Gene detail

Detailed information of ENSJVNP00000017331.1 in Echinopora horrida

Genomic Location: chr16:23880034...23906693
NR annotation: XP_020630635.1, LOW QUALITY PROTEIN: rho-associated protein kinase 2-like [Orbicella faveolata]
Species Echinopora horrida · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSJVNT00000017461

ATGGAGGAACGAAAGAGGAGGGAAAATCTCGAGGGTTACGTCCGAAATCCTCGGAACGAACTATACATTGAAGGGCTTTTGGATGGCATCCAGTCTTTGGTGTGTGATTGTGACTTTCCAGCCCTCAGACGAAACAAGAACGTCGAGAACTTCTTACAGAGATATGAGAAGCCATGTAAAGTAATAGAAGAGTGTCGCATGAATGCCAAAGACTTTCAGATCGTAAAAGTCATAGGACGCGGTGCATTCGGCGAAGTTCAGTTGGTGAGGCACAAAGCATCGAAAAAAGTGTATGCTATGAAGCTTCTGAGCAAATTTGAGATGATCAAGAGATCTGATTCTGCATTCTTTTGGGAAGAGCGTGAAATTATGGCTCATACTACTAGTCCTTGGATCGTTAAGTTACACTTTGCTTTCcaagatgccaaaaatttatATATGGTGATGGACTATATGGCAGGAGGTGATTTGGTCAACCTTATGAGCAACTATGACATTCCTGAAAAGTGGGCTAAGTTCTATGGTGCTGAAGTGGTGCTAGCCCTTGATGCCATCCATTCAATGGGGTTTATTCACAgGGATGTGAAACCAGACAACATGCTTCTTGACAAGCAAGGCCATCTTAAGCTTGCAGACTTTGGGACTTGTATGAGAATGGACAAGGATGGTATGGTGAGATCAGATACAGCGGTTGGTACTCCTGATTATATTTCTCCTGAGGTTCTCAAGTCTCAGGGTGGTGAAGGCTACTATGGGCGTGAGTGTGATTGGTGGAGTGTAGGAGTGTTCTTGTATGAGTTACTTGTTGGAAAAATTATGGATCATAAAAATTCATTGCAGTTTCCTGATGACATTGAAATATCAAAGGATGCCAAGCATTTAATTTGTAGTTTTCTTACTGACAGAACTCAAAGAATTGGCCAAAGAGGGATAGCAGAGATTCAGAAGCATAGATTTTTTGTCAATGACCAGTGGGACTGGAACTCCATTAGAGATGCTGTTCCACCTGTGGTCCCTGAGCTTTCTAGTGACGATGATTACTCTCACTTTGATGACATACCTGAGCCAGACAGTGGAGAGGAGTTCTTCCCTACTCCAAAGGCTTTTGCTGGCAATCACCTACCTTTTATAGGATTTACGTTCTCAGAAGAAGTGGAATGGAATGTCTCACCAGGTGCGGGAGGTGCTGATGGAATGGTGAGGAGGGATGGAAATAGTTCCAATGGTGGAAATGATAGCCGATCTAAGCTGGAAGCTACCAACCGTAGACTGAGAGAATTAGAAGAACAAGTTGCTCTTGAAATGCAAGCTAAAGATGAGGTGGAACATAATTACAGAATGGTTAGCACAAAACTGGAAAAAGTCATGAAAGAATTGGACAATGAGTCTGAGGCAAAAAGAAGAGTAGAATCATCAAACAGAGAACTTGAAAGAAATGCAGCATTGTTTAAACATGATTTAAAAGAGGCTCAGAGGCGGTGTGAGTTTGAAGCTGAAGCCAAGAGAAAACTTGAAGGCAAAGTGCAGGAACTACAGAGCCGTCTTGATGCAGAACTTGATGCTCGGGACAGAATTTCACAGTCCTCACAGAGTGTCCAATCAAAGATTACTCAGTATGAGAAGCAGGTCTGGGAGTTGACGGAACAACTCAGAGTGGAAACAGATGCACACACTAAGGATAAAAAGTTACATAGTGATTTACAGAAGTCATACACAGTTATGGAGAGAACATATGGGGATTTACAAGACAAGAATAGGATCATTAGTGAACAGAAGCTTGGCTTAGAGAGAGAGCTTATCAAGGTCCAGGGAAATCTTGAAGCTGAAATGAACATGAGAAATCAAGCAAATAGTGCAAAAGTGGATATGGAATGTCAGAACAGACTCCTAAAAGATGAGCTTGAGCAGTTAAGGGCGAGATCTGCATCAGATGCCAGATTGCAACAAAAACTTCAACAGGATCTTATCAACTTAGAAAAAgCAAAGGCCAACACTGAGTATGAACTCAAGTCTGTCCagaataaatttgaaaaagttaCATTAGAGTATAAGGACTTCTGTTCTATGATTGAACTGTGTTACCAGACAGAAAAGAATAGGTTATCACTGACTCTGGAAGAGAGAACAGAACAAGAACGAGCTGAACAAAGCAAAACATTGGAAAGACTTGAGCAGGAATTGGTGATCAGAGAGAAGGCTGAGGCAGCAGCTGCCGAGGCTGAGAGAGAACGATCAGTTTTAGCTGTGGATCTTAAAGATCTACAACAGAAACTGGAGAGACTTAAACAAGAATATAATGCACTTCAAGACAAGaaTAAAAGTTTGAATACCAAGGTGGACTCTGAGAACCAGAGAAGAACACAACTAGAAAGTGACTTGAAAATGAACGCACAAGAAATAGCTGCACTGAGATCAACAGAGAAACAACTTGCCAAGCAAGTGGAAGATCTGATGGAAGAAAGAAAGCAGTTGGAAGATGCATTGTTATTCTTGCAGTTGACGTTTGGGTCGACGTTTACTCTGTACAAAACCCAAGTGAAAGAACTGAGAGAAGAAGTGGATGAAAAGGCAAAACAGGTGCAGGAGATGAGCAATGAAATACGACAGCTCAGCGAAGAGAGggaGTCTCTCTCTGCCCAACTGGAGCTGACATTGACAATGGTTGACTCAGAACAGCTGGCCAGGTCCATTGCTGAAGAACAATTCTCTGATCTGGAGAAAGAGAAGACTATGATTGAGCTGGAGGTCAAAGAATTAATTGCAAGGCATAAGAGTGACATGCTGGAAAAAGGCGCTCAGATTAGTCAGCTCGAAGAGCTTAACCAGCAGTTGACGGACAACTTGGATCAGAAAATGTCCGAAAAAGATGAACTTAACGGTAAAATCAAGGGCTTACAAGAAGAGCTCGGAAAGACCAAGGACAACAGTAAAGAGATCGAAGATGCTACAGAAAGCTTGAGGAAGCAGCTGTTTATCgagaaaacattaaaaacacAAGCTGTGAACAAACTGGCCGAGATCATGTGCAGGAAAGACTTCATGCAGAGAGAGAACAGTAAAAAAAGGAAGGCGACTTCCGATGACCTGAGGAAGAAGGAAAAAGAGTGTAGAAAACTACATCAAGAATTAGGAGCAGAACGAGAGAAGTATGGCCAGATGGTCACAAAATTCCAAGGGCAGATTGCTGAATACCAGCTAAATTTACAGATGGAGGTGGAGCACAGACAGAAAATGCAGATGGAACTGGATTCCAAAGACCTTATGATCGACAGACTGAACTCTCAAAATAAACAACGGAATCTGAATACGAGCATTAACGAAAACGACGAACTCACTGTTTCAGTCCATCTACCCAAGGAAGGTTGGGTATCAATACCCAACAAACAGAACATAAAAAAATATGGTTGGAAGAGACAATACTTAGTCGTTAGTAACCGGAAGATTTTCTTCTATAACTCGGATGCTGATCACCAAAGTACCTCAACTCCTTCCATCATTCTAGAAATTAGTAAGTTATACCACGTGAGATCTGTAACGCAAGGCGATGTCATACGTGCTGATGCTAAAGATATTCCTAGGATATTTCAGATTTTATATGCCAACGAGGCGGAGAGCATTAATCCAGTGGAAAAAGACAAAGAGGAACAACAACCAGAGGAACGAATGAACGCGATCGACTACATGAGGCATCAGTTTATTCCAATGCATTACCACATGCCAACCAACTGTGACTCGTGTAACAAACCCCTGTGGCACATGTTCAAACCTCCTCCAGCAGTCGAGTGCAAACGTTGTCATATGAAGTGTCACAAGGACCATGTGGACAGAGAAGAAGCTTGTATCACCATGTGTAATGTAAATATGGATATGATCTCAGCCAAGGAACTCTTGGTGCTCGCACAAACAGCTGATGAACAGAAGCAGTGGGTGTTGTACCTGAGCAAAAAAATCATTCGAAAAGAACCCAAAATAAAGAGCGCGTCCGTAAGATTAGGAGCTGAAGAAGCCAACTTGAGAAGAAATGTGGCGGACAGAAGCGCGGCCTCGAGACCGGGGGGACCTACGCGATCAGTGTCTGTCTCTTCAGGACAAAACAGAAAGATAACGTGA

