Gene detail

Detailed information of HSymV2.0_g10.19082_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_10:25223708...25225803
NR annotation: XP_047134504.1, tRNA (guanine(37)-N1)-methyltransferase isoform X2 [Hydra vulgaris]
Species Hydractinia symbiolongicarpus · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
F6VSS6	tRNA (guanine(37)-N(1))-methyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt5 PE=3 SV=1
Q9D0C4	tRNA (guanine(37)-N(1))-methyltransferase OS=Mus musculus OX=10090 GN=Trmt5 PE=1 SV=1
Q3MHN8	tRNA (guanine(37)-N(1))-methyltransferase OS=Bos taurus OX=9913 GN=TRMT5 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006308 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02475 all species →	Met_10	Met-10+ like-protein	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR025792 all species →	Family	tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic	Interproscan
IPR030382 all species →	Domain	SAM-dependent methyltransferase TRM5/TYW2-type	Interproscan
IPR029063 all species →	Homologous_superfamily	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23245 all species →	TRNA METHYLTRANSFERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0030488 all species →	Biological Process	tRNA methylation	Interproscan
GO:0052906 all species →	Molecular Function	tRNA (guanine(37)-N1)-methyltransferase activity	Interproscan
GO:0002939 all species →	Biological Process	tRNA N1-guanine methylation	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0008175 all species →	Molecular Function	tRNA methyltransferase activity	Interproscan
GO:0009019 all species →	Molecular Function	obsolete tRNA (guanine-N1-)-methyltransferase activity	Interproscan
GO:0070901 all species →	Biological Process	mitochondrial tRNA methylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K15429	TRM5, TRMT5; tRNA (guanine37-N1)-methyltransferase	EC:2.1.1.228	Transfer RNA biogenesis	ko03016	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of HSymV2.0_g10.19082_t1 across 44 RNA-seq samples of Hydractinia symbiolongicarpus. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

44Samples

44TPM > 0

3Conditions

80.8Max TPM

51.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole embryo	36	36	49.46	75.60
Whole embryo · Triptolide 20 uM	4	4	71.82	80.76
Whole embryo · DMSO 0.5%	4	4	46.69	52.57

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR24482165	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	75.60
SRR24482167	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	75.21
SRR24482173	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	68.28
SRR24482169	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	67.74
SRR24482142	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	65.18
SRR24482139	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	64.56
SRR24482141	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	63.80
SRR24482176	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	62.99
SRR24482172	Whole embryo	Whole embryo	30 mpf	not recorded	SRP436676	61.78
SRR24482174	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	61.36
SRR24482135	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	61.13
SRR24482138	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	60.69
SRR24482168	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	60.66
SRR24482143	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	60.28
SRR24482144	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	60.13
SRR24482166	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	60.00
SRR24482170	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	59.99
SRR24482137	Whole embryo	Whole embryo	3 hpf	not recorded	SRP436676	58.97
SRR24482136	Whole embryo	Whole embryo	4 hpf	not recorded	SRP436676	58.84
SRR24482171	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	56.86
SRR24482134	Whole embryo	Whole embryo	5 hpf	not recorded	SRP436676	55.29
SRR24482177	Whole embryo	Whole embryo	1 hpf	not recorded	SRP436676	53.51
SRR24482140	Whole embryo	Whole embryo	2 hpf	not recorded	SRP436676	51.97
SRR24482145	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	51.60
SRR24482133	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	51.51
SRR24482175	Whole embryo	Whole embryo	Unfertilized egg	not recorded	SRP436676	48.93
SRR24482163	Whole embryo	Whole embryo	6 hpf	not recorded	SRP436676	43.86
SRR24482161	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	40.04
SRR24482153	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	36.97
SRR24482162	Whole embryo	Whole embryo	7 hpf	not recorded	SRP436676	26.78
SRR24482155	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	11.48
SRR24482159	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	9.06
SRR24482156	Whole embryo	Whole embryo	72 hpf	not recorded	SRP436676	9.05
SRR24482160	Whole embryo	Whole embryo	24 hpf	not recorded	SRP436676	8.97
SRR24482157	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	8.90
SRR24482158	Whole embryo	Whole embryo	48 hpf	not recorded	SRP436676	8.67
SRR24482150	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	80.76
SRR24482149	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	71.52
SRR24482147	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	70.80
SRR24482146	Whole embryo · Triptolide 20 uM	Whole embryo	7 hpf	Triptolide 20 uM	SRP436676	64.20
SRR24482151	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	52.57
SRR24482154	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	48.37
SRR24482152	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	48.27
SRR24482148	Whole embryo · DMSO 0.5%	Whole embryo	7 hpf	DMSO 0.5%	SRP436676	37.56

Source: CnidoSite RNA-seq expression matrices (HSYMB_TPM, StringTie quantification over 44 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.