Genomic Location: HOLI00059:874019...876606
NR annotation: WP_209396804.1, bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [Rhodoferax sp. AJA081-3]
Species Hydra oligactis · all data for this species · gene families
| CDS |
| HOLI00059.g26300.t1 |
| Transcript |
| HOLI00059.g26300.t1 |
| Protein |
| HOLI00059.G26300 |
| UniProt accession | Description |
|---|---|
| Q9I2V5 | Aconitate hydratase B OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=acnB PE=3 SV=1 |
| P36683 | Aconitate hydratase B OS=Escherichia coli (strain K12) OX=83333 GN=acnB PE=1 SV=3 |
| Q8ZRS8 | Aconitate hydratase B OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=acnB PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0022000 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00330 all species → | Aconitase | Aconitase family (aconitate hydratase) | Family | Interproscan |
| PF11791 all species → | Aconitase_B_N | Aconitate B N-terminal domain | Repeat | Interproscan |
| PF06434 all species → | Aconitase_2_N | Aconitate hydratase 2 N-terminus | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015932 all species → | Homologous_superfamily | Aconitase, domain 2 | Interproscan |
| IPR001030 all species → | Domain | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain | Interproscan |
| IPR015931 all species → | Homologous_superfamily | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 | Interproscan |
| IPR036008 all species → | Homologous_superfamily | Aconitase, iron-sulfur domain | Interproscan |
| IPR036288 all species → | Homologous_superfamily | Aconitase B, HEAT-like domain superfamily | Interproscan |
| IPR015933 all species → | Domain | Aconitase B, HEAT-like domain | Interproscan |
| IPR018136 all species → | Binding_site | Aconitase family, 4Fe-4S cluster binding site | Interproscan |
| IPR004406 all species → | Family | Aconitase B | Interproscan |
| IPR050926 all species → | Family | Aconitase/IPM Isomerase | Interproscan |
| IPR015929 all species → | Domain | Aconitase B, swivel | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43160 all species → | ACONITATE HYDRATASE B | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003994 all species → | Molecular Function | aconitate hydratase activity | Interproscan |
| GO:0006099 all species → | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0051539 all species → | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0019629 all species → | Biological Process | propionate catabolic process, 2-methylcitrate cycle | Interproscan |
| GO:0047456 all species → | Molecular Function | 2-methylisocitrate dehydratase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01682 | acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase | EC:4.2.1.3 EC:4.2.1.99 | Carbon fixation pathways in prokaryotes | ko00720 | deepkoala |
Genes whose expression across the transcriptome samples of Hydra oligactis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Hydra oligactis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
