Detailed information of HSymV2.0_g05.08259_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_5:7614389...7620429
NR annotation: XP_002166734.2, akirin-2 [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q6GQB5Akirin-2 OS=Xenopus laevis OX=8355 GN=akirin2.S PE=1 SV=1
Q25C79Akirin-2 OS=Rattus norvegicus OX=10116 GN=Akirin2 PE=1 SV=1
B1AXD8Akirin-2 OS=Mus musculus OX=10090 GN=Akirin2 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0008616 (this species only) · gene tree & orthology

 Pfam domain
No Pfam domain signature was recorded for HSymV2.0_g05.08259_t1 in Hydractinia symbiolongicarpus.
 InterPro
InterPro termTypeDescriptionSource
IPR024132
all species →
FamilyAkirinInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR13293
all species →
UNCHARACTERIZEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000785
all species →
Cellular ComponentchromatinInterproscan
GO:0003712
all species →
Molecular Functiontranscription coregulator activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0045089
all species →
Biological Processpositive regulation of innate immune responseInterproscan
GO:0045944
all species →
Biological Processpositive regulation of transcription by RNA polymerase IIInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for HSymV2.0_g05.08259_t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g05.08259_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples
44TPM > 0
3Conditions
931.6Max TPM
556.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole embryo 36 36 501.05 924.79
Whole embryo · Triptolide 20 uM 4 4 782.14 931.65
Whole embryo · DMSO 0.5% 4 4 829.32 920.30

Per sample · hover a bar for the full sample record

Show the sample table (44 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR24482161 Whole embryo Whole embryo 7 hpf not recorded SRP436676 924.79
SRR24482162 Whole embryo Whole embryo 7 hpf not recorded SRP436676 886.65
SRR24482153 Whole embryo Whole embryo 7 hpf not recorded SRP436676 755.43
SRR24482163 Whole embryo Whole embryo 6 hpf not recorded SRP436676 685.44
SRR24482167 Whole embryo Whole embryo 3 hpf not recorded SRP436676 679.38
SRR24482165 Whole embryo Whole embryo 4 hpf not recorded SRP436676 676.84
SRR24482133 Whole embryo Whole embryo 6 hpf not recorded SRP436676 676.28
SRR24482166 Whole embryo Whole embryo 4 hpf not recorded SRP436676 664.20
SRR24482169 Whole embryo Whole embryo 2 hpf not recorded SRP436676 657.31
SRR24482176 Whole embryo Whole embryo 1 hpf not recorded SRP436676 632.21
SRR24482175 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 622.04
SRR24482170 Whole embryo Whole embryo 2 hpf not recorded SRP436676 615.77
SRR24482173 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 595.84
SRR24482171 Whole embryo Whole embryo 1 hpf not recorded SRP436676 589.55
SRR24482174 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 581.86
SRR24482168 Whole embryo Whole embryo 3 hpf not recorded SRP436676 572.38
SRR24482177 Whole embryo Whole embryo 1 hpf not recorded SRP436676 558.43
SRR24482137 Whole embryo Whole embryo 3 hpf not recorded SRP436676 505.88
SRR24482139 Whole embryo Whole embryo 2 hpf not recorded SRP436676 497.54
SRR24482135 Whole embryo Whole embryo 4 hpf not recorded SRP436676 487.39
SRR24482144 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 481.44
SRR24482143 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 450.62
SRR24482172 Whole embryo Whole embryo 30 mpf not recorded SRP436676 449.50
SRR24482134 Whole embryo Whole embryo 5 hpf not recorded SRP436676 405.48
SRR24482142 Whole embryo Whole embryo 30 mpf not recorded SRP436676 404.67
SRR24482140 Whole embryo Whole embryo 2 hpf not recorded SRP436676 403.30
SRR24482141 Whole embryo Whole embryo 1 hpf not recorded SRP436676 401.94
SRR24482138 Whole embryo Whole embryo 3 hpf not recorded SRP436676 389.20
SRR24482145 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 381.74
SRR24482136 Whole embryo Whole embryo 4 hpf not recorded SRP436676 362.87
SRR24482155 Whole embryo Whole embryo 72 hpf not recorded SRP436676 182.27
SRR24482159 Whole embryo Whole embryo 24 hpf not recorded SRP436676 180.38
SRR24482160 Whole embryo Whole embryo 24 hpf not recorded SRP436676 178.36
SRR24482157 Whole embryo Whole embryo 48 hpf not recorded SRP436676 171.84
SRR24482156 Whole embryo Whole embryo 72 hpf not recorded SRP436676 164.93
SRR24482158 Whole embryo Whole embryo 48 hpf not recorded SRP436676 164.07
SRR24482146 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 931.65
SRR24482147 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 870.19
SRR24482150 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 677.05
SRR24482149 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 649.68
SRR24482154 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 920.30
SRR24482148 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 908.13
SRR24482151 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 760.56
SRR24482152 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 728.31

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydractinia symbiolongicarpus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated37HSymV2.0_g11.19670_t10.981183234374587
Negatively correlated21HSymV2.0_g10.17584_t1-0.920989018287122

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydractinia symbiolongicarpus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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