Gene detail

Detailed information of HSymV2.0_g05.09853_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_5:34159528...34170470
NR annotation: XP_047129285.1, inositol polyphosphate 5-phosphatase OCRL [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

HSymV2.0_g05.09853_t1

ATGACTACGCAACTAAAAAAAGTTCAAAGCCTTCTTCGAAATGGCGAAACTTGCAAATATTGTCTTGAAGGCAGCCTGGTTTCTGGTTGGACCAGAACACCTCATCTTTTTGCAATTGTACGGTCTCAAGTAAATAACTATGGGTTACTTATTCTGTCACACCCTGGGATTGGTTCTAATGAAACCATTATTCGTCCAAAAAGTGCTATACCAATGGATGGAAACTTTCGATATCTCTTAAATAATAGTGGCACAAACTTCTCATCCTCAGATATTCAACTACAGCTCACATCAGGTTCAAATACATACACTGCTGAATTTGCATCTGGGTCTGCAATGCAAGATTTTATGTCAGTGTTAACGAGCATGTATAACGGTACGGGAATAAGCACGTCTTATGAATGGTTAAAAGCATATAATGGAGTTAATAATGACGCTGATAGTTCACAAGGGGAATGGCCGTGGAATGAAATAACAAAACCTTCAGTTGCAGATTATACACCTATCGCGTTTGATGCTGATGCAGATATTACCAATTTCGATCCACTCTCTTCTGCAAGTAAAAAGGATTGCAGTATTAAAGATGATTTATTAAAAGATTACGATGAAATTGTACCTAATACTAAATGTTTGAATATTAGTGGTACAAAAGAAAATAATTTATTAGAAGTCACACCAGTAAGAGTGACACCTACAAATGAACTGGATTTAAAAGATTTCGATCCTTTATCAAAAAAGGAGATAGAGGAAGGCATTAAAACAGAGAAAATGATATCAGCAGAACTTTTAAGAAGAAGCAGGGAAGTTGTTTCAACTCGTGCTTCTGCTGGCAAATCATGGCTTGAACGAACTTTGTCACAAAGCTCAGGTTCAACTGAAACAAAAGAAAGTGGTGGTCAAGAAGAGGCTTTCGATGTTGTTGATAATCTAGAGGTTCAGAATGTTCGTAACGAAAATACTGCCCCACCTCCTTATAAAGGCAATCTCTCAGGAAATGTTTTTAAGGGAATGCGTGCAAGAGAGAATTTTATTCGGTTGCATATGGCTGCAAGAGAAAAAGAATTTACTGAGCTATTTCCATTCACATTGCTTGCTGGTACATGGAATGTCAATGGCCAACTGGCTACTGAAAGTTTAGTTCCATGGCTACAAGATAATCCTGAATCACCAGATGTCATTGCAATCGGATTTCAAGAGCTTGACTTGAGTGCTGAAGCTTTAGTATTCAACGATTCAAGTCGAGAAGATACTTGGATGAAAGCTATTGAGAATGGTTTACCAAAAAATACAGATTATTTTAAGTTGAAACATGTTCGTCTTGTTGGTATGATGTTGGTTGTGTATGTTCAAACGAAACATAAGATGCAAGTATCTGATGTTGAGTCTGAAACATATGGGACTGGAATCATGGGCATGATGGGCAACAAGGGTGGTGTTGCTGTCAGATTTCAACTGCACAACTCAACAATCTGTTTTGTCAACTCCCACTTGGCAGCTCATTTAATGGAGTATGAGAGGCGTAACCAGGACTTCCGTGAAGTGTACAGTAAATTGAAGTTCTCTCTTTTCCAACCACCTATTGGAATATCACAACACAACATGGTGTTTTGGTTGGGTGATTTGAATTATCGTTTTGATGACCTGGACCCTGACCAAGTAAAAAATTTAGTCAGAAAAAACGATTTCGCAAAACTTTACAAGTATGACCAGCTTAACAGACAGCAAACTCAACAAAAAGCTTTCGATGGATTCAATGAGGGTAGCCTAACGTTTGCACCAACATATAAATATGATCCAGGGACAGACGATTGGGACACTAGTGAAAAGTCGCGTGCACCAGCTTGGTGTGATCGTGTGTTGTGGAAAGGAAAACAAATTGAACAGATAGCATACAGAAGTCATCCTCAGTTGAAATTAAGTGATCATAAACCCGTCAGTGCACTCTTCACTGTGGGAATCAAAGTTGTTGACCGAGCCAGGGAGCGTAAAGTATTTGAAGAAATTGTTCGAAAACTAGACAAACGTGAAAATGATTCGCTACCTCAAGTTAAGTTAGGCAAGCACGAATTTCAATTTGATATTGTGGAATTCATGGAAGAGAGGGTGGAGGTTTTACCTGTTGCAAATATTGGCCAGAGTCCAGTGGAATTTCAATTTATAGCAAAATTAGACGATGCTGACATTGCAAAACCTTGGTTTCGAGTTAATCCCTCTGCTGGATTTATAATGCCAGGAGATGTATTGGAAATCGAGTTGTCAGTAATGGTAGACAAGCTGTCGGCGCCCATGGTGACTGTAGGAAATTGCATTTTGGATGACATCTTAGTACTTCATCTTGTTGATGGAAAAGATTTCTTTGTACCCTTAAGTGGCGTATATACGCCCAGTGTGTTTGGTTCTTCTCTCGAAGCTTTAGTAAGAATATATGGTCCTATCAGACAGGTACCAATGGATTCTTTAATTCAATTGGAAAGTATAGCCTCCGTATTTGATTCAACTGATGGTGTATTTCCAGATTCCACGGAGCCTCTTGAAATACCGAAAGAACTGTGGTTGTTGATAGATCACTTATTTAAACACGGTATGACACAGGAGAATATTCTTCTGCAGTCTGGTATCGATGAAGAAATTCGTCAGATTCGGCATCACTTAGATACAGGGCAGGGTGGAGAAATTCCCGGGAGCATATTTTCTATTGGTGAAGCTTTGCTCTTATTTCTGGAAGCCCTTCCAGAACCTGTCATTCCATACAAATATCACACGAGATGCTTAGAAGCATGCAACAACTATGTCTTATGTAAACAGGTAGTAACACAACTTCCAGAGTGTCATGGCAACGTGTTTCGATACCTCACTGCATTTTTACGTGAGTTACTCAAGCAGAGCGCAGAAAACAAACTAGACGCCAAAATGCTTGCCACAGTGATGGGCTCCATCCTGTTGAGATCGCCGATGAACCAAAGCAAGAACTTGACCCGCAGAACGCAATCACAGATAGCTCAAAAGAAAGCGAAATTTGTCTTTCATTTCCTGGTAAATGACTTCAGAGGTTGA

