Gene detail

Detailed information of KXJ09294.1 in Exaiptasia diaphana

Genomic Location: LJWW01000489.1:95805...107303
NR annotation: XP_020909422.1, lysine-specific demethylase 5A [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

KXJ09294.1

ATGACCATGACGGACGATGTCGAAGAATTCACCTTTATTTCTCCACCAGAGGCTCCAGTTTTTGAGCCATCTCAAGAGGAATTCCAGGACCCTTTGGCTTATATCGCCAAGATTCGACCGTATGCCGAGAAAACTGGTATTTGCAAGATACGACCACCCCCGGATTGGAGACCTCCATTTGCTGTAGACGTTGACAATTTTACCTTTACGCCACGAATACAACGTCTGAATGAACTTGAGGCCAGAACAAGAGTTAAACTTAATTTCCTTGATGGTCTGGCTAAATTTTGGGAACTCCAGGGAACTGTGTTTAAAGTTCCACAAGTTGAGAGGAAAAGTTTAGATTTATTCAGACTTTACAAGACTGTGCATGAAGAAGGTGGATTCGAGTATATCACAAGGAAGAAGAAATGGACAAATGTGGCTAGAAAGATGGGCTATGCTCTTGGCAAATCTGCCCCCTCGTTGCTACGAATGAACTATGAGAARTACTTGTACCCCTATGATATCTTTATGGTTGGAGCATTTACTGCAGAAGCAGTGCCTACTGTGGACCAGATGAAGAGAGAAGAGAAATATGAAATACCTTTACCTTCACCAAATACCAACTACCAAGCATCCAGAAGATCAAGGAGAGGAAGACCAGAGGMTGCTTCAGCATCTGACATTGACTATGATAGTAATCCAGAGTTAAAGAAGCTGCAATTTATTGCACCTGGACCCAAAATGTCTGGATTGACATCCAAGAAAGAAGATACAAATAATACCAGYACAACAGAGGTTAAGAAAGAACCATTGGAAGAGAGTCCTAAAGTTTATGCAGGTGATAGTTCTCCTGCTAAGTCAACACGATTTAGTAAACACAAAGACAGTGGCAAGTTAAAGATGGAAAACATTAAGATTGGTAAAGAACCAGAATTAACTAGACGAAGACCTGTCAGACAAGCCAGTAAAGTGTATGGTTCCAGTAAATCATGGTTATTAGAAGAGTATGTCTGTCAAGTCTGTACTAAGGGGGATTCTGAGGGTTCAATGTTGCTGTGTGATGGTTGTGATGACAGTTATCATACTTATTGCTTGATACCCCCACTAGTATCTGTACCTAAGGGTGACTGGAGATGCCCTAGATGTGTGGCAGAGGAATGCAACAAGCCCCAAGAGGCTTTTGGCTTTGAGCAGGCCAAGCAAATTTACACTCTACAATCATTTGGTCAAAGAGCTGATAAGTTTAAAAAAGAGTACTTCAAAATGCCACCAAGGGAGGTTCCAACACAGATTGTAGAAAAGGAATTCTGGAGACTAGTATCTTCCATGGATGAAGATCTTCAAGTTGAGTATGGTGCTGATCTTCACACTGCCAAACATGGTAGTGGCTTTCCCAGGAAAGGTACAACTACTACTAATGAAGAAGAGTATTATGCCATGTCTCCATGGAATCTCAACAACATGGCCAACCTTGAAAGATCTGTATTATGTCATATCAGTGCTGATATCTCTGGAATGAAGGTTCCATGGATATATGTGGGCATGTGTTTTAGCAGTTTTTGCTGGCATAATGAAGACCACTGGAGCTACTCTATCAACTATATGCACTGGGGCGAGCCAAAGACATGGTATGGTATACCTGGTGATGCCGCTGAAGAGTTTGAAATGGCGATTAAAGAAGCAGCTCCAGAACTGTTTGAAGAACAGCCTGACTTACTGCATCAGTTGGTGACACTCATTAACCCCAATGACCTTACAGCTAAAGGGGTTCCTGTGGTCAGGACAAATCAGTGTGCAGGAGAGTTTGTTGTTACATTCCCCAGGGCATATCATGCAGGATTTAACAATGGCTATAACCTTGCAGAAGCTGTTAACTTTGCWACWGCTGATTGGCTTCCTATTGGGCGCAAGTGCATTGATCATTATCGTGAGATGAGTCGTAACCCAGTATTCTCTCATGAAGAGCTTGTGTGTAAAATGGCTGCTGATCCTGATGGTTTAGATCTTGATCTGGCTAAGGCTGTTTACGATGAGCTGTCTTGTATAGTGGATTGTGAAACTAAACGGCGTATGCRGCTGTTATCTGAAGGATGCCAAGAATTAGATAAACCAGAGGCATTTGAACTTCTTCCTGAYGATGAGAGACAGTGTGCTGTCTGTAAAACAACTTGTTTCATGTCAGCTGTCACATGTACATGTGAACCAGAGAGACTAACCTGCATTGACTGTGCTAAAGACMTGTGTTCATGTGCAACACAAAACAAAACCTTAAGGTATCGTTACACAGTTAAAGAGCTACCATCTATGCTGCTAAAGCTAAAACAAAGAGCTGATTCATTTGATAACTGGGCAAGTGATGTCAAAAGGGCCTTGGAGCCATGTGACAGTAAAGTTGGTGTCTCAGACCTCAAAGATCTTGTGGTTACAGCAGAACAAAGTCAGTTCCCAGAATGCGATCTCCTTCAGCTTCTAAAGTCAACTCTAGCCGAGGCAGAGAGATGTGCAAGTGTTGCTCTACAACTTGTGAGCAGAAAACACAGAACCCGACACAATCTTCCTACTTCGCTGGTGCAGGCTCCTAAACTCGGCTTGGATGAGTTACAGGCATTTGGCCAACAACTTGAAAGTCTACCTTGTGTTATCAGAGAAGCGGATTTGGTCCAGGATTTAATGACACATGTTGAAAGCTTCCAGTGTGAGGCGCAAAAGGTCTTACAAGAACCAGTGATTGACACAGAAAGACTCCAGCAACTACTAGACACTGGTACAAGCTTAGATGTAGAACTACCAGAAATACCAAAACTGAAACAGGAACTTTGCCAAGCAAAATGGCTGGAGCAGGTGAATGTCACACTAGAGAATACACAAGCTGTGTCTTTTGACACATTACAAGAACTACTTGCAACAGGAGAAACATTGGCACAGAAACCTRCTGTATCGAAGGCTGTTGGTGAACTGCGGGAGCTGGTTCAACTTGGTGAAAAATGGGAAGAAAAGGCCAAGCTTTGTCTGCAAGCAAGACCCCGTCATGTTATGGCTACCGTAGAAGCCATCGTTCARGAGGCGTCCCACGTGCCGGTATTTCTKCCTAATGTTAGCGCTCTCAATGAATCGCTAAGAAAAGCTACTGAATGGTCAGACAAAGTCGACAAAGTTCAGAATGATAAGTATTATCCATATCTGGAAGTTCTTGAAGCACTGGTCATGCGTGGTCGGCCCATTCCTGTTCGACTAGAGCAGCTTCCCCAGATGGAGTCACAAGTTGCTGCTGCTAGAGCCTGGAGAGATAGGGCAGCAAGAACCTTCCTYAAGAAGAACTCCAACACTCCATTACTTGAAATATTGTTGCCAAGAAAAGACATAGGAAACTATAAATCCTGCCCAAGACCACGTAAAAAGAAAGAGAAAGAGAAAGAGAAGGAAAAAGAGAAAGAGATAGTGATGGATTTGACAGCAATTGACGATTATATCGGCAGGGATCCATTACACCAAATAGCTCAGTTTAAAGAAGGAGAACTCAAAGAGATGGAAGCTGTTAGTAAACTTCGCAAACAGCACATCTCTCGTTACAAAGAAGAGGAATCAAAACGTCAGTCAGGAGAGTCTGTCGACGGCCAGTATTGTATATGTCGTCGTGGTCCCGAAGGCTTCATGTTAATGTGTGAGTTGTGTAAAGAATGGTATCACGGTTCATGCGTACCTCTACCGCGTACACAAAGCGGCAAGACTGTGGGCAAGGGATCTGCTGGCTTAGAAGCAGCTAAGGAACTTAAATACTTGTGTCCACTATGTCTCAGGTCAAGGCGACCTCGTCTAGAAACTATATTATCACTTCTTGTATCGTTACAAAAGCTGCCTGTTAGACTTCCAGAGGGGGAAGCGCTTCAGTTTTTAACAGAGAGAGCAATGAACTGGCAAGACCGTGCGAGACAACTGCTGGCTGATACAGACATAAACAGTATTATGAACTCAGACAAAGGGACATCAGGAGTGTCAGCTGAAAACCTGTCAGCATCAGCAGCACTACTAAGACTTGCTAATATTACTACTGTTGATAGTAGTAGTSCATTGGTCTTACCAGATGATAAGAAAGCTGCACTAGAAGAACTTATGATGGAAGGTGATCTACTCGAGGTAACACTTGACGAGACCGATCAATTATGGAAGTGTCTAAGAAGTCAACGTTCATTTGAAGACACAAAGGTATTTGGTATCAAGCAAGAAAAGGAAAAAGTGAAAAGAAAACGCCGCAAGAAAGACGAGGATGATAAAACCAAGCCAGCAAGACGATCATCAACATCGTCCAACACATCAAACAACGACGGACCCAAGAAGCGTCGAAAATCCAAGCAAGTGATTAATGTGGACGAAGACGACGAAGACGAAGTTTGTGCTTCCAAGGCTTGCGGCCGTCCATCAGGAGACGAGGTGGACTGGGTACAATGCGATTCATGTGAACAATGGTTTCATTTGGTGTGTATAGGACTGACAAGCGAGAAGGCTGAGGCTCTGGAATCCTTCAAATGTAGTCTGTGCGTCGAACATGTAGTTAACATATCAAGCACCAATGATTCTCCTGAATCTATCAATGTTGATGTGGATAGTACGACGCCATACGCTAATTCACCGACCGACGTCATGGAAGTCGACCAATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q3UXZ9	Lysine-specific demethylase 5A OS=Mus musculus OX=10090 GN=Kdm5a PE=1 SV=2
P29375	Lysine-specific demethylase 5A OS=Homo sapiens OX=9606 GN=KDM5A PE=1 SV=3
