Genomic Location: chr2:2580418...2596349
NR annotation: XP_020600508.1, leukotriene A-4 hydrolase-like isoform X1 [Orbicella faveolata]
Species Echinopora horrida · all data for this species · gene families
| CDS |
| ENSJVNT00000024089 |
| Transcript |
| ENSJVNT00000024089 |
| Protein |
| ENSJVNP00000023924.1 |
| UniProt accession | Description |
|---|---|
| Q3SZH7 | Leukotriene A-4 hydrolase OS=Bos taurus OX=9913 GN=LTA4H PE=2 SV=3 |
| P30349 | Leukotriene A-4 hydrolase OS=Rattus norvegicus OX=10116 GN=Lta4h PE=1 SV=3 |
| P24527 | Leukotriene A-4 hydrolase OS=Mus musculus OX=10090 GN=Lta4h PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004401 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF09127 all species → | Leuk-A4-hydro_C | Leukotriene A4 hydrolase, C-terminal | Repeat | Interproscan |
| PF17900 all species → | Peptidase_M1_N | Peptidase M1 N-terminal domain | Domain | Interproscan |
| PF01433 all species → | Peptidase_M1 | Peptidase family M1 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015211 all species → | Domain | Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal | Interproscan |
| IPR045357 all species → | Domain | Aminopeptidase N-like , N-terminal domain | Interproscan |
| IPR001930 all species → | Family | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Interproscan |
| IPR042097 all species → | Homologous_superfamily | Aminopeptidase N-like , N-terminal domain superfamliy | Interproscan |
| IPR038502 all species → | Homologous_superfamily | Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily | Interproscan |
| IPR027268 all species → | Homologous_superfamily | Peptidase M4/M1, CTD superfamily | Interproscan |
| IPR034015 all species → | Family | Aminopeptidase, leukotriene A4 hydrolase-like | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR049980 all species → | Domain | Leukotriene A4 hydrolase-like, catalytic domain | Interproscan |
| IPR014782 all species → | Domain | Peptidase M1, membrane alanine aminopeptidase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45726 all species → | LEUKOTRIENE A-4 HYDROLASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0004177 all species → | Molecular Function | aminopeptidase activity | Interproscan |
| GO:0004301 all species → | Molecular Function | epoxide hydrolase activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0043171 all species → | Biological Process | peptide catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01254 | LTA4H; leukotriene-A4 hydrolase | EC:3.3.2.6 | Peptidases and inhibitors | ko01002 | deepkoala |
Genes whose expression across the transcriptome samples of Echinopora horrida tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Echinopora horrida, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
