Gene detail

Detailed information of HSymV2.0_g06.10546_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_6:16565480...16567351
NR annotation: XP_002161456.1, NEDD8-activating enzyme E1 regulatory subunit [Hydra vulgaris]
Species abbreviation HSYMB · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6NTW6	NEDD8-activating enzyme E1 regulatory subunit OS=Xenopus laevis OX=8355 GN=nae1 PE=2 SV=1
Q8VBW6	NEDD8-activating enzyme E1 regulatory subunit OS=Mus musculus OX=10090 GN=Nae1 PE=1 SV=1
Q9Z1A5	NEDD8-activating enzyme E1 regulatory subunit OS=Rattus norvegicus OX=10116 GN=Nae1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005560 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00899 all species →	ThiF	ThiF family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR030667 all species →	Family	NEDD8-activating enzyme E1 regulatory subunit APP-BP1	Interproscan
IPR045886 all species →	Family	ThiF/MoeB/HesA family	Interproscan
IPR035985 all species →	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR000594 all species →	Domain	THIF-type NAD/FAD binding fold	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953 all species →	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019781 all species →	Molecular Function	NEDD8 activating enzyme activity	Interproscan
GO:0045116 all species →	Biological Process	protein neddylation	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0032446 all species →	Biological Process	protein modification by small protein conjugation	Interproscan
GO:0008641 all species →	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04532	NAE1, APPBP1; NEDD8-activating enzyme E1 regulatory subunit	-	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.