=9606 GN=FAN1 PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004832 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08774 all species →	VRR_NUC	VRR-NUC domain	Domain	Interproscan
PF21315 all species →	FAN1_HTH	FAN1, HTH domain	Domain	Interproscan
PF21170 all species →	FAN1_TPR	Fanconi-associated nuclease 1, TPR domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014883 all species →	Domain	VRR-NUC domain	Interproscan
IPR033315 all species →	Family	Fanconi-associated nuclease 1-like	Interproscan
IPR049125 all species →	Domain	Fanconi-associated nuclease 1-like, winged-helix domain	Interproscan
IPR007110 all species →	Domain	Immunoglobulin-like domain	Interproscan
IPR006642 all species →	Domain	Rad18, zinc finger UBZ4-type	Interproscan
IPR011856 all species →	Homologous_superfamily	tRNA endonuclease-like domain superfamily	Interproscan
IPR049126 all species →	Domain	Fanconi-associated nuclease 1-like, TPR domain	Interproscan
IPR049132 all species →	Family	Fanconi-associated nuclease 1-like, eukaryotes	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR15749 all species →	FANCONI-ASSOCIATED NUCLEASE 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016788 all species →	Molecular Function	hydrolase activity, acting on ester bonds	Interproscan
GO:0004518 all species →	Molecular Function	nuclease activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0008409 all species →	Molecular Function	5'-3' exonuclease activity	Interproscan
GO:0017108 all species →	Molecular Function	5'-flap endonuclease activity	Interproscan
GO:0036297 all species →	Biological Process	interstrand cross-link repair	Interproscan
GO:0070336 all species →	Molecular Function	flap-structured DNA binding	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K15363	FAN1, MTMR15; fanconi-associated nuclease 1	EC:3.1.21.- EC:3.1.4.1	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Plumapathes pennacea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Plumapathes pennacea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →