Genomic Location: LJWW01000023.1:71570...105336
NR annotation: KXJ27107.1, DNA-dependent protein kinase catalytic subunit [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families
| CDS |
| KXJ27107.1 |
| Protein |
| KXJ27107.1 |
| UniProt accession | Description |
|---|---|
| Q8QGX4 | DNA-dependent protein kinase catalytic subunit OS=Gallus gallus OX=9031 GN=PRKDC PE=2 SV=1 |
| Q9DEI1 | DNA-dependent protein kinase catalytic subunit OS=Xenopus laevis OX=8355 GN=prkdc PE=2 SV=1 |
| Q8WN22 | DNA-dependent protein kinase catalytic subunit OS=Canis lupus familiaris OX=9615 GN=PRKDC PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001506 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF20502 all species → | DNAPKcs_CC1-2 | DNA-dependent protein kinase catalytic subunit, CC1/2 | Repeat | Interproscan |
| PF00454 all species → | PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | Family | Interproscan |
| PF20500 all species → | DNA-PKcs_N | DNA-PKcs, N-terminal | Repeat | Interproscan |
| PF02259 all species → | FAT | FAT domain | Repeat | Interproscan |
| PF02260 all species → | FATC | FATC domain | Family | Interproscan |
| PF08163 all species → | DNAPKcs_CC3 | DNA-dependent protein kinase catalytic subunit, CC3 | Repeat | Interproscan |
| PF19704 all species → | DNAPKcs_CC5 | DNA-PKcs, CC5 | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046803 all species → | Domain | DNA-dependent protein kinase catalytic subunit, CC1/2 | Interproscan |
| IPR011990 all species → | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR000403 all species → | Domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Interproscan |
| IPR037706 all species → | Domain | DNA-dependent protein kinase catalytic subunit, catalytic domain | Interproscan |
| IPR018936 all species → | Conserved_site | Phosphatidylinositol 3/4-kinase, conserved site | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR014009 all species → | Domain | PIK-related kinase | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR050517 all species → | Family | DNA Damage Response and Repair Kinase | Interproscan |
| IPR012582 all species → | Domain | DNA-dependent protein kinase catalytic subunit, CC3 | Interproscan |
| IPR046804 all species → | Domain | DNA-PKcs, N-terminal | Interproscan |
| IPR003152 all species → | Domain | FATC domain | Interproscan |
| IPR003151 all species → | Domain | PIK-related kinase, FAT | Interproscan |
| IPR045581 all species → | Domain | DNA-dependent protein kinase catalytic subunit, CC5 | Interproscan |
| IPR036940 all species → | Homologous_superfamily | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11139 all species → | ATAXIA TELANGIECTASIA MUTATED ATM -RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0004677 all species → | Molecular Function | DNA-dependent protein kinase activity | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0016301 all species → | Molecular Function | kinase activity | Interproscan |
| GO:0000723 all species → | Biological Process | telomere maintenance | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006302 all species → | Biological Process | double-strand break repair | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0006303 all species → | Biological Process | double-strand break repair via nonhomologous end joining | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06642 | PRKDC; DNA-dependent protein kinase catalytic subunit | EC:2.7.11.1 | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of KXJ27107.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole animal · aposymbiotic | 36 | 35 | 6.28 | 17.56 | |
| whole animal · symbiotic | 36 | 30 | 5.78 | 13.02 |
Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM,
StringTie quantification over 72 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.