Gene detail

Detailed information of KXJ27450.1 in Exaiptasia diaphana

Genomic Location: LJWW01000020.1:44292...52146
NR annotation: XP_020897096.1, tumor necrosis factor alpha-induced protein 3 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

KXJ27450.1

ATGCTATCTCATCCTCATTTTGAGCGAAGCATCTCTCTGAACGATTTGGACACATCTGTAAAAGTACGGGAGCATGTCCAAAAAGATGTTGTTAACCCAGAAGATGACTCAAAACAYTCCTTCTTCAAATCCATGAGCCAGTTTACATTGGTTCTTCGAAGCTTCAAAGACTTYCCCGTTGACTACAAGAAGTTCTTGTACAGTTATCTAGTCGATTTGGTGGTATTTCGTGAACTTGAAGMATGCAARAGGCTGAACTGGTGTGAAGGCTTGTTTCCWATGGTTCCTGTTTTAACAATGGGTGAYGGRAATTGTTTGATGCATGCTGCTTCTATTGGGATGTGGGCTGTYAGTGACCGCTATCATACCTTGAGGAAGTTGGTGTACAATGCTCTGCTTGAAGATGTTGACAGATTTTATCACAAAAGATGGCAAAGAGAGATGGAAGTCAGCAATCTATCTCGTCATGGTTACGAAATGACAGAAGAACAATGGACCAAAGAATGGCAAATTGTGCTGGAACTTGTCTCACAGGGTGAATATCCMCTTGGCAACAATGGTATGCAGTACAGCAGTCTTGAGGAAATCCACATMTTTGTTCTTGCCAATGTTCTTCGCCGTACAATCATTGTAATATCAAATGACATACAGAGAGGGAACTATGATGAGCCCTTGACCCCCCTGAATTATCCAGGTATATACCTCCCCCTGAATTGGGACCCTGTTGACTGTGTGAAAACCCCTCTKGTRATTGGCTATTCACAAGGACATTTTACAGCTGTGGTAAGTTTTGAGGATGGAGTATTTGACAGAGGTGAAGTTATTGATGACTATGGTGTGAAGGTTCATGGCGTACCCCTTCAACAACACAAYGGCAAACCTCTYCCTRTCCATTTTCTGCTTGAAGATGAAGAAGATATTGGTGATGGTCTRATACGGCAGTATTTAGACTGTACAAGAGTCCCCCATAGGGACCCCCAGAGTAACAAGGATGTTATYACTTTAGCTGCAAAGCTACAATTCATGAAACCCCCAGGATGCATTGCTGGTTTGGTTGATTCTTTCTTTTCATCTGCTCAAGATACTTACACAATTATGTTGCATCAGAAATCTGAAAATCATAGTTGTCAAACTCCTTTACTCCAATTGGAGCCGTGCAAGACAGAAAACTGTCAGTTTTTTGGTACATATGAGACTCTGTACTTATGCTCGAAGTGCCTTGATGAATATTTGATGAATGAATCTTCTGGTGCAGCAGGGAAGGTAAAAGAGGCACTGGTCAACAAACAAATGGAAGGAAGGCATTATGAAAGCCATCAAAAACAGCAGCAACAACCCAATGAATTACAACTACAGCAAGGCTTTGAAAAACATCAACATCAACAACAACAACAACTGCTGTCTGAGCAACAGCAAAATCCCCAAAAGCTACAGCAGAAWATGTGTGCTAAAGGTGACTGCAATCACATCTCATACCAAGGATGTGGTGATCTATGTTTGAGATGCTATGACTCAGATGTTTTGTTAAGACAACAGAACGCTACGTCGTCAAATAATGCAACTCCAACAACATCCTGCGTCAACAAGGTCAATGGGTGTGAGTTCTTTGGCATTCCACAACAGGAGGGTTTCTGTTCAAGATGCTACGAAAGATTTTGCGCAGAAATGCAGTCACTTCGAATTGAAGACAGCCGCAAACCAAGAGGACAAACTGGCCAGGGACTGCCACAGGAACGACGATGTCAAAACCAGGGTTGTACAAGACCAGCCTGTCCAGAGCTGTATGACAGATGTGTTGAATGCTATGGTGACTGCATCAAACAGTTTATTCATGCAAATGAAAGACAATCCATGGAAGCCTTTGCTGCTCCGTCACCTGAGCAGCCTCCTCAAACCCCCTTGCTTCCAAAGCTGTGCACCATGCCTGCATGTCAGAATGAAGGACAAGAGAAGTATGGCGGCCATTGTGTCCACTGCTTTCAAATCAGACCGTACGAAGTGCCTCTGGATATCGAACGACCATCTCAAACATTCAAACAGAATGAACAAGGATTTTCGTCACCTTTTTCCCATCAGCCTCCGTCACACAACGTCCATTCACTATTGTACTGTGAAACACCAGCATGCGGACAGCCACTCGGCGAAACAAGTGGCACTCTCTGTACAAAATGTATAATGAAAAAGTTCCAATTGAAGAGAAAAGTTTCCCCACAACAACAGCAGCCATTTTTTATCGAAAAAACATTACCAAGCAATGAAGAACCTCAGAGTAGTGAGAGAAAAGAGGAAGTCTTACGTGCTCGTGAGAGGCTACAGCCATTGTTTATCCCGCCACCTCGTGACCAACTCCCGTTTGGTAACACTGCACCAAGAATTCCAGAGAGAAAAGTGCTGGAGGTGTTTAAACCTGGAAATGGTAACGCAGAAAACCAAGAGTCTGGAACACGTTGCCTCACACCAAACTGTCCTTTCTTTGCCAACCCTGAGACTCAATTCCTGTGCACCAGCTGCCACCAGAAAGAGAAGAAAGAATGGGAAAAGATTAATAAAATGGCACAAAGACAACTACCGCAACTTCGTAATTGTGCGTTTACAAACTGCTATAACTGGGAAAGCCCAGGAAATGGTGGTCTGTGTGACAAGTGCTTTCAGACGGGTATCCGTAATGAGAAGGTCTGGGATTCACAAAACCGACGACAACCGCCGAGAGAACCCCAGCGACAACAACCAGTTTCGCCAAAGAAAAGCTCTCCTCGTAAGACTACAAATTTCATCAGCACCGGTTTGCCTTGTAATTCCCCAGGCTGTCTCAGGTTTGGTACAGAAGACAAACAAGGCTATTGCGATCGCTGCTTCGAAAAACAACAATCCAGGCAAGCCATTAAACCGAGTCCACTCACAGAACTACCATCCTCTGCCAATATTAGACGTGAAAGACCTGAGCAAATCCCAAACCCCAATCCTATTGCGCATGAGCCCGTTCTAGTCTCCCAGCCGCAATCTAGAGTTTTTGGAGAGAGGTCTGGACGATTTTCTAATATTTGCGTACAAGAAGGATGTAAAATGACTGGAAGTGCACATTTTGGTGGATATTGCTCCAAGTGCTTTGAAGACTACACAAAGTTACACAGTTATCCAGAATCAGTTGCAGATTTGGTATCATGTCAAGAGCCCCCATCGCCAGAACAAAGTGTCARCACCGAACCGGTTTCAACAGGTTTGACTACTTTGCCGCCAATCTCTCCACGAACCTGCGCAATGCCACGATGTAATAACCAAGTGCAGCCAAGCACTATGAGTCACTGTAGAGACTGTTTAGCCAAACTATACCCCCAGTACGCACGCGCAAATAATATGACATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q4R8W3	Tumor necrosis factor alpha-induced protein 3 OS=Macaca fascicularis OX=9541 GN=TNFAIP3 PE=2 SV=1
P21580	Tumor necrosis factor alpha-induced protein 3 OS=Homo sapiens OX=9606 GN=TNFAIP3 PE=1 SV=1
Q60769	Tumor necrosis factor alpha-induced protein 3 OS=Mus musculus OX=10090 GN=Tnfaip3 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004548 (this species only)
Ubiquitin family	DUB\|OTU\|OTU · all ubiquitin genes in this species
Ubiquitin family	UBD\|ZnF\|ZnF_A20 · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02338 all species →	OTU	OTU-like cysteine protease	Family	Interproscan
PF01754 all species →	zf-A20	A20-like zinc finger	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002653 all species →	Domain	Zinc finger, A20-type	Interproscan
IPR003323 all species →	Domain	OTU domain	Interproscan
IPR051346 all species →	Family	OTU Domain-Containing Deubiquitinase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13367 all species →	UBIQUITIN THIOESTERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0004843 all species →	Molecular Function	cysteine-type deubiquitinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0007010 all species →	Biological Process	cytoskeleton organization	Interproscan
GO:0016477 all species →	Biological Process	cell migration	Interproscan
GO:0030177 all species →	Biological Process	positive regulation of Wnt signaling pathway	Interproscan
GO:0035523 all species →	Biological Process	protein K29-linked deubiquitination	Interproscan
GO:0070530 all species →	Molecular Function	K63-linked polyubiquitin modification-dependent protein binding	Interproscan
GO:0071947 all species →	Biological Process	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	Interproscan
GO:1990168 all species →	Biological Process	protein K33-linked deubiquitination	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11859	TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3	EC:3.4.19.12	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ27450.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples

