Detailed information of HSymV2.0_g06.10246_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_6:11954980...11962461
NR annotation: XP_002157298.1, 60S ribosomal protein L19 [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P36241Large ribosomal subunit protein eL19 OS=Drosophila melanogaster OX=7227 GN=RpL19 PE=1 SV=2
Q7ZYS1Large ribosomal subunit protein eL19 OS=Xenopus laevis OX=8355 GN=rpl19 PE=1 SV=1
Q90YU8Large ribosomal subunit protein eL19 OS=Ictalurus punctatus OX=7998 GN=rpl19 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0007487 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01280
all species →		Ribosomal_L19eRibosomal protein L19eFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000196
all species →		DomainLarge ribosomal subunit protein eL19 domainInterproscan
IPR023638
all species →		Conserved_siteLarge ribosomal subunit protein eL19, conserved siteInterproscan
IPR035970
all species →		Homologous_superfamilyLarge ribosomal subunit protein eL19 superfamilyInterproscan
IPR033935
all species →		DomainLarge ribosomal subunit protein eL19, eukaryoticInterproscan
IPR039547
all species →		FamilyLarge ribosomal subunit protein eL19Interproscan
IPR015972
all species →		Homologous_superfamilyLarge ribosomal subunit protein eL19, domain 1Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10722
all species →		60S RIBOSOMAL PROTEIN L19Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003735
all species →		Molecular Functionstructural constituent of ribosomeInterproscan
GO:0005840
all species →		Cellular ComponentribosomeInterproscan
GO:0006412
all species →		Biological ProcesstranslationInterproscan
GO:0022625
all species →		Cellular Componentcytosolic large ribosomal subunitInterproscan
GO:0003723
all species →		Molecular FunctionRNA bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K02885RP-L19e, RPL19; large subunit ribosomal protein L19e-Ribosomeko03011deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g06.10246_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples
44TPM > 0
3Conditions
2,912.8Max TPM
765.7Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole embryo 36 36 790.20 2,912.78
Whole embryo · Triptolide 20 uM 4 4 601.66 767.61
Whole embryo · DMSO 0.5% 4 4 709.65 889.23

Per sample · hover a bar for the full sample record

Show the sample table (44 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR24482158 Whole embryo Whole embryo 48 hpf not recorded SRP436676 2,912.78
SRR24482157 Whole embryo Whole embryo 48 hpf not recorded SRP436676 2,353.98
SRR24482156 Whole embryo Whole embryo 72 hpf not recorded SRP436676 2,295.33
SRR24482159 Whole embryo Whole embryo 24 hpf not recorded SRP436676 2,252.26
SRR24482155 Whole embryo Whole embryo 72 hpf not recorded SRP436676 2,073.15
SRR24482160 Whole embryo Whole embryo 24 hpf not recorded SRP436676 1,816.80
SRR24482161 Whole embryo Whole embryo 7 hpf not recorded SRP436676 854.64
SRR24482162 Whole embryo Whole embryo 7 hpf not recorded SRP436676 823.19
SRR24482163 Whole embryo Whole embryo 6 hpf not recorded SRP436676 780.72
SRR24482153 Whole embryo Whole embryo 7 hpf not recorded SRP436676 632.93
SRR24482166 Whole embryo Whole embryo 4 hpf not recorded SRP436676 579.71
SRR24482176 Whole embryo Whole embryo 1 hpf not recorded SRP436676 579.48
SRR24482177 Whole embryo Whole embryo 1 hpf not recorded SRP436676 578.07
SRR24482168 Whole embryo Whole embryo 3 hpf not recorded SRP436676 577.09
SRR24482170 Whole embryo Whole embryo 2 hpf not recorded SRP436676 550.17
SRR24482169 Whole embryo Whole embryo 2 hpf not recorded SRP436676 533.74
SRR24482165 Whole embryo Whole embryo 4 hpf not recorded SRP436676 515.18
SRR24482167 Whole embryo Whole embryo 3 hpf not recorded SRP436676 514.98
SRR24482173 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 514.13
SRR24482171 Whole embryo Whole embryo 1 hpf not recorded SRP436676 511.64
SRR24482172 Whole embryo Whole embryo 30 mpf not recorded SRP436676 503.28
SRR24482174 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 489.03
SRR24482175 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 478.91
SRR24482133 Whole embryo Whole embryo 6 hpf not recorded SRP436676 468.36
SRR24482134 Whole embryo Whole embryo 5 hpf not recorded SRP436676 420.22
SRR24482137 Whole embryo Whole embryo 3 hpf not recorded SRP436676 371.37
SRR24482142 Whole embryo Whole embryo 30 mpf not recorded SRP436676 371.22
SRR24482140 Whole embryo Whole embryo 2 hpf not recorded SRP436676 368.02
SRR24482141 Whole embryo Whole embryo 1 hpf not recorded SRP436676 357.69
SRR24482135 Whole embryo Whole embryo 4 hpf not recorded SRP436676 355.74
SRR24482139 Whole embryo Whole embryo 2 hpf not recorded SRP436676 350.07
SRR24482144 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 347.49
SRR24482138 Whole embryo Whole embryo 3 hpf not recorded SRP436676 336.11
SRR24482145 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 334.22
SRR24482143 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 325.44
SRR24482136 Whole embryo Whole embryo 4 hpf not recorded SRP436676 319.97
SRR24482146 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 767.61
SRR24482147 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 714.35
SRR24482150 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 469.54
SRR24482149 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 455.13
SRR24482148 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 889.23
SRR24482154 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 805.08
SRR24482151 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 586.84
SRR24482152 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 557.47

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydractinia symbiolongicarpus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated14HSymV2.0_g06.10834_t10.984748089398022
Negatively correlated52HSymV2.0_g04.06375_t1-0.956677412094279

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydractinia symbiolongicarpus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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