Gene detail

Detailed information of HSymV2.0_g08.13169_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_8:6311700...6335839
NR annotation: AAV97963.1, protein-tyrosine kinase, partial [Hydractinia echinata]
Species Hydractinia symbiolongicarpus · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

HSymV2.0_g08.13169_t1

ATGGTCACAATGCCAGAGGTTTCCACTCAAAAGAGAAACTCAGCAGGGATTAGTCCCACGAAACTGGAACGTCATCAATCTGCCCTTAAAACAACACTGCATGTGTTTCTTCCTAATGGGGAGTTTAGGGCTGTCAAGTTTGGGGATAATTCAGACTTAAAGAGTATAATTGACATCGTCACTCGAAGACTAGGTGCTAATATTTCACTTTCTTCAAAGTTTTATGGTATAAAATTTGAGCATGTGGAAACAAAAGCATTTTTTTGGTTAAATCCGGCTTTGACGATGACTGATGTTAAAAATAAATTTGAAAATGAACACAAAGATGAAAAATGGAGATATAACTTGCGGATTCGTTATTTACCAATTGTTTTCAAAGACCTGTATACCATTGATAAAACAACATTTTATTTTTTGTATGACCAGATTCGCACAGATTATATGAAAAATATAGCAGAAACTGTTGAAACAAGTTTGGCTTTTCAATTGGGAGTGCTGGAAATGAAGCGCTTTTTTAACAACATGCCACAATCTGCCTTGGATAAAAAATCAAATTTGGATTTTATTGAGAAGGAAATTGGTTTAGAAAGGTTTCTGCCAAATACAGTACTGGATCATATGAAAAACAAAGACATACGCAAGAAAATACAGACGCTTTTCAAGCAATATGCAGATTACAAAGAAGATTTTTGTTGCTTCGAATTTTATAAGTTATTATTGAGTGTACATAGATTTGACTTAGAAGCATATAAATGCTCCCTAGGGAGTGTATGGTCAATTGCAGTAGATGTTGTTATTGGTCCTAATGATGGAATTAGCTACAGACCTGAACAGGGGTCGAAAATCACAAACATGGCACATTTTAAAGATATCCGTTCTATATATACATCTAAAGTTGGTGCCATGCCTGGAAAAGCAAACTTAAATATACAAGTGGAAGGAAATAATGAGCCACTCGTTTTTCTGGTTGATCCGATTTCAAAAGCTACAGAACTTGCAGATTTGATTGATGGTTACTGTAGTATTGTTAGTTTTCATCAACCAAAGTCATTAATAATAAAACGTGCTGATAGTTATCGAACGTTGCCGTCAGTGCCTAAAGTTGCAGACAGTGATAGTTCGAACACAAGCTCTGTTAGCATCATCAACCCACGCCTGTCGCAAGGTTCTTTGTTGTACAATAACAGTAAAAACGGAGATTTTAATGATTATGCAGAAATTGCGGATGATGATGATGAAAGTGATTATGCACACCCAATGTCAGCAAAAGACTATGAAGTGGCTAGAGATGATTTGACATTAGATGAAATCATAGGTCAAGGTCAATTTGGTGATGTTTATCAAGGCACTTTCAAATCAAAAATTAGTTCTGCTGAGATCCCTGTTGCAGTCAAAACGTATAAAATTGAACTTGACAAAGAGCAAGAAGATGGTACAAGAGCAGAAAAGTTTCTTGAAGAAGCTTATCTGATGCAACAATTTGATCATCCACATGTTATTAAGCTAATTGGAATTGTATCAGACAGCCCAAGTTATATTATTATGGAGCTGGCTTCCTATGGGGAGCTACGTTCATACCTACAACAGTACAGAACTCAAACAGAATCTGAAAGGTTGCTGACATACATATATCAACTTTGTACAGCGTTGTCTTATTTAGAAAGTAGAAATTTTGTTCATAGAGACATAGCAGCTAGAAATATACTTGTAGCAGACCCCCATACAATTAAACTTGCGGATTTTGGACTTTCTCGATGGATTGATGAAGAGCAGTCATATTATAAAGCGTCTAAGGGCAAATTACCTATAAAATGGATGGCTCCAGAATCGATAAACTTTCGTCGTTTCTCATCTGCATCAGATGTATGGATGTTTGGTGTTTGTTGTTGGGAAATACTCATGTACGGTGTTAAGCCTTTCCAAGGTGTTCCTAATGAGAAAGTAATTGGAAAAATAGAGAACGGTGAAAGGTTACCACTGCCTCCAAATTGTGCACCGACTCTGTATCATCTGATGACAGAATGTTGGCATTATGAACCATCAAAGAGACCCACTTTTCAAGAGCTGAAATCAAGATTATCGCAAATAAAATACGAAGAAAGTTTTTCAGGCCAGgaaagaaagaaaaaagaagacagaagaaTTAAAATGAATTCATTTGGGAGTGACGAAGCATTTGCTCCACCGAAGCCTGCGAGACCAACTGGTAGGATTGAACCATTGTTTTTAAATAAATCGCAAACGCTTCCAAGGAATTTGCGTCAATCACCAGAAACCGCGCTTACAAGTATGAGCACTTCGACTTTACCACGACCAGTTACAAAAAATGAAAGTCCTTTTATTGTTCAGAGATTATCATGGTCTGGTGCAAGGCATCATGCCAGACAGGAGAAGCAGAAACGCGAAGCAGACGACAAAGCGAAGTTGATTCGCAAAACAAGAGCGGAGCAAGAAAGTCTTCGTCGCAAATTAAATGAGCAAAAAGAACAGTCTGATGCAGACAGCCAGTGGTTGATGAGCGAAGAAGTCGCCAGCTACGCCGAGGTGCAGCCTTCTGCTGATGATCAAAACTTTCAGAGGCATAGTTGGAAAGATGGGTTACACCCAAGCGGATCCAAATCCGATTCGGAACAACTTGGTTATGATTTATTTAAAGAAGATTTTGCTCGGGATATAATCGAAAAGAAAGCGAAAAGAAACTCGACCTTACGAAGAAGCATACCACTATGGGGATTCGAGAGAAATGATTTCACTAACGAAAAGAAACCTTCTCCCCTTGCAAGAGAAGATCCACCTCCTACGACCCCTCCAGGGAATGAGTCGGCAATAGAACCATCATCACCTTCTGTAATAAGTACTGATAATGTACGTGATGAGGACATACAACCAGTAGCCGATGTTGTTGACAGTGCTAAACCAAAACTCTCCCGAAGCAATTCTGCTTCAGATACCTATGCTAAACCAATTAAAAAAAAAGATCGTCTCGAGGAAACAATTCCCCGTTGCAACACAACTGGACAAATTGAAAATAAGAACAGCTCGCCACGTTTGAGAACTAGGTCGGAACAAAAACCGACTAAGAAGGAAAAGCAAGAAAACAAATCTACAGTGGATGTGGTGTACCAACATACGACAAGCGTGGTAAAGTCAGTTATTGAGTTAAATACAGGTGTCCAGCATGCGCAGCCTGAAGAATTTGTTGACTTAGTCAAAGTTGTCGGCTTAAATCTTCGCGACCTTCTTGCCGAAGTTGATAAAGAGATTCAACTCGTACCTTCAATATCACAAAAAGAGATCGAAATGGCGCATAAAGTTTTATCCTCAGACATGGCTGAACTGGTGAACACAATGAAACTAGCGCAAAAATATGCAGACACAACATTAGATCAGCAATATAGACGTAATATGTTAGCCGCTGCCCACGCGCTCGCCATAGATGCTAAGAACCTTTACGATACTTTTTCGAAACTTAAAAATAAAGTTCTTgaagagacggaagaagaagaagaagaggaacaaaagaaagaagTGGAAAGTTTAGTGGAAGAAGCGTTACCTAACTAA