P41229	Lysine-specific demethylase 5C OS=Homo sapiens OX=9606 GN=KDM5C PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004250 (this species only)
Transcription factor family	ARID · all TF in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21323 all species →	KDM5_C-hel	Lysine-specific demethylase 5, C-terminal helical domain	Domain	Interproscan
PF01388 all species →	ARID	ARID/BRIGHT DNA binding domain	Domain	Interproscan
PF02928 all species →	zf-C5HC2	C5HC2 zinc finger	Domain	Interproscan
PF00628 all species →	PHD	PHD-finger	Domain	Interproscan
PF08429 all species →	PLU-1	PLU-1-like protein	Family	Interproscan
PF02373 all species →	JmjC	JmjC domain, hydroxylase	Domain	Interproscan
PF02375 all species →	JmjN	jmjN domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR048615 all species →	Domain	Lysine-specific demethylase 5, C-terminal helical domain	Interproscan
IPR001965 all species →	Domain	Zinc finger, PHD-type	Interproscan
IPR001606 all species →	Domain	ARID DNA-binding domain	Interproscan
IPR036431 all species →	Homologous_superfamily	ARID DNA-binding domain superfamily	Interproscan
IPR019786 all species →	Conserved_site	Zinc finger, PHD-type, conserved site	Interproscan
IPR011011 all species →	Homologous_superfamily	Zinc finger, FYVE/PHD-type	Interproscan
IPR003347 all species →	Domain	JmjC domain	Interproscan
IPR004198 all species →	Domain	Zinc finger, C5HC2-type	Interproscan
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR019787 all species →	Domain	Zinc finger, PHD-finger	Interproscan
IPR003349 all species →	Domain	JmjN domain	Interproscan
IPR013637 all species →	Domain	Lysine-specific demethylase-like domain	Interproscan
IPR047970 all species →	Domain	Lysine-specific demethylase 5A, second PHD finger	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10694 all species →	LYSINE-SPECIFIC DEMETHYLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0000785 all species →	Cellular Component	chromatin	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006338 all species →	Biological Process	chromatin remodeling	Interproscan
GO:0006355 all species →	Biological Process	regulation of DNA-templated transcription	Interproscan
GO:0010468 all species →	Biological Process	regulation of gene expression	Interproscan
GO:0032452 all species →	Molecular Function	histone demethylase activity	Interproscan
GO:0034647 all species →	Molecular Function	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11446	KDM5, JARID1; [histone H3]-trimethyl-L-lysine4 demethylase	EC:1.14.11.67	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ09294.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples

71TPM > 0

2Conditions

107.0Max TPM

68.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole animal · aposymbiotic	36	35	59.74	88.98
whole animal · symbiotic	36	36	76.47	106.96

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6202345	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	88.98
SRR6202233	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	82.24
SRR6202260	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	80.83
SRR6202258	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	80.73
SRR6202241	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	79.72
SRR6202242	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	78.76
SRR6202234	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	78.00
SRR6202261	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	77.05
SRR6202344	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	76.84
SRR6202343	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	75.99
SRR6202346	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	75.29
SRR6202259	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	72.15
SRR6202358	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	70.73
SRR6202212	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	70.64
SRR6202209	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	70.46
SRR6202210	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	69.04
SRR6202206	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	64.57
SRR6202211	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	63.71
SRR6202363	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.73
SRR6202208	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.48
SRR6202207	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	61.16
SRR6202205	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	59.61
SRR6202254	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	52.16
SRR6202236	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	52.09
SRR6202237	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	48.86
SRR6202235	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.04
SRR6202255	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	46.79
SRR6202238	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	45.80
SRR6202257	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.30
SRR6202256	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.45
SRR6202203	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.89
SRR6202240	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.57
SRR6202204	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.54
SRR6202239	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.32
SRR6202357	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	31.03
SRR6202364	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	0.00
SRR6202349	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	106.96
SRR6202305	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	104.48
SRR6202354	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	102.94
SRR6202306	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	102.04
SRR6202303	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	100.47
SRR6202284	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	98.55
SRR6202285	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	96.84
SRR6202304	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	95.08
SRR6202307	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	93.86
SRR6202308	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	92.96
SRR6202282	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	91.64
SRR6202309	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	89.53
SRR6202283	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	84.13
SRR6202310	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	82.79
SRR6202348	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	78.60
SRR6202341	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	77.28
SRR6202263	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	73.91
SRR6202340	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	73.85
SRR6202339	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	73.35
SRR6202262	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	72.14
SRR6202342	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	70.95
SRR6202353	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	69.02
SRR6202276	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	66.58
SRR6202337	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	65.15
SRR6202338	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	61.45
SRR6202350	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	60.50
SRR6202277	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	59.98
SRR6202352	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	59.29
SRR6202280	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	59.13
SRR6202281	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	58.19
SRR6202278	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	57.37
SRR6202355	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	57.03
SRR6202347	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	56.31
SRR6202279	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	55.30
SRR6202351	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.62
SRR6202356	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.56

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.