71TPM > 0

2Conditions

131.4Max TPM

66.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole animal · aposymbiotic	36	36	58.06	82.81
whole animal · symbiotic	36	35	74.49	131.38

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6202241	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	82.81
SRR6202261	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	80.91
SRR6202242	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	80.61
SRR6202233	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	79.58
SRR6202344	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	78.92
SRR6202234	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	77.28
SRR6202260	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	75.02
SRR6202258	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	72.88
SRR6202358	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	69.60
SRR6202259	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	69.26
SRR6202363	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	69.17
SRR6202346	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	68.92
SRR6202345	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	66.07
SRR6202343	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	65.72
SRR6202364	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	63.78
SRR6202211	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.05
SRR6202205	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	61.18
SRR6202210	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	61.07
SRR6202208	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	57.59
SRR6202206	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	57.30
SRR6202207	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	56.67
SRR6202209	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	56.55
SRR6202212	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	53.42
SRR6202357	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.33
SRR6202255	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	46.71
SRR6202237	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	46.15
SRR6202236	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	45.24
SRR6202235	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	44.51
SRR6202238	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	41.24
SRR6202203	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.82
SRR6202254	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	39.14
SRR6202204	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.11
SRR6202257	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.38
SRR6202239	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.36
SRR6202256	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.12
SRR6202240	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	33.64
SRR6202307	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	131.38
SRR6202309	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	119.12
SRR6202282	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	117.54
SRR6202283	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	116.04
SRR6202308	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	108.46
SRR6202310	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	102.51
SRR6202306	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	102.13
SRR6202304	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	99.37
SRR6202305	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	97.63
SRR6202285	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	96.78
SRR6202284	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	96.25
SRR6202349	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	90.43
SRR6202303	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	88.53
SRR6202342	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	80.36
SRR6202341	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	71.12
SRR6202262	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	69.90
SRR6202348	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	67.91
SRR6202339	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	67.37
SRR6202340	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	66.88
SRR6202263	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	66.52
SRR6202354	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	65.75
SRR6202276	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	62.01
SRR6202277	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	61.76
SRR6202338	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	60.07
SRR6202337	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	59.62
SRR6202347	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	58.69
SRR6202352	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	55.86
SRR6202280	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	55.78
SRR6202278	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.60
SRR6202355	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.80
SRR6202350	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.21
SRR6202279	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	49.33
SRR6202281	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.33
SRR6202351	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	46.60
SRR6202356	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	45.95
SRR6202353	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	0.00

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.