Transcript

HSymV2.0_g08.13169_t1

TTTTAGATGAAAATGTTAGTATATTATTGGGATATTTTATGATGATGTGATGTATTCAAATGGTCACAATGCCAGAGGTTTCCACTCAAAAGAGAAACTCAGCAGGGATTAGTCCCACGAAACTGGAACGTCATCAATCTGCCCTTAAAACAACACTGCATGTGTTTCTTCCTAATGGGGAGTTTAGGGCTGTCAAGTTTGGGGATAATTCAGACTTAAAGAGTATAATTGACATCGTCACTCGAAGACTAGGTGCTAATATTTCACTTTCTTCAAAGTTTTATGGTATAAAATTTGAGCATGTGGAAACAAAAGCATTTTTTTGGTTAAATCCGGCTTTGACGATGACTGATGTTAAAAATAAATTTGAAAATGAACACAAAGATGAAAAATGGAGATATAACTTGCGGATTCGTTATTTACCAATTGTTTTCAAAGACCTGTATACCATTGATAAAACAACATTTTATTTTTTGTATGACCAGATTCGCACAGATTATATGAAAAATATAGCAGAAACTGTTGAAACAAGTTTGGCTTTTCAATTGGGAGTGCTGGAAATGAAGCGCTTTTTTAACAACATGCCACAATCTGCCTTGGATAAAAAATCAAATTTGGATTTTATTGAGAAGGAAATTGGTTTAGAAAGGTTTCTGCCAAATACAGTACTGGATCATATGAAAAACAAAGACATACGCAAGAAAATACAGACGCTTTTCAAGCAATATGCAGATTACAAAGAAGATTTTTGTTGCTTCGAATTTTATAAGTTATTATTGAGTGTACATAGATTTGACTTAGAAGCATATAAATGCTCCCTAGGGAGTGTATGGTCAATTGCAGTAGATGTTGTTATTGGTCCTAATGATGGAATTAGCTACAGACCTGAACAGGGGTCGAAAATCACAAACATGGCACATTTTAAAGATATCCGTTCTATATATACATCTAAAGTTGGTGCCATGCCTGGAAAAGCAAACTTAAATATACAAGTGGAAGGAAATAATGAGCCACTCGTTTTTCTGGTTGATCCGATTTCAAAAGCTACAGAACTTGCAGATTTGATTGATGGTTACTGTAGTATTGTTAGTTTTCATCAACCAAAGTCATTAATAATAAAACGTGCTGATAGTTATCGAACGTTGCCGTCAGTGCCTAAAGTTGCAGACAGTGATAGTTCGAACACAAGCTCTGTTAGCATCATCAACCCACGCCTGTCGCAAGGTTCTTTGTTGTACAATAACAGTAAAAACGGAGATTTTAATGATTATGCAGAAATTGCGGATGATGATGATGAAAGTGATTATGCACACCCAATGTCAGCAAAAGACTATGAAGTGGCTAGAGATGATTTGACATTAGATGAAATCATAGGTCAAGGTCAATTTGGTGATGTTTATCAAGGCACTTTCAAATCAAAAATTAGTTCTGCTGAGATCCCTGTTGCAGTCAAAACGTATAAAATTGAACTTGACAAAGAGCAAGAAGATGGTACAAGAGCAGAAAAGTTTCTTGAAGAAGCTTATCTGATGCAACAATTTGATCATCCACATGTTATTAAGCTAATTGGAATTGTATCAGACAGCCCAAGTTATATTATTATGGAGCTGGCTTCCTATGGGGAGCTACGTTCATACCTACAACAGTACAGAACTCAAACAGAATCTGAAAGGTTGCTGACATACATATATCAACTTTGTACAGCGTTGTCTTATTTAGAAAGTAGAAATTTTGTTCATAGAGACATAGCAGCTAGAAATATACTTGTAGCAGACCCCCATACAATTAAACTTGCGGATTTTGGACTTTCTCGATGGATTGATGAAGAGCAGTCATATTATAAAGCGTCTAAGGGCAAATTACCTATAAAATGGATGGCTCCAGAATCGATAAACTTTCGTCGTTTCTCATCTGCATCAGATGTATGGATGTTTGGTGTTTGTTGTTGGGAAATACTCATGTACGGTGTTAAGCCTTTCCAAGGTGTTCCTAATGAGAAAGTAATTGGAAAAATAGAGAACGGTGAAAGGTTACCACTGCCTCCAAATTGTGCACCGACTCTGTATCATCTGATGACAGAATGTTGGCATTATGAACCATCAAAGAGACCCACTTTTCAAGAGCTGAAATCAAGATTATCGCAAATAAAATACGAAGAAAGTTTTTCAGGCCAGgaaagaaagaaaaaagaagacagaagaaTTAAAATGAATTCATTTGGGAGTGACGAAGCATTTGCTCCACCGAAGCCTGCGAGACCAACTGGTAGGATTGAACCATTGTTTTTAAATAAATCGCAAACGCTTCCAAGGAATTTGCGTCAATCACCAGAAACCGCGCTTACAAGTATGAGCACTTCGACTTTACCACGACCAGTTACAAAAAATGAAAGTCCTTTTATTGTTCAGAGATTATCATGGTCTGGTGCAAGGCATCATGCCAGACAGGAGAAGCAGAAACGCGAAGCAGACGACAAAGCGAAGTTGATTCGCAAAACAAGAGCGGAGCAAGAAAGTCTTCGTCGCAAATTAAATGAGCAAAAAGAACAGTCTGATGCAGACAGCCAGTGGTTGATGAGCGAAGAAGTCGCCAGCTACGCCGAGGTGCAGCCTTCTGCTGATGATCAAAACTTTCAGAGGCATAGTTGGAAAGATGGGTTACACCCAAGCGGATCCAAATCCGATTCGGAACAACTTGGTTATGATTTATTTAAAGAAGATTTTGCTCGGGATATAATCGAAAAGAAAGCGAAAAGAAACTCGACCTTACGAAGAAGCATACCACTATGGGGATTCGAGAGAAATGATTTCACTAACGAAAAGAAACCTTCTCCCCTTGCAAGAGAAGATCCACCTCCTACGACCCCTCCAGGGAATGAGTCGGCAATAGAACCATCATCACCTTCTGTAATAAGTACTGATAATGTACGTGATGAGGACATACAACCAGTAGCCGATGTTGTTGACAGTGCTAAACCAAAACTCTCCCGAAGCAATTCTGCTTCAGATACCTATGCTAAACCAATTAAAAAAAAAGATCGTCTCGAGGAAACAATTCCCCGTTGCAACACAACTGGACAAATTGAAAATAAGAACAGCTCGCCACGTTTGAGAACTAGGTCGGAACAAAAACCGACTAAGAAGGAAAAGCAAGAAAACAAATCTACAGTGGATGTGGTGTACCAACATACGACAAGCGTGGTAAAGTCAGTTATTGAGTTAAATACAGGTGTCCAGCATGCGCAGCCTGAAGAATTTGTTGACTTAGTCAAAGTTGTCGGCTTAAATCTTCGCGACCTTCTTGCCGAAGTTGATAAAGAGATTCAACTCGTACCTTCAATATCACAAAAAGAGATCGAAATGGCGCATAAAGTTTTATCCTCAGACATGGCTGAACTGGTGAACACAATGAAACTAGCGCAAAAATATGCAGACACAACATTAGATCAGCAATATAGACGTAATATGTTAGCCGCTGCCCACGCGCTCGCCATAGATGCTAAGAACCTTTACGATACTTTTTCGAAACTTAAAAATAAAGTTCTTgaagagacggaagaagaagaagaagaggaacaaaagaaagaagTGGAAAGTTTAGTGGAAGAAGCGTTACCTAACTAAACTTGACTGTAGCTAGTGTCCAGCTTGAAGCTCACTATATAATGCAGTCGAAAGAGAAGTGATTCCTCGAATGCTTTAATTTTAGACAAGTAGAGAAAGTATTGAGGGTCTATTTAAAAGTAAACTTGAACTATAAGTTTAACAAAATCATGCGTGAGAAGAAATACGTCTTTAACATAATTAAGCAGTATTTGTCTATGCTTTTGTTTACATTCTTACAATTACAATACCTCATAAAATTGTATCGATTTGTACCGTGTGAGTATCGATTTGTTTCGTATGG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q00944	Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2
Q91738	Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2
Q05397	Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003173 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03623 all species →	Focal_AT	Focal adhesion targeting region	Domain	Interproscan
PF18038 all species →	FERM_N_2	FERM N-terminal domain	Domain	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan
PF21477 all species →	FERM_C_FAK1	FAK1/PYK2, FERM domain C-lobe	Domain	Interproscan
PF00373 all species →	FERM_M	FERM central domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR020635 all species →	Domain	Tyrosine-protein kinase, catalytic domain	Interproscan
IPR036137 all species →	Homologous_superfamily	Focal adhesion kinase, targeting (FAT) domain superfamily	Interproscan
IPR041784 all species →	Domain	FAK1/PYK2, FERM domain C-lobe	Interproscan
IPR005189 all species →	Domain	Focal adhesion kinase, targeting (FAT) domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR041390 all species →	Domain	Focal adhesion kinase, N-terminal	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR000299 all species →	Domain	FERM domain	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR049385 all species →	Domain	FAK1-like, FERM domain C-lobe	Interproscan
IPR019749 all species →	Domain	Band 4.1 domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR014352 all species →	Homologous_superfamily	FERM/acyl-CoA-binding protein superfamily	Interproscan
IPR019748 all species →	Domain	FERM central domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR035963 all species →	Homologous_superfamily	FERM superfamily, second domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46221 all species →	FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan
GO:0005925 all species →	Cellular Component	focal adhesion	Interproscan
GO:0007172 all species →	Biological Process	signal complex assembly	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05725	PTK2, FAK; focal adhesion kinase 1	EC:2.7.10.2	Protein phosphatases and associated proteins	ko01009	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g08.13169_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples

44TPM > 0

3Conditions

159.6Max TPM

100.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole embryo	36	36	92.31	150.33
Whole embryo · Triptolide 20 uM	4	4	140.85	159.60
Whole embryo · DMSO 0.5%	4	4	137.62	145.53

Per sample · hover a bar for the full sample record

Show the sample table (44 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR24482161	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	150.33
SRR24482162	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	146.55
SRR24482153	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	143.11
SRR24482165	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	122.93
SRR24482133	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	120.86
SRR24482163	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	120.34
SRR24482167	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	115.53
SRR24482166	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	110.49
SRR24482144	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	108.40
SRR24482177	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	106.64
SRR24482139	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	105.53
SRR24482143	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	104.89
SRR24482169	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	104.22
SRR24482137	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	104.06
SRR24482135	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	102.24
SRR24482168	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	100.30
SRR24482138	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	96.25
SRR24482140	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	95.17
SRR24482170	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	93.36
SRR24482134	Whole embryo	Whole embryo	5 hpf	not recorded	SRP436676	91.91
SRR24482141	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	91.59
SRR24482142	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	91.26
SRR24482136	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	90.04
SRR24482145	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	89.45
SRR24482171	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	77.90
SRR24482173	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	75.71
SRR24482174	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	75.35
SRR24482160	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	74.59
SRR24482172	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	69.71
SRR24482176	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	66.23
SRR24482175	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	64.19
SRR24482159	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	63.03
SRR24482157	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	54.39
SRR24482158	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	39.34
SRR24482156	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	32.92
SRR24482155	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	24.48
SRR24482147	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	159.60
SRR24482150	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	135.33
SRR24482149	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	134.35
SRR24482146	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	134.10
SRR24482148	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	145.53
SRR24482154	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	141.36
SRR24482151	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	133.89
SRR24482152	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	129.68

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydractinia symbiolongicarpus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	44	HSymV2.0_g10.18099_t1	0.98210641815282
Negatively correlated	14	HSymV2.0_g09.15197_t1	-0.898030509294452

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydractinia symbiolongicarpus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →