Detailed information of HOLI02969.G47670 in Hydra oligactis

Genomic Location: HOLI02969:87039...88082
NR annotation: WP_252660848.1, phosphoribosylformylglycinamidine cyclo-ligase [Acidovorax kalamii]
Species Hydra oligactis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q126R8Phosphoribosylformylglycinamidine cyclo-ligase OS=Polaromonas sp. (strain JS666 / ATCC BAA-500) OX=296591 GN=purM PE=3 SV=1
Q21VH4Phosphoribosylformylglycinamidine cyclo-ligase OS=Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) OX=338969 GN=purM PE=3 SV=1
A9I602Phosphoribosylformylglycinamidine cyclo-ligase OS=Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) OX=340100 GN=purM PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002861 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02769
all species →		AIRS_CAIR synthase related protein, C-terminal domainDomainInterproscan
PF00586
all species →		AIRSAIR synthase related protein, N-terminal domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR010918
all species →		DomainPurM-like, C-terminal domainInterproscan
IPR004733
all species →		FamilyPhosphoribosylformylglycinamidine cyclo-ligaseInterproscan
IPR016188
all species →		DomainPurM-like, N-terminal domainInterproscan
IPR036676
all species →		Homologous_superfamilyPurM-like, C-terminal domain superfamilyInterproscan
IPR036921
all species →		Homologous_superfamilyPurM-like, N-terminal domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10520
all species →		TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004641
all species →		Molecular Functionphosphoribosylformylglycinamidine cyclo-ligase activityInterproscan
GO:0006189
all species →		Biological Process'de novo' IMP biosynthetic processInterproscan
GO:0004637
all species →		Molecular Functionphosphoribosylamine-glycine ligase activityInterproscan
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0006164
all species →		Biological Processpurine nucleotide biosynthetic processInterproscan
GO:0046084
all species →		Biological Processadenine biosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01933purM; phosphoribosylformylglycinamidine cyclo-ligaseEC:6.3.3.1
Purine metabolismko00230deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Hydra oligactis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydra oligactis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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