Gene detail

Detailed information of ENSDKPP00000041389.1 in Plumapathes pennacea

Genomic Location: chr9:15975155...15986041
NR annotation: XP_027039833.1, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [Pocillopora damicornis]
Species Plumapathes pennacea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSDKPT00000041389

ATGTGGGAGTCCTTGAGCGCCAATTCTTTAATAAGTGTCGACTGCTTCTTGCCGACTGGTCTTTTAATCATTCTTAAACAAATCCAGATTGAATGTATGTTGTCAGACATAAAGAAGAGGTTGTGGATAGAAGCGAGCTGTTACCCTCTCTTTAATCTCCTCAAAGACCCATCCAGTTATGTCTTCGTTTGCATCAATCAAAAGGGAAGGCAGGAAGAACTGCTCGACGAATCTCAGTCACTTGCGGAGATCAGACCTCATCAGCCTTTACTGAAATTGATACAACGCAGAGGAGATCGAGACGAGAAGCTTTTTAAGTCTGGTTTGAGCGACCTTATCGGCAAGAATCTAAGTGACTTTGATGATATGGAGAGTGGCGAAGTTAAAGCATTTCGATGGCAATACCGTGAAGTCGTCGAAAATATCAACAATGAGCGAATGCAGCTGGACTGGAAAGAGCGGGCGATGTATGCTTACCCCCCAGAGCTTGCCTGCGAGCGAATTCCAGCTCATGTCCAAGCGAAACTGAGGGAAGGCGAACGGTTTGTCGTGTCTGTGGTGACAAAGGATACACAAGCATCAGAAAAGATGCATGCTTATATTGTCTCTGCCAGCTCTCTTCCTTCTGATTTGGTTTGCCAGGATTTGAAGAAGGATGCAATTGTGTCAGGTCTGCAGTCAGACCACTATGAGGAGCCGGATGATTATGTGATGAAGATAGTTGGCAGAGAGTGCTACCTCCTGGGAGAGTACCCTCTGCTCAGATACAAGTACATCCGCACATGTGTAGCCAAAGGTGATCGTCCACTCCTGAGGAGGGTACCTGTGTCATATCTGGAGCTAGAGCCAAAACAAGTGCTTTACTGCTATGATCATACTCCAGTCTTACCTCCAAGGAACTCTGAACACTGCTTGTCCTTATGGGATATCAAAACACACTTTAGGATCAAGGTTGTGTCTGCTGGTAATGTGAATGCAGGGGATGGGATGAAGGTTTGTGTCCACGGAGGTCTGTATCATGGTGAAGAAGCACTTTGCAATATTCCAAGTACCCTGTCATGTGATGGCCCAAATCCTTTCTGGAATGAATACCTTGACTTTGAGATACCTGTGTGTGATGCCCCTCGAATGGCCAGGGTGTGTTTTGTGATTTACGGAGTATCCGGGGAGCAGAAATCCAAGAGGAGGCGAAGACGAGCGAGGGAGGAATCCACCCCTCTTGCCTGGGTCAACACAACCCTGTTTGATCACAAAGATGAACTGTTGCAAGGTTATCATAAGTTGTTTGCTTGGCCAGTGCCAGATACCATGACGGACGTTGTGAATCCCATTGGTAGCGTCGTGTCCAATCCAAACATAACCAACTGTGTTTACCTGGAACTTGTTTTTCAGAGCTATTCACACCCTGTGAAATATCCTTCATACCCACAGATTTATGAATTAGCCACAGCAGCTGCCAAACAGGAAGAAGAGCAAGACTTTGGTCCGAAGCAAGGCGAACAACTCAAGCAGATTATTGACCGAGAACCACTGGTGCCAATTTTTGAGCAGGATAAAGAACTGCTCTGGTATTTCAGAAGAGAATGCTGCAAACGTTATTCATACTCACTGCCAAAACTTCTGTGTGCGGTCAAATGGAACAGCCGTGAGGATGTCGCACAGatgCAGATACTTCTTCAAACTTGGCCAAAGCTGGAGCCTGAACAAGCTCTGGAACTGCTGGACTACACGTATGCAGATCGTGAAGTCCGGAAATTTGCTGTTTGCTGTTTGGAGAAAATGAGCGACAGTGAACTCATGCAGTATTTGCTGCAGCTCGTCCAGGTGCTCAAGTATGAATGCTACCTGGACTGTGAATTGGCCCGGTTTCTTCTTAGGCGTGctctgaccaatcagagtgtcGGACACGCTTTCTTCTGGCTTCTCAGGGCTGAGATGGCCAATCCAGAAGTGTGCGTGAGGTTTGGTTTGATGCTAGAAGCCTACTGTCGCGGCTCACCCTCGCACTTCAAAAATCTGCAGAAACAGaaacaagCGGTGATCAAGATGAAGGCGATTACTGAACTTATTAAAAACGTTGACAGGGAAAAGTTCGAAGACGGTGTGAGAGTGATGAAGGAGTGTTTGAACCAAAGGTCATTCAAAAGGGCATTGTCAGAGATAACCTCGCCTCTAGACCCGAGTTACAAACTACGGATACCAATGGTCGAGAGATGCAAGTTTATGAAGTCAAAGAAGAGACCCCTGTGGCTGGAGTTTGAGAATTGGGACGATATGACGGATGATTTGGTCGCGTTCATATTCAAGAATGGAGACGATCTGAGACAGGACATGTTGTCTCTACAGCTTATCAAAATCATGGACAGGATTTGGCAAGATGAAGGGCTTGATTTGGGTATGACCCCATACGGCTGTCTGTGCACGGGACACGAAACAGGACTCATAGAAGTGGTGCGAAACGCTGAGACCATTGCCACCATACAGAGGGCGAAGCCAGGCAGCGTTTTCGATCAATTCTCCACGACATGCATACTGGACTGGCTGAAAGATCACAACCCAAGCGAAAAGTTGGAGGAAGCTGTGCGCCGGTTCACTCTCTCCTGTGCGGGGTACTGTGTGGCTACTTATGTCCTGGGGGTGGGGGACAGGCACAGTGATAATATTATGGTCTGCAAATCTGGCCAGTTACTCCATATCGACTTCGGTCACTTCCTTGGCAACGTGAAGAGTAAGTTCGGTATCCGCAGAGAGCGTGTGCCGTTCGTTCTGACGGAGCATTTCGTGCGCGTGATAACCAAAGGAGCAAGTCAAGGGCGAGCTGGGGCAACTGAAGAGTTCCAAGAATTTAGACGTCTTTGTGAGCGCGCTTTTCTGATCCTCCGTCGTCGAGGGCCTCTGTTCATCAACTTACTGGCCATGATGCTATCCGCTGGCATACCAGAACTGCGGTCGCTGGATGACATCGGTCACTTGCAGAAGACATTAGTGTTGTCTCTCCCTGAAGACGAGGCGCTCGAGCACTTTCGCCGGAAGTTAGACGAAGCTTTCAAGAACAGCTGGAAAACAAGTACTGACTGGTTTTTAAGAAAGTTTAAGCGGTAA

Transcript

ENSDKPT00000041389

CTGAAGGAAGTTCGACTTTCGTGTTGAAGTAATATACACCGCTGATTCGTGACACGCTTCATACCATGTGTAGTGGACCGCGTCGACTTAATCTCAAGCTTGACTGCAGCTTCATTTCGAGCGAAGGGACCAAGGTCGAGTTTCGAACCGAGTGTCGAACGGAGACGGAAATATCACTTCTGTTTTCCAATGCCGGCCCGTTGAAAAAAGCACATCAGCGGACTGACTCTGCCCGCCTTTACACAAGGTTGTTGACTTCAGCAGAAGGATGTGGGAGTCCTTGAGCGCCAATTCTTTAATAAGTGTCGACTGCTTCTTGCCGACTGGTCTTTTAATCATTCTTAAACAAATCCAGATTGAATGTATGTTGTCAGACATAAAGAAGAGGTTGTGGATAGAAGCGAGCTGTTACCCTCTCTTTAATCTCCTCAAAGACCCATCCAGTTATGTCTTCGTTTGCATCAATCAAAAGGGAAGGCAGGAAGAACTGCTCGACGAATCTCAGTCACTTGCGGAGATCAGACCTCATCAGCCTTTACTGAAATTGATACAACGCAGAGGAGATCGAGACGAGAAGCTTTTTAAGTCTGGTTTGAGCGACCTTATCGGCAAGAATCTAAGTGACTTTGATGATATGGAGAGTGGCGAAGTTAAAGCATTTCGATGGCAATACCGTGAAGTCGTCGAAAATATCAACAATGAGCGAATGCAGCTGGACTGGAAAGAGCGGGCGATGTATGCTTACCCCCCAGAGCTTGCCTGCGAGCGAATTCCAGCTCATGTCCAAGCGAAACTGAGGGAAGGCGAACGGTTTGTCGTGTCTGTGGTGACAAAGGATACACAAGCATCAGAAAAGATGCATGCTTATATTGTCTCTGCCAGCTCTCTTCCTTCTGATTTGGTTTGCCAGGATTTGAAGAAGGATGCAATTGTGTCAGGTCTGCAGTCAGACCACTATGAGGAGCCGGATGATTATGTGATGAAGATAGTTGGCAGAGAGTGCTACCTCCTGGGAGAGTACCCTCTGCTCAGATACAAGTACATCCGCACATGTGTAGCCAAAGGTGATCGTCCACTCCTGAGGAGGGTACCTGTGTCATATCTGGAGCTAGAGCCAAAACAAGTGCTTTACTGCTATGATCATACTCCAGTCTTACCTCCAAGGAACTCTGAACACTGCTTGTCCTTATGGGATATCAAAACACACTTTAGGATCAAGGTTGTGTCTGCTGGTAATGTGAATGCAGGGGATGGGATGAAGGTTTGTGTCCACGGAGGTCTGTATCATGGTGAAGAAGCACTTTGCAATATTCCAAGTACCCTGTCATGTGATGGCCCAAATCCTTTCTGGAATGAATACCTTGACTTTGAGATACCTGTGTGTGATGCCCCTCGAATGGCCAGGGTGTGTTTTGTGATTTACGGAGTATCCGGGGAGCAGAAATCCAAGAGGAGGCGAAGACGAGCGAGGGAGGAATCCACCCCTCTTGCCTGGGTCAACACAACCCTGTTTGATCACAAAGATGAACTGTTGCAAGGTTATCATAAGTTGTTTGCTTGGCCAGTGCCAGATACCATGACGGACGTTGTGAATCCCATTGGTAGCGTCGTGTCCAATCCAAACATAACCAACTGTGTTTACCTGGAACTTGTTTTTCAGAGCTATTCACACCCTGTGAAATATCCTTCATACCCACAGATTTATGAATTAGCCACAGCAGCTGCCAAACAGGAAGAAGAGCAAGACTTTGGTCCGAAGCAAGGCGAACAACTCAAGCAGATTATTGACCGAGAACCACTGGTGCCAATTTTTGAGCAGGATAAAGAACTGCTCTGGTATTTCAGAAGAGAATGCTGCAAACGTTATTCATACTCACTGCCAAAACTTCTGTGTGCGGTCAAATGGAACAGCCGTGAGGATGTCGCACAGatgCAGATACTTCTTCAAACTTGGCCAAAGCTGGAGCCTGAACAAGCTCTGGAACTGCTGGACTACACGTATGCAGATCGTGAAGTCCGGAAATTTGCTGTTTGCTGTTTGGAGAAAATGAGCGACAGTGAACTCATGCAGTATTTGCTGCAGCTCGTCCAGGTGCTCAAGTATGAATGCTACCTGGACTGTGAATTGGCCCGGTTTCTTCTTAGGCGTGctctgaccaatcagagtgtcGGACACGCTTTCTTCTGGCTTCTCAGGGCTGAGATGGCCAATCCAGAAGTGTGCGTGAGGTTTGGTTTGATGCTAGAAGCCTACTGTCGCGGCTCACCCTCGCACTTCAAAAATCTGCAGAAACAGaaacaagCGGTGATCAAGATGAAGGCGATTACTGAACTTATTAAAAACGTTGACAGGGAAAAGTTCGAAGACGGTGTGAGAGTGATGAAGGAGTGTTTGAACCAAAGGTCATTCAAAAGGGCATTGTCAGAGATAACCTCGCCTCTAGACCCGAGTTACAAACTACGGATACCAATGGTCGAGAGATGCAAGTTTATGAAGTCAAAGAAGAGACCCCTGTGGCTGGAGTTTGAGAATTGGGACGATATGACGGATGATTTGGTCGCGTTCATATTCAAGAATGGAGACGATCTGAGACAGGACATGTTGTCTCTACAGCTTATCAAAATCATGGACAGGATTTGGCAAGATGAAGGGCTTGATTTGGGTATGACCCCATACGGCTGTCTGTGCACGGGACACGAAACAGGACTCATAGAAGTGGTGCGAAACGCTGAGACCATTGCCACCATACAGAGGGCGAAGCCAGGCAGCGTTTTCGATCAATTCTCCACGACATGCATACTGGACTGGCTGAAAGATCACAACCCAAGCGAAAAGTTGGAGGAAGCTGTGCGCCGGTTCACTCTCTCCTGTGCGGGGTACTGTGTGGCTACTTATGTCCTGGGGGTGGGGGACAGGCACAGTGATAATATTATGGTCTGCAAATCTGGCCAGTTACTCCATATCGACTTCGGTCACTTCCTTGGCAACGTGAAGAGTAAGTTCGGTATCCGCAGAGAGCGTGTGCCGTTCGTTCTGACGGAGCATTTCGTGCGCGTGATAACCAAAGGAGCAAGTCAAGGGCGAGCTGGGGCAACTGAAGAGTTCCAAGAATTTAGACGTCTTTGTGAGCGCGCTTTTCTGATCCTCCGTCGTCGAGGGCCTCTGTTCATCAACTTACTGGCCATGATGCTATCCGCTGGCATACCAGAACTGCGGTCGCTGGATGACATCGGTCACTTGCAGAAGACATTAGTGTTGTCTCTCCCTGAAGACGAGGCGCTCGAGCACTTTCGCCGGAAGTTAGACGAAGCTTTCAAGAACAGCTGGAAAACAAGTACTGACTGGTTTTTAAGAAAGTTTAAGCGGTAATAATGACAGAACAATTCAAGTTGCTTCAGGTTTGGTAAGGAAAGGTAATCTTGCTACGGTACTGTACACTAAATTCCAGAATCTAAATCTCCCAACTAGAAATTgcaccgcggaaatacttTCTTTACGTCACTTCTGTTGGTcactcgaggtaaaatttcacatcgtttGCAAACcccgtttttcttgtttacaactTTGTTATATGTAAcaatgttatagaaaatgtattgaacaaacttatagttgagtattaggtcttagttttgaGTTTCTTAGCTACGTCTTGAACTTTAAAATCGGAAGTaattttcaagtgtaaacggcGCCTAAGTAAAACAATAAGCCTTTTGCATGATCACAGCAGGTCACATGACTTGAAGTTTAGCCTGATGCTTGAGTGTCAGAAATAGGCAgagaatttaacaaatatagaaATGCAAAACGTCGGCTCTTTTTGGCACTTCAAAGTTCGGAATTCTGAAGGGGAGTTAAATAGGAAAGTGACTTCTGACAATTTTATTTCGTATTTAAAATGTAAGACACAATGAATAATTTACCCAGTAGGGAAGATGAATAATCTCCACTAACAAATGCATATCAAGggttgcaagaaaaaaaaatgatgcGACACGAACGAAAAGGCCTACAAAGAGAATACGAAAGACATAGAGAGCCAAGAAGGGTATGTATAGTCATTGGAAATGCAGTGTGAGGTAACATctttaaatatttatttttatatttaataaatGAGTTCCCAGCATAACGTATGTCTTTCAGCTCAGAAGTTGTTCGTAGGTTATTCGTGTTGTGGAGCTCAATTAAGCGCAACTAGACACAGTTGTCCTCTGGCCACCCCCCACAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BTI9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Mus musculus OX=10090 GN=Pik3cb PE=1 SV=2
O00329	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform OS=Homo sapiens OX=9606 GN=PIK3CD PE=1 SV=2
O35904	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform OS=Mus musculus OX=10090 GN=Pik3cd PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001304 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00794 all species →	PI3K_rbd	PI3-kinase family, ras-binding domain	Domain	Interproscan
PF00454 all species →	PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	Family	Interproscan
PF00613 all species →	PI3Ka	Phosphoinositide 3-kinase family, accessory domain (PIK domain)	Repeat	Interproscan
PF00792 all species →	PI3K_C2	Phosphoinositide 3-kinase C2	Domain	Interproscan
PF02192 all species →	PI3K_p85B	PI3-kinase family, p85-binding domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000403 all species →	Domain	Phosphatidylinositol 3-/4-kinase, catalytic domain	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR001263 all species →	Domain	Phosphoinositide 3-kinase, accessory (PIK) domain	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR036940 all species →	Homologous_superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily	Interproscan
IPR000341 all species →	Domain	Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain	Interproscan
IPR003113 all species →	Domain	Phosphatidylinositol 3-kinase, adaptor-binding domain	Interproscan
IPR018936 all species →	Conserved_site	Phosphatidylinositol 3/4-kinase, conserved site	Interproscan
IPR042236 all species →	Homologous_superfamily	Phosphoinositide 3-kinase, accessory (PIK) domain superfamily	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR002420 all species →	Domain	C2 phosphatidylinositol 3-kinase-type domain	Interproscan
IPR015433 all species →	Family	Phosphatidylinositol kinase	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10048 all species →	PHOSPHATIDYLINOSITOL KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0005942 all species →	Cellular Component	phosphatidylinositol 3-kinase complex	Interproscan
GO:0014065 all species →	Biological Process	obsolete phosphatidylinositol 3-kinase signaling	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016303 all species →	Molecular Function	1-phosphatidylinositol-3-kinase activity	Interproscan
GO:0016477 all species →	Biological Process	cell migration	Interproscan
GO:0035005 all species →	Molecular Function	1-phosphatidylinositol-4-phosphate 3-kinase activity	Interproscan
GO:0036092 all species →	Biological Process	phosphatidylinositol-3-phosphate biosynthetic process	Interproscan
GO:0046854 all species →	Biological Process	phosphatidylinositol phosphate biosynthetic process	Interproscan
GO:0048015 all species →	Biological Process	phosphatidylinositol-mediated signaling	Interproscan
GO:0052742 all species →	Molecular Function	phosphatidylinositol kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00922	PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta	EC:2.7.1.153	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Plumapathes pennacea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Plumapathes pennacea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →