Gene detail

Detailed information of HSymV2.0_g09.17455_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_9:27722575...27727551
NR annotation: XP_002159593.1, ERO1-like protein beta isoform X1 [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9V3A6	Ero1-like protein OS=Drosophila melanogaster OX=7227 GN=Ero1L PE=2 SV=2
Q86YB8	ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2
Q6DD71	ERO1-like protein alpha OS=Xenopus laevis OX=8355 GN=ero1a PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003960 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04137 all species →	ERO1	Endoplasmic Reticulum Oxidoreductin 1 (ERO1)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR007266 all species →	Family	Endoplasmic reticulum oxidoreductin 1	Interproscan
IPR037192 all species →	Homologous_superfamily	ERO1-like superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12613 all species →	ERO1-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0015035 all species →	Molecular Function	protein-disulfide reductase activity	Interproscan
GO:0016972 all species →	Molecular Function	thiol oxidase activity	Interproscan
GO:0034975 all species →	Biological Process	protein folding in endoplasmic reticulum	Interproscan
GO:0071949 all species →	Molecular Function	FAD binding	Interproscan
GO:0005789 all species →	Cellular Component	endoplasmic reticulum membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10950	ERO1L; ERO1-like protein alpha	EC:1.8.4.-	Lipid and atherosclerosis	ko05417	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g09.17455_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples

44TPM > 0

3Conditions

43.0Max TPM

19.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole embryo	36	36	18.49	42.99
Whole embryo · Triptolide 20 uM	4	4	20.84	25.05
Whole embryo · DMSO 0.5%	4	4	26.54	38.14

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR24482153	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	42.99
SRR24482133	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	29.62
SRR24482143	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	28.20
SRR24482144	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	27.96
SRR24482142	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	27.19
SRR24482137	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	26.60
SRR24482141	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	26.12
SRR24482134	Whole embryo	Whole embryo	5 hpf	not recorded	SRP436676	26.06
SRR24482145	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	25.50
SRR24482135	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	25.46
SRR24482138	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	24.49
SRR24482165	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	24.45
SRR24482139	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	23.81
SRR24482136	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	23.01
SRR24482177	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	20.92
SRR24482140	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	20.90
SRR24482162	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	20.13
SRR24482167	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	19.91
SRR24482168	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	18.88
SRR24482166	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	18.56
SRR24482169	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	17.97
SRR24482173	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	17.19
SRR24482161	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	16.47
SRR24482176	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	16.43
SRR24482170	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	16.42
SRR24482163	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	15.24
SRR24482172	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	14.49
SRR24482171	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	14.00
SRR24482175	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	11.43
SRR24482174	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	11.14
SRR24482160	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	3.13
SRR24482156	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	2.87
SRR24482157	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	2.62
SRR24482159	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	2.16
SRR24482158	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	1.66
SRR24482155	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	1.60
SRR24482149	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	25.05
SRR24482150	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	23.90
SRR24482147	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	20.17
SRR24482146	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	14.25
SRR24482152	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	38.14
SRR24482151	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	34.90
SRR24482154	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	16.71
SRR24482148	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	16.38

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.