Detailed information of HOLI00001.G53926 in Hydra oligactis

Genomic Location: HOLI00001:6285927...6287246
NR annotation: WP_095154186.1, MULTISPECIES: homoserine dehydrogenase [unclassified Pseudomonas]
Species Hydra oligactis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P29365Homoserine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=hom PE=3 SV=2
Q5F8J4Homoserine dehydrogenase OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) OX=242231 GN=NGO_0779 PE=1 SV=1
P37144Homoserine dehydrogenase OS=Methylobacillus glycogenes OX=406 GN=hom PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0025649 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF03447
all species →
NAD_binding_3Homoserine dehydrogenase, NAD binding domainDomainInterproscan
PF01842
all species →
ACTACT domainDomainInterproscan
PF00742
all species →
Homoserine_dhHomoserine dehydrogenaseDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036291
all species →
Homologous_superfamilyNAD(P)-binding domain superfamilyInterproscan
IPR016204
all species →
FamilyHomoserine dehydrogenaseInterproscan
IPR005106
all species →
DomainAspartate/homoserine dehydrogenase, NAD-bindingInterproscan
IPR045865
all species →
Homologous_superfamilyACT-like domainInterproscan
IPR002912
all species →
DomainACT domainInterproscan
IPR001342
all species →
DomainHomoserine dehydrogenase, catalyticInterproscan
IPR019811
all species →
Conserved_siteHomoserine dehydrogenase, conserved siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43331
all species →
HOMOSERINE DEHYDROGENASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004412
all species →
Molecular Functionhomoserine dehydrogenase activityInterproscan
GO:0009088
all species →
Biological Processthreonine biosynthetic processInterproscan
GO:0006520
all species →
Biological Processamino acid metabolic processInterproscan
GO:0016491
all species →
Molecular Functionoxidoreductase activityInterproscan
GO:0050661
all species →
Molecular FunctionNADP bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00003hom; homoserine dehydrogenaseEC:1.1.1.3
Lysine biosynthesisko00300deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Hydra oligactis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydra oligactis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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