Gene detail

Detailed information of KXJ07970.1 in Exaiptasia diaphana

Genomic Location: LJWW01000603.1:51869...57421
NR annotation: XP_020911830.1, glutamate--cysteine ligase regulatory subunit [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48507	Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1
O09172	Glutamate--cysteine ligase regulatory subunit OS=Mus musculus OX=10090 GN=Gclm PE=1 SV=1
P48508	Glutamate--cysteine ligase regulatory subunit OS=Rattus norvegicus OX=10116 GN=Gclm PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005404 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00248 all species →	Aldo_ket_red	Aldo/keto reductase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036812 all species →	Homologous_superfamily	NADP-dependent oxidoreductase domain superfamily	Interproscan
IPR023210 all species →	Domain	NADP-dependent oxidoreductase domain	Interproscan
IPR032963 all species →	Family	Glutamate--cysteine ligase regulatory subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13295 all species →	GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006750 all species →	Biological Process	glutathione biosynthetic process	Interproscan
GO:0017109 all species →	Cellular Component	glutamate-cysteine ligase complex	Interproscan
GO:0030234 all species →	Molecular Function	enzyme regulator activity	Interproscan
GO:0035226 all species →	Molecular Function	glutamate-cysteine ligase catalytic subunit binding	Interproscan
GO:0035229 all species →	Biological Process	positive regulation of glutamate-cysteine ligase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11205	GCLM; glutamate--cysteine ligase regulatory subunit	-	Ferroptosis	ko04216	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ07970.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples

71TPM > 0

2Conditions

141.1Max TPM

99.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole animal · aposymbiotic	36	35	98.56	141.06
whole animal · symbiotic	36	36	99.90	140.27

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6202345	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	141.06
SRR6202344	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	137.15
SRR6202357	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	127.33
SRR6202241	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	118.30
SRR6202234	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	111.96
SRR6202343	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	109.30
SRR6202254	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	108.53
SRR6202242	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	107.61
SRR6202260	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	106.97
SRR6202258	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	105.36
SRR6202235	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	105.24
SRR6202233	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	103.58
SRR6202237	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	103.02
SRR6202261	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	102.90
SRR6202205	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	101.24
SRR6202346	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	99.26
SRR6202259	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	98.88
SRR6202212	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	98.29
SRR6202240	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	98.28
SRR6202238	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	98.09
SRR6202239	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	97.64
SRR6202256	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	97.05
SRR6202211	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	96.38
SRR6202257	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	96.17
SRR6202255	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	95.56
SRR6202204	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	93.56
SRR6202236	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	93.42
SRR6202206	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	92.96
SRR6202203	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	92.67
SRR6202207	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	92.41
SRR6202208	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	92.38
SRR6202210	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	90.06
SRR6202209	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	88.70
SRR6202363	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	83.44
SRR6202358	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	63.58
SRR6202364	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	0.00
SRR6202342	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	140.27
SRR6202349	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	124.70
SRR6202304	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	116.58
SRR6202338	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	116.14
SRR6202303	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	115.34
SRR6202263	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	114.60
SRR6202284	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	114.49
SRR6202305	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	114.32
SRR6202339	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	113.39
SRR6202340	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	112.48
SRR6202283	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	111.65
SRR6202306	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	109.67
SRR6202309	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	109.44
SRR6202285	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	109.41
SRR6202277	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	109.29
SRR6202282	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	106.22
SRR6202341	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	105.66
SRR6202276	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	105.28
SRR6202262	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	105.10
SRR6202310	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	104.32
SRR6202337	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	103.00
SRR6202308	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	100.37
SRR6202348	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	95.62
SRR6202307	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	94.88
SRR6202347	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	91.22
SRR6202352	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	88.20
SRR6202278	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	86.28
SRR6202355	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	82.30
SRR6202356	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	82.29
SRR6202279	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	81.22
SRR6202351	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	79.03
SRR6202280	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	78.23
SRR6202350	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	76.78
SRR6202281	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	74.99
SRR6202354	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	71.41
SRR6202353	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	52.25

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.