Detailed information of HSymV2.0_g10.18735_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_10:21011824...21014876
NR annotation: XP_028410526.1, 60S ribosomal protein L27a-like [Dendronephthya gigantea]
Species Hydractinia symbiolongicarpus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P48160Large ribosomal subunit protein uL15 OS=Dictyostelium discoideum OX=44689 GN=rpl27a PE=3 SV=1
P57728Large ribosomal subunit protein uL15B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl2801 PE=1 SV=1
P36585Large ribosomal subunit protein uL15A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl2802 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006014 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00828
all species →		Ribosomal_L27ARibosomal proteins 50S-L15, 50S-L18e, 60S-L27AFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001196
all species →		Conserved_siteLarge ribosomal subunit protein uL15, conserved siteInterproscan
IPR030878
all species →		FamilyLarge ribosomal subunit protein uL15Interproscan
IPR021131
all species →		DomainLarge ribosomal subunit protein uL15/eL18Interproscan
IPR036227
all species →		Homologous_superfamilyLarge ribosomal subunit protein uL15/eL18 superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11721
all species →		60S RIBOSOMAL PROTEIN L27AInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003735
all species →		Molecular Functionstructural constituent of ribosomeInterproscan
GO:0005840
all species →		Cellular ComponentribosomeInterproscan
GO:0006412
all species →		Biological ProcesstranslationInterproscan
GO:0015934
all species →		Cellular Componentlarge ribosomal subunitInterproscan
GO:0022625
all species →		Cellular Componentcytosolic large ribosomal subunitInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K02900RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae-Ribosomeko03011deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g10.18735_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples
44TPM > 0
3Conditions
5,910.3Max TPM
1,046.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole embryo 36 36 1,115.31 5,910.27
Whole embryo · Triptolide 20 uM 4 4 722.77 879.13
Whole embryo · DMSO 0.5% 4 4 746.79 967.78

Per sample · hover a bar for the full sample record

Show the sample table (44 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR24482156 Whole embryo Whole embryo 72 hpf not recorded SRP436676 5,910.27
SRR24482155 Whole embryo Whole embryo 72 hpf not recorded SRP436676 5,574.29
SRR24482158 Whole embryo Whole embryo 48 hpf not recorded SRP436676 3,912.16
SRR24482157 Whole embryo Whole embryo 48 hpf not recorded SRP436676 3,540.47
SRR24482159 Whole embryo Whole embryo 24 hpf not recorded SRP436676 2,975.63
SRR24482160 Whole embryo Whole embryo 24 hpf not recorded SRP436676 2,296.30
SRR24482161 Whole embryo Whole embryo 7 hpf not recorded SRP436676 858.90
SRR24482163 Whole embryo Whole embryo 6 hpf not recorded SRP436676 740.35
SRR24482162 Whole embryo Whole embryo 7 hpf not recorded SRP436676 720.41
SRR24482175 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 676.27
SRR24482168 Whole embryo Whole embryo 3 hpf not recorded SRP436676 668.58
SRR24482170 Whole embryo Whole embryo 2 hpf not recorded SRP436676 655.90
SRR24482176 Whole embryo Whole embryo 1 hpf not recorded SRP436676 630.98
SRR24482166 Whole embryo Whole embryo 4 hpf not recorded SRP436676 629.35
SRR24482167 Whole embryo Whole embryo 3 hpf not recorded SRP436676 624.40
SRR24482169 Whole embryo Whole embryo 2 hpf not recorded SRP436676 619.36
SRR24482165 Whole embryo Whole embryo 4 hpf not recorded SRP436676 618.40
SRR24482171 Whole embryo Whole embryo 1 hpf not recorded SRP436676 605.81
SRR24482173 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 604.92
SRR24482172 Whole embryo Whole embryo 30 mpf not recorded SRP436676 590.72
SRR24482174 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 553.18
SRR24482142 Whole embryo Whole embryo 30 mpf not recorded SRP436676 495.09
SRR24482153 Whole embryo Whole embryo 7 hpf not recorded SRP436676 470.71
SRR24482137 Whole embryo Whole embryo 3 hpf not recorded SRP436676 459.88
SRR24482133 Whole embryo Whole embryo 6 hpf not recorded SRP436676 419.37
SRR24482144 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 404.13
SRR24482135 Whole embryo Whole embryo 4 hpf not recorded SRP436676 401.54
SRR24482139 Whole embryo Whole embryo 2 hpf not recorded SRP436676 399.02
SRR24482140 Whole embryo Whole embryo 2 hpf not recorded SRP436676 396.36
SRR24482177 Whole embryo Whole embryo 1 hpf not recorded SRP436676 394.82
SRR24482145 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 394.05
SRR24482138 Whole embryo Whole embryo 3 hpf not recorded SRP436676 385.73
SRR24482141 Whole embryo Whole embryo 1 hpf not recorded SRP436676 384.21
SRR24482134 Whole embryo Whole embryo 5 hpf not recorded SRP436676 383.65
SRR24482136 Whole embryo Whole embryo 4 hpf not recorded SRP436676 381.76
SRR24482143 Whole embryo Whole embryo Unfertilized egg not recorded SRP436676 374.29
SRR24482146 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 879.13
SRR24482147 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 865.94
SRR24482150 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 616.99
SRR24482149 Whole embryo · Triptolide 20 uM Whole embryo 7 hpf Triptolide 20 uM SRP436676 529.04
SRR24482148 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 967.78
SRR24482154 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 866.62
SRR24482151 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 599.83
SRR24482152 Whole embryo · DMSO 0.5% Whole embryo 7 hpf DMSO 0.5% SRP436676 552.94

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Hydractinia symbiolongicarpus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated46HSymV2.0_g11.20325_t10.998358478809146
Negatively correlated5HSymV2.0_g05.09506_t1-0.943313364633948

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Hydractinia symbiolongicarpus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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