Transcript

HSymV2.0_g05.09853_t1

ATTATGACTACGCAACTAAAAAAAGTTCAAAGCCTTCTTCGAAATGGCGAAACTTGCAAATATTGTCTTGAAGGCAGCCTGGTTTCTGGTTGGACCAGAACACCTCATCTTTTTGCAATTGTACGGTCTCAAGTAAATAACTATGGGTTACTTATTCTGTCACACCCTGGGATTGGTTCTAATGAAACCATTATTCGTCCAAAAAGTGCTATACCAATGGATGGAAACTTTCGATATCTCTTAAATAATAGTGGCACAAACTTCTCATCCTCAGATATTCAACTACAGCTCACATCAGGTTCAAATACATACACTGCTGAATTTGCATCTGGGTCTGCAATGCAAGATTTTATGTCAGTGTTAACGAGCATGTATAACGGTACGGGAATAAGCACGTCTTATGAATGGTTAAAAGCATATAATGGAGTTAATAATGACGCTGATAGTTCACAAGGGGAATGGCCGTGGAATGAAATAACAAAACCTTCAGTTGCAGATTATACACCTATCGCGTTTGATGCTGATGCAGATATTACCAATTTCGATCCACTCTCTTCTGCAAGTAAAAAGGATTGCAGTATTAAAGATGATTTATTAAAAGATTACGATGAAATTGTACCTAATACTAAATGTTTGAATATTAGTGGTACAAAAGAAAATAATTTATTAGAAGTCACACCAGTAAGAGTGACACCTACAAATGAACTGGATTTAAAAGATTTCGATCCTTTATCAAAAAAGGAGATAGAGGAAGGCATTAAAACAGAGAAAATGATATCAGCAGAACTTTTAAGAAGAAGCAGGGAAGTTGTTTCAACTCGTGCTTCTGCTGGCAAATCATGGCTTGAACGAACTTTGTCACAAAGCTCAGGTTCAACTGAAACAAAAGAAAGTGGTGGTCAAGAAGAGGCTTTCGATGTTGTTGATAATCTAGAGGTTCAGAATGTTCGTAACGAAAATACTGCCCCACCTCCTTATAAAGGCAATCTCTCAGGAAATGTTTTTAAGGGAATGCGTGCAAGAGAGAATTTTATTCGGTTGCATATGGCTGCAAGAGAAAAAGAATTTACTGAGCTATTTCCATTCACATTGCTTGCTGGTACATGGAATGTCAATGGCCAACTGGCTACTGAAAGTTTAGTTCCATGGCTACAAGATAATCCTGAATCACCAGATGTCATTGCAATCGGATTTCAAGAGCTTGACTTGAGTGCTGAAGCTTTAGTATTCAACGATTCAAGTCGAGAAGATACTTGGATGAAAGCTATTGAGAATGGTTTACCAAAAAATACAGATTATTTTAAGTTGAAACATGTTCGTCTTGTTGGTATGATGTTGGTTGTGTATGTTCAAACGAAACATAAGATGCAAGTATCTGATGTTGAGTCTGAAACATATGGGACTGGAATCATGGGCATGATGGGCAACAAGGGTGGTGTTGCTGTCAGATTTCAACTGCACAACTCAACAATCTGTTTTGTCAACTCCCACTTGGCAGCTCATTTAATGGAGTATGAGAGGCGTAACCAGGACTTCCGTGAAGTGTACAGTAAATTGAAGTTCTCTCTTTTCCAACCACCTATTGGAATATCACAACACAACATGGTGTTTTGGTTGGGTGATTTGAATTATCGTTTTGATGACCTGGACCCTGACCAAGTAAAAAATTTAGTCAGAAAAAACGATTTCGCAAAACTTTACAAGTATGACCAGCTTAACAGACAGCAAACTCAACAAAAAGCTTTCGATGGATTCAATGAGGGTAGCCTAACGTTTGCACCAACATATAAATATGATCCAGGGACAGACGATTGGGACACTAGTGAAAAGTCGCGTGCACCAGCTTGGTGTGATCGTGTGTTGTGGAAAGGAAAACAAATTGAACAGATAGCATACAGAAGTCATCCTCAGTTGAAATTAAGTGATCATAAACCCGTCAGTGCACTCTTCACTGTGGGAATCAAAGTTGTTGACCGAGCCAGGGAGCGTAAAGTATTTGAAGAAATTGTTCGAAAACTAGACAAACGTGAAAATGATTCGCTACCTCAAGTTAAGTTAGGCAAGCACGAATTTCAATTTGATATTGTGGAATTCATGGAAGAGAGGGTGGAGGTTTTACCTGTTGCAAATATTGGCCAGAGTCCAGTGGAATTTCAATTTATAGCAAAATTAGACGATGCTGACATTGCAAAACCTTGGTTTCGAGTTAATCCCTCTGCTGGATTTATAATGCCAGGAGATGTATTGGAAATCGAGTTGTCAGTAATGGTAGACAAGCTGTCGGCGCCCATGGTGACTGTAGGAAATTGCATTTTGGATGACATCTTAGTACTTCATCTTGTTGATGGAAAAGATTTCTTTGTACCCTTAAGTGGCGTATATACGCCCAGTGTGTTTGGTTCTTCTCTCGAAGCTTTAGTAAGAATATATGGTCCTATCAGACAGGTACCAATGGATTCTTTAATTCAATTGGAAAGTATAGCCTCCGTATTTGATTCAACTGATGGTGTATTTCCAGATTCCACGGAGCCTCTTGAAATACCGAAAGAACTGTGGTTGTTGATAGATCACTTATTTAAACACGGTATGACACAGGAGAATATTCTTCTGCAGTCTGGTATCGATGAAGAAATTCGTCAGATTCGGCATCACTTAGATACAGGGCAGGGTGGAGAAATTCCCGGGAGCATATTTTCTATTGGTGAAGCTTTGCTCTTATTTCTGGAAGCCCTTCCAGAACCTGTCATTCCATACAAATATCACACGAGATGCTTAGAAGCATGCAACAACTATGTCTTATGTAAACAGGTAGTAACACAACTTCCAGAGTGTCATGGCAACGTGTTTCGATACCTCACTGCATTTTTACGTGAGTTACTCAAGCAGAGCGCAGAAAACAAACTAGACGCCAAAATGCTTGCCACAGTGATGGGCTCCATCCTGTTGAGATCGCCGATGAACCAAAGCAAGAACTTGACCCGCAGAACGCAATCACAGATAGCTCAAAAGAAAGCGAAATTTGTCTTTCATTTCCTGGTAAATGACTTCAGAGGTTGAGCTCGGAGATGTCATATTCAAGGgagagagagagagagagagagagagagagagagTACGCGACAGGCTTGTAACAGCTGCTCAGATAAGTTGCTGTGGTGAGGCTGTGTCTAATAATGTTTACTGCCAGCCTGTTTTGAGCACTTAAGTGAAATCCAAATGGTGTTATCCATGCATTGCATTGATTTAAAAAATAAACAAACATTTTTTACTGTTTCACGTTTTATCCCACCTGATATTTTATTTATAGATTGCTTTTTAATTCCATATCCCAATAATTCTTTTATTTTCGCGTGTATTTTAAATTGGTTGCTTTCTTCTTAACGTTAAGAACATGGCGACACATTTTGCTCAACTTTTAACATTTTTTGAAGCAATATGTATATAGATATTCAGCGTACGTTTAATTTGTATTTATTTTTTTACTAAATAGATATTAAGACAACTTGGAAGTCAACTCATGTATGTCTTCGTTTCCAAGGCCTGTGGTTTGTACTggctaatgtataaaaaaatagtcggtggtcgtggaaaaatcaatgggttcacccgttctttttataccacattgcgtg