Transcript

ENSJVNT00000017461

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O77819	Rho-associated protein kinase 1 OS=Oryctolagus cuniculus OX=9986 GN=ROCK1 PE=1 SV=1
P70335	Rho-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Rock1 PE=1 SV=1
O75116	Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002746 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF08912 all species →	Rho_Binding	Rho Binding	Coiled-coil	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR002219 all species →	Domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR015008 all species →	Domain	ROCK, Rho binding domain	Interproscan
IPR050839 all species →	Family	Rho-associated Serine/Threonine Kinase	Interproscan
IPR000961 all species →	Domain	AGC-kinase, C-terminal	Interproscan
IPR046349 all species →	Homologous_superfamily	C1-like domain superfamily	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22988 all species →	MYOTONIC DYSTROPHY S/T KINASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0031267 all species →	Molecular Function	small GTPase binding	Interproscan
GO:0000281 all species →	Biological Process	mitotic cytokinesis	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0007266 all species →	Biological Process	Rho protein signal transduction	Interproscan
GO:0018107 all species →	Biological Process	peptidyl-threonine phosphorylation	Interproscan
GO:0030866 all species →	Biological Process	cortical actin cytoskeleton organization	Interproscan
GO:0031032 all species →	Biological Process	actomyosin structure organization	Interproscan
GO:0048598 all species →	Biological Process	embryonic morphogenesis	Interproscan
GO:0072518 all species →	Molecular Function	Rho-dependent protein serine/threonine kinase activity	Interproscan
GO:1901888 all species →	Biological Process	regulation of cell junction assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSJVNP00000017331.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Echinopora horrida tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Echinopora horrida, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →