Detailed information of HSymV2.0_g08.12910_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_8:3189487...3230073
NR annotation: XP_047125679.1, protein furry homolog-like [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O94915Protein furry homolog-like OS=Homo sapiens OX=9606 GN=FRYL PE=1 SV=2
Q5TBA9Protein furry homolog OS=Homo sapiens OX=9606 GN=FRY PE=1 SV=1
E9Q8I9Protein furry homolog OS=Mus musculus OX=10090 GN=Fry PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002627 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF14225
all species →
MOR2-PAG1_CCell morphogenesis C-terminalFamilyInterproscan
PF14222
all species →
MOR2-PAG1_NCell morphogenesis N-terminalFamilyInterproscan
PF14228
all species →
MOR2-PAG1_midCell morphogenesis central regionFamilyInterproscan
PF19421
all species →
Fry_CFurry protein C-terminalDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR025481
all species →
DomainCell morphogenesis protein C-terminalInterproscan
IPR025614
all species →
DomainCell morphogenesis protein N-terminalInterproscan
IPR016024
all species →
Homologous_superfamilyArmadillo-type foldInterproscan
IPR039867
all species →
FamilyProtein furry/Tao3/Mor2Interproscan
IPR029473
all species →
DomainCell morphogenesis central regionInterproscan
IPR045842
all species →
DomainProtein furry, C-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR12295
all species →
FURRY-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000902
all species →
Biological Processcell morphogenesisInterproscan
GO:0005938
all species →
Cellular Componentcell cortexInterproscan
GO:0030427
all species →
Cellular Componentsite of polarized growthInterproscan
GO:0031175
all species →
Biological Processneuron projection developmentInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for HSymV2.0_g08.12910_t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g08.12910_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples
44TPM > 0
3Conditions
118.2Max TPM
68.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole embryo 36 36 65.78 118.22
Whole embryo · Triptolide 20 uM 4 4 87.74 116.49
Whole embryo · DMSO 0.5% 4 4 77.92 111.44

Per sample · hover a bar for the full sample record

Show the sample table (44 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR24482153 Whole embryo Whole embryo 7 hpf not recorded SRP436676 118.22
SRR24482133 Whole embryo Whole embryo 6 hpf not recorded SRP436676 110.38
SRR24482134 Whole embryo Whole embryo 5 hpf not recorded SRP436676 104.15
SRR24482138 Whole embryo Whole embryo 3 hpf not recorded SRP436676 101.23
SRR24482145 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 100.15
SRR24482140 Whole embryo Whole embryo 2 hpf not recorded SRP436676 99.84
SRR24482141 Whole embryo Whole embryo 1 hpf not recorded SRP436676 98.85
SRR24482143 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 96.49
SRR24482142 Whole embryo Whole embryo 30 mpf not recorded SRP436676 95.93
SRR24482144 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 93.11
SRR24482136 Whole embryo Whole embryo 4 hpf not recorded SRP436676 91.54
SRR24482139 Whole embryo Whole embryo 2 hpf not recorded SRP436676 90.24
SRR24482135 Whole embryo Whole embryo 4 hpf not recorded SRP436676 88.73
SRR24482177 Whole embryo Whole embryo 1 hpf not recorded SRP436676 85.29
SRR24482137 Whole embryo Whole embryo 3 hpf not recorded SRP436676 82.91
SRR24482167 Whole embryo Whole embryo 3 hpf not recorded SRP436676 57.48
SRR24482173 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 57.36
SRR24482174 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 56.97
SRR24482172 Whole embryo Whole embryo 30 mpf not recorded SRP436676 56.53
SRR24482165 Whole embryo Whole embryo 4 hpf not recorded SRP436676 56.48
SRR24482171 Whole embryo Whole embryo 1 hpf not recorded SRP436676 56.44
SRR24482170 Whole embryo Whole embryo 2 hpf not recorded SRP436676 55.10
SRR24482169 Whole embryo Whole embryo 2 hpf not recorded SRP436676 54.09
SRR24482168 Whole embryo Whole embryo 3 hpf not recorded SRP436676 53.44
SRR24482161 Whole embryo Whole embryo 7 hpf not recorded SRP436676 53.34
SRR24482175 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 51.07
SRR24482166 Whole embryo Whole embryo 4 hpf not recorded SRP436676 48.05
SRR24482163 Whole embryo Whole embryo 6 hpf not recorded SRP436676 46.96
SRR24482162 Whole embryo Whole embryo 7 hpf not recorded SRP436676 45.52
SRR24482176 Whole embryo Whole embryo 1 hpf not recorded SRP436676 43.93
SRR24482160 Whole embryo Whole embryo 24 hpf not recorded SRP436676 29.46
SRR24482157 Whole embryo Whole embryo 48 hpf not recorded SRP436676 26.24
SRR24482159 Whole embryo Whole embryo 24 hpf not recorded SRP436676 22.07
SRR24482156 Whole embryo Whole embryo 72 hpf not recorded SRP436676 20.77
SRR24482158 Whole embryo Whole embryo 48 hpf not recorded SRP436676 13.36
SRR24482155 Whole embryo Whole embryo 72 hpf not recorded SRP436676 6.42
SRR24482150 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 116.49
SRR24482149 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 113.66
SRR24482146 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 60.97
SRR24482147 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 59.84
SRR24482151 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 111.44
SRR24482152 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 109.07
SRR24482154 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 48.56
SRR24482148 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 42.60

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydractinia symbiolongicarpus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated36HSymV2.0_g09.16409_t10.982517638120327
Negatively correlated4HSymV2.0_g08.13799_t1-0.906337635522724

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydractinia symbiolongicarpus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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