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
D3ZGS3	Inositol polyphosphate 5-phosphatase OCRL OS=Rattus norvegicus OX=10116 GN=Ocrl PE=1 SV=1
Q6NVF0	Inositol polyphosphate 5-phosphatase OCRL OS=Mus musculus OX=10090 GN=Ocrl PE=1 SV=1
P32019	Type II inositol 1,4,5-trisphosphate 5-phosphatase OS=Homo sapiens OX=9606 GN=INPP5B PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003517 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16776 all species →	INPP5B_PH	Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain	Domain	Interproscan
PF21310 all species →	OCRL-like_ASH	Inositol polyphosphate 5-phosphatase OCRL-like, ASH domain	Domain	Interproscan
PF00620 all species →	RhoGAP	RhoGAP domain	Domain	Interproscan
PF03372 all species →	Exo_endo_phos	Endonuclease/Exonuclease/phosphatase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036691 all species →	Homologous_superfamily	Endonuclease/exonuclease/phosphatase superfamily	Interproscan
IPR013783 all species →	Homologous_superfamily	Immunoglobulin-like fold	Interproscan
IPR046985 all species →	Family	Inositol 5-phosphatase	Interproscan
IPR008936 all species →	Homologous_superfamily	Rho GTPase activation protein	Interproscan
IPR031896 all species →	Domain	INPP5B, PH domain	Interproscan
IPR047078 all species →	Domain	Inositol polyphosphate 5-phosphatase OCRL, RhoGAP	Interproscan
IPR000198 all species →	Domain	Rho GTPase-activating protein domain	Interproscan
IPR000300 all species →	Domain	Inositol polyphosphate-related phosphatase	Interproscan
IPR048869 all species →	Domain	OCRL-1/2, ASH domain	Interproscan
IPR037793 all species →	Domain	OCRL1/INPP5B, INPP5c domain	Interproscan
IPR005135 all species →	Domain	Endonuclease/exonuclease/phosphatase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11200 all species →	INOSITOL 5-PHOSPHATASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004439 all species →	Molecular Function	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Interproscan
GO:0046856 all species →	Biological Process	phosphatidylinositol dephosphorylation	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0016791 all species →	Molecular Function	phosphatase activity	Interproscan
GO:0052745 all species →	Molecular Function	inositol phosphate phosphatase activity	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01099	INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F	EC:3.1.3.36	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g05.09853_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples

44TPM > 0

3Conditions

86.1Max TPM

57.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole embryo	36	36	54.23	71.31
Whole embryo · Triptolide 20 uM	4	4	76.95	86.10
Whole embryo · DMSO 0.5%	4	4	66.06	72.89

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR24482167	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	71.31
SRR24482161	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	69.56
SRR24482165	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	68.67
SRR24482169	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	68.52
SRR24482142	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	68.14
SRR24482166	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	67.29
SRR24482141	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	67.29
SRR24482168	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	66.56
SRR24482133	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	64.58
SRR24482140	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	62.30
SRR24482135	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	62.24
SRR24482170	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	61.63
SRR24482145	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	61.55
SRR24482139	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	61.16
SRR24482134	Whole embryo	Whole embryo	5 hpf	not recorded	SRP436676	61.06
SRR24482136	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	60.47
SRR24482143	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	60.20
SRR24482171	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	59.38
SRR24482174	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	59.17
SRR24482138	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	59.11
SRR24482144	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	58.17
SRR24482163	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	57.63
SRR24482153	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	57.54
SRR24482172	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	57.44
SRR24482162	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	57.35
SRR24482175	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	57.01
SRR24482173	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	55.79
SRR24482137	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	51.98
SRR24482176	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	50.48
SRR24482177	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	41.20
SRR24482160	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	30.02
SRR24482159	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	29.17
SRR24482157	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	22.78
SRR24482156	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	16.33
SRR24482158	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	14.89
SRR24482155	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	14.41
SRR24482146	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	86.10
SRR24482147	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	81.20
SRR24482150	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	74.27
SRR24482149	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	66.23
SRR24482154	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	72.89
SRR24482151	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	67.45
SRR24482152	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	64.30
SRR24482148	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	59.59

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.