Genomic Location: LJWW01000364.1:66066...72302
NR annotation: KXJ11489.1, CSC1-like protein 2 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families
| CDS |
| KXJ11489.1 |
| Protein |
| KXJ11489.1 |
| UniProt accession | Description |
|---|---|
| A0A8V0ZB02 | Mechanosensitive cation channel TMEM63B OS=Gallus gallus OX=9031 GN=TMEM63B PE=3 SV=1 |
| Q5T3F8 | Mechanosensitive cation channel TMEM63B OS=Homo sapiens OX=9606 GN=TMEM63B PE=1 SV=1 |
| Q3TWI9 | Mechanosensitive cation channel TMEM63B OS=Mus musculus OX=10090 GN=Tmem63b PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006805 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02714 all species → | RSN1_7TM | Calcium-dependent channel, 7TM region, putative phosphate | Family | Interproscan |
| PF14703 all species → | PHM7_cyt | Cytosolic domain of 10TM putative phosphate transporter | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR012677 all species → | Homologous_superfamily | Nucleotide-binding alpha-beta plait domain superfamily | Interproscan |
| IPR045122 all species → | Family | Calcium permeable stress-gated cation channel 1-like | Interproscan |
| IPR035979 all species → | Homologous_superfamily | RNA-binding domain superfamily | Interproscan |
| IPR003864 all species → | Domain | CSC1/OSCA1-like, 7TM region | Interproscan |
| IPR027815 all species → | Domain | CSC1/OSCA1-like, cytosolic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13018 all species → | PROBABLE MEMBRANE PROTEIN DUF221-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005227 all species → | Molecular Function | calcium-activated cation channel activity | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
KXJ11489.1.Transcript abundance of KXJ11489.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole animal · aposymbiotic | 36 | 34 | 59.93 | 87.47 | |
| whole animal · symbiotic | 36 | 35 | 74.80 | 159.73 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR6202358 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 87.47 |
| SRR6202211 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 78.86 |
| SRR6202260 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 78.38 |
| SRR6202363 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 77.16 |
| SRR6202343 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 76.35 |
| SRR6202234 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 72.24 |
| SRR6202344 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 71.79 |
| SRR6202357 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 71.36 |
| SRR6202206 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 70.55 |
| SRR6202346 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 70.25 |
| SRR6202261 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 70.03 |
| SRR6202242 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 69.36 |
| SRR6202233 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 67.42 |
| SRR6202241 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 67.15 |
| SRR6202259 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 66.70 |
| SRR6202210 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 66.32 |
| SRR6202209 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 65.62 |
| SRR6202205 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 64.28 |
| SRR6202212 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 63.38 |
| SRR6202254 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 61.38 |
| SRR6202207 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 61.30 |
| SRR6202258 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 59.74 |
| SRR6202236 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 59.73 |
| SRR6202208 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 59.04 |
| SRR6202237 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 58.41 |
| SRR6202238 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 56.66 |
| SRR6202235 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 55.79 |
| SRR6202255 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 55.15 |
| SRR6202203 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 50.70 |
| SRR6202256 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 49.50 |
| SRR6202204 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 46.14 |
| SRR6202239 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 44.79 |
| SRR6202240 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 42.78 |
| SRR6202257 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 41.60 |
| SRR6202345 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 0.00 |
| SRR6202364 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 0.00 |
| SRR6202342 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 159.73 |
| SRR6202303 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 103.14 |
| SRR6202305 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 102.74 |
| SRR6202284 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 101.89 |
| SRR6202354 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 99.83 |
| SRR6202285 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 96.86 |
| SRR6202306 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 93.91 |
| SRR6202304 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 92.43 |
| SRR6202341 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 88.11 |
| SRR6202340 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 88.00 |
| SRR6202263 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 86.95 |
| SRR6202262 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 85.67 |
| SRR6202339 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 84.21 |
| SRR6202337 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 77.38 |
| SRR6202338 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 73.57 |
| SRR6202277 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 71.96 |
| SRR6202280 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 70.30 |
| SRR6202352 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 70.06 |
| SRR6202276 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 69.84 |
| SRR6202351 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 69.73 |
| SRR6202310 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 69.57 |
| SRR6202281 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 69.03 |
| SRR6202348 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 67.90 |
| SRR6202282 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 66.01 |
| SRR6202283 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 65.58 |
| SRR6202347 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 65.24 |
| SRR6202308 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 64.03 |
| SRR6202309 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 63.96 |
| SRR6202356 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 61.25 |
| SRR6202355 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 61.14 |
| SRR6202278 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 60.33 |
| SRR6202307 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 59.33 |
| SRR6202279 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 59.31 |
| SRR6202350 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 53.51 |
| SRR6202349 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 20.33 |
| SRR6202353 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM,
StringTie quantification over 72 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Exaiptasia diaphana tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 33 | KXJ26710.1 | 0.894778517669258 |
| Negatively correlated | 7 | KXJ20985.1 | -0.766875356477701 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Exaiptasia diaphana, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 2 available assays. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: ChIP-seq · ATAC-seq.
| Sample | Methylation profile |
|---|---|
| whole_animal_aposymbiotic_1 | open |
| whole_animal_aposymbiotic_2 | open |
| whole_animal_aposymbiotic_3 | open |
| whole_animal_aposymbiotic_4 | open |
| whole_animal_aposymbiotic_5 | open |
| whole_animal_aposymbiotic_6 | open |
| whole_animal_aposymbiotic_7 | open |
| whole_animal_aposymbiotic_8 | open |
| whole_animal_aposymbiotic_9 | open |
| whole_animal_symbiotic_1 | open |
| whole_animal_symbiotic_10 | open |
| whole_animal_symbiotic_11 | open |
| whole_animal_symbiotic_12 | open |
| whole_animal_symbiotic_13 | open |
| whole_animal_symbiotic_14 | open |
| whole_animal_symbiotic_2 | open |
| whole_animal_symbiotic_3 | open |
| whole_animal_symbiotic_4 | open |
| whole_animal_symbiotic_5 | open |
| whole_animal_symbiotic_6 | open |
| whole_animal_symbiotic_7 | open |
| whole_animal_symbiotic_8 | open |
| whole_animal_symbiotic_9 | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |