Gene detail

Detailed information of KXJ27682.1 in Exaiptasia diaphana

Genomic Location: LJWW01000018.1:630746...641782
NR annotation: XP_020895487.1, prolyl endopeptidase isoform X1 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

KXJ27682.1

ATGGCCATGGCGGAAATTAAGTTGTCTCGATTTCATTATGATGAAAGATCTCAACTTTGGCTGGAACCATTCTCAGAGCTCATCAATGGCTTGTTCCCCATAGAACAAGTGTATGGAGACTGGAATTGGTGGCATGCTGAGAGAGAAGCAAGACTTTTATTTAATCCAGAATCCCTCTGTTCTTCCTCTTCGTCTTACTTACCAACTGGTAGCCGAGCCGAGGGTTTTTGCATTCCTCGGCTCCTGTATTCAGATCGTGAAGGAGATGTTCCYTTACATGAAAGGAAATYCTGGACACCAGATTTAGATGAGATGAAAGTTGAAGAATGCTKCATCGAGGATGARAACAATAAATCAATCGCTATTTTCACACCAGAACACGTGTCAGATGATCCTAGGTATGTGCATCTAAGATTCACCGACCAATGGAAAGAGGCAAAACCCAGGTATAAGAATGCAGAATTTGTCAACCATACTTTTTTGGTACCCTCCAATTGGTTTCCTGGTTTTGTTGGTCAAGGGTGGACATACGAAATGCATGGTCCAGTGCGAAAACTTCAACGAGCACAGAACGATTCTGGCTTTGTCGCCGGTATTGAGGAAGACCAGACTGGCGTCTTTAAGTATCCTTTAGCATGGCCTAAAGAGGCAATGGAGTGGATTATTCGCCCAAGACAGAATGCCTGGCCATCGCCTGAACTTCTTCAAAGTATAMTTGAATCGGGATGTCACTTGGCTCCCGTTGGAAGAGGAAAGCGCCAGAAAGAGTTACTGGAGTACATTGATTATGATAAAAGCCCTGCGCAAGCATCAACATCTTCTAGAAATGATCAAGACAGCCAAGACCTGAGCAAAATGGACGAAACTGAGTGGAGGTTGTCTTTCTCTGTTGCTAAAAACAAACTCGGCGAAAGTGTATCTCCTGTGCAACGCCATGTTCTCGTGTTCCTCAAAATGATCAAAAAGGTTTATTTCCCAGACGTGATATCTTCATATCACTTGAAGAACTTACTATTTTGGGAAATTGAAAAGCAAGACAAGTCATTTTGGATGGAAAGTAATATGTCGAGCTGTTTGTTGTTAATTCTGGATCGATTGCAAAAGAGTGTGGAAGAAGGTTATCTCCCTCACTATATAATCCCAACCAGCAACCTATTCTGTTCAGAGGATCCTTCTGAACTTACTCAAGCAGCTGCAGTCATCTCTGACGTGAGAGTCAATATTTTGCCCAAAACGATAAGCTTGCTGAAAAGATGTTTTTCAATGACTTATCTCACACAAACGTTCATGAAAGACCTGAAGGATTTGGAAACGCTAGCTGAGAAACTACATGACAAATCGCTGAAAGAAGATGACGTGGCTGAGCTAACGAGATTGCTGCTTGGCGTCTTTATCGAGAAGAGTGGAGAAGTGCTAGAGGCGATTTACCAAAGTCAACCAGAAGAAGAACAGGAAAATGCCGAAACGATCAAGCAGATGTTGCTTGTTCCTTTGAGTGCGTATCAATCACTTCTGGCAAGAAATTTATGTAAGGCATGGTATCTAAAACACAACAAAACCAAAGAAAACCCATCAAGCCATGATTTTGTGTCATTTGTAAAAGATGAAGTGAAGAAATTGCCCCTTGATGACACGTTTTTTGACTTAACCAACTTGTATTTCACGGAAGCCAGAGAAAATAGAGATATGTCGCTTATGATTCCTTACACTTCTGCCATGAAAAACACAAAGGAATCTTACAGAAAAGTTGCATGGAAGCAAGTTGGGGATGCCCAGAACAAGTTAGACCAGGTAATGGCAGGAATTACCAAAACTGACCTGAAAGAAATATCAAAACGTCTTGAAGAAAAATTTAAATGTCAGCTGGACAGTGTGACGACTGAAGGTATCAGAGCTGCAATAGACGAAGAACTTCAATTATTAGTTTACAGGAAAAAGTTGTCAGGAATGATGGCTGATTCTTGTACAATAACTTATCCTTCTGTACGGMGAGATGAGACGATTATTGACGACTACCACGGCCACAAAGTTCCCGATCCTTATGCCTGGCTAGAAGACCCTGACTCCAAAGAAACGAAAGAGTTTGTCCATGAAGAGAACGAAGTCACTACCAAGTATTTGGCGGAGTGTGATATTCGAGATCGCTTCAAAAACCGTATGACTGAACTGTGGGACTATCCCAAATATGGGTGTCCATTCAAGGAAGGACCACGTTATTTCTATTTCTACAACTCAGGATTACAAAACCAAAGCGTGATGTATGTCCAGAATAGCCTCAAGGAAGAAGCCAAAGTGTTTTTAGATCCAAATAAACTCTCAGATGATGGGACAACTGCTCTTGCTGGCAGGACATTCACTGAGGATGGGGAACTGTTTGCTTATTCACTAAGTGCAAAAGGATCTGATTGGGTTACTATCAAGTTCATGAAAGTGGAAGGAGCTGTTCAGCTGCCTGATACTCTAGAAAAAGCCAAGTTCACAAGCATGTCTTGGACCCATGACAATAAAGGATTGTTTTACAATCAATATCCCAACCATACAACTAAAGCTGATGGCACAGAAACAGACTCTAATCTTGATCAAAAGCTCTACTACCACTACCTGGGAACCAGTCAAAGTGAGGATATTTTATGCTGTGAATTTCCAGAAAAACCTAAGTGGCAAGTGGGAGGTCAAGTAAGTGATTGTGGAAACTATCTTCTAATCACTCCAAGGGAAGGTTGTGAACCAGTGAAYAGGCTCTTTTATTGTGACCTGAAAACTCTTGGTGCAATCAAAGAAAAGCTACCCTATGTTAAGRTTGTTGACAACTTTGATGCTGAATATGAGTATATAACAAACCAAGGCACRATGTTCACTTTCAAGACAAACCTGAACTCACCAAGATACAAGTTGATCAATATAGACTTGAACAACTACCAACAGGACAACTGGACAACCCTAATACCACAGGATGATCTAGATGTACTAGAGTGGGCTTCCTGTGTTAAGCAAAACTTGCTTGTACTGGGTTATCTTCATGATGTCAAGAGTGTCCTTCACTTGCACAGTCTGGAAACTGGARAACGTCTCATGACTTTTCCTCTTGACATAGGCTCAGTTGTGGGATTTTCAGGGCATAAGCGCCAKTCTGAGATATTTTACCAATTTACCTCTTTTCTCACCCCTGGAGTCATATACCATTGTGACTTGGCAGAAGAAAAGCCTCARTCAAAGGTTTTTCGTGAAATAGTTGTCAAAGGCTTTGATTCCAGTTTGTATCAAACGGACCAAGTGTTTTTCAATAGYAAAGATGGAACAAAGATCCCAATGTTTATTGTTCACAAGAAGGGAATCAGTCTGGACTCCAGTCATCCTGCCTTCTTGTATGGCTATGGAGGGTTTAGTATCTCAATAACCCCGTCATTYAGTGTGTCAAGGATCATGTTCATCCATAATCTTGGTGGTATTCTTGCCATTGCTAACATCAGAGGAGGACAAGAATATGGTGAAACATGGCACAAAGCTGGTATTTTTGGCAACAAACAGAATGTATTTGATGATTTTCAGTTTGCATCTAAATATCTGATTGACCAGAAGTACACTTCACCAAAAAAGCTTACAATATGTGGAGGATCGAATGGAGGTCTGTTAGTGACAGCATGCATCAATCAAAGGCCGGACTTGTTTGGTTGCGCCATTTCTCAAGTACCGGTGACAGACATGCTCAAGTTTCATAAGTTCACTATAGGACATGCATGGACAACAGATTTTGGATGTGCTGACAAGAAAGAAGAATTTGAATGGCTCATCAAATACTCGCCGCTCCACAACGTCAAAATACCCGACAATGGTGCACAGTACCCCGCGGTTTTGTTGCTAACCGCTGACCATGACGACCGTGTTGTTCCCCTTCATTCGTTCAAGTACATTGCAGAACTCCAACATGTCATGGGCCACTTAGAATACCAGAAAAATCCATTGTTGATCAGAATTGATACAGAAGCTGGTCATGGKTTTGGTAAACCAACTGCTAAACTGATTGAAGAATATTCAGATATCTTTGCATTCATCGCAAGAAATGTTGGTGCAACATGGCGTGATTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48147	Prolyl endopeptidase OS=Homo sapiens OX=9606 GN=PREP PE=1 SV=2
P23687	Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREP PE=1 SV=1
Q9QUR6	Prolyl endopeptidase OS=Mus musculus OX=10090 GN=Prep PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002666 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02897 all species →	Peptidase_S9_N	Prolyl oligopeptidase, N-terminal beta-propeller domain	Repeat	Interproscan
PF20266 all species →	Mab-21_C	Mab-21 protein HhH/H2TH-like domain	Domain	Interproscan
PF00326 all species →	Peptidase_S9	Prolyl oligopeptidase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR024810 all species →	Family	MAB21L/Cyclic GMP-AMP synthase-like receptor	Interproscan
IPR023302 all species →	Domain	Peptidase S9A, N-terminal domain	Interproscan
IPR046906 all species →	Domain	Mab-21-like, HhH/H2TH-like domain	Interproscan
IPR029058 all species →	Homologous_superfamily	Alpha/Beta hydrolase fold	Interproscan
IPR051167 all species →	Family	Prolyl oligopeptidase and macrocyclase	Interproscan
IPR001375 all species →	Domain	Peptidase S9, prolyl oligopeptidase, catalytic domain	Interproscan
IPR002470 all species →	Family	Peptidase S9A, prolyl oligopeptidase	Interproscan
IPR002471 all species →	Active_site	Peptidase S9, serine active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42881 all species →	PROLYL ENDOPEPTIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004252 all species →	Molecular Function	serine-type endopeptidase activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0070012 all species →	Molecular Function	oligopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008236 all species →	Molecular Function	serine-type peptidase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01322	PREP; prolyl oligopeptidase	EC:3.4.21.26	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ27682.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples

68TPM > 0

2Conditions

68.8Max TPM

43.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole animal · aposymbiotic	36	34	38.73	61.61
whole animal · symbiotic	36	34	47.25	68.82

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6202344	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	61.61
SRR6202234	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	52.21
SRR6202242	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	50.93
SRR6202233	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	50.26
SRR6202261	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	49.76
SRR6202260	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	49.56
SRR6202357	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.98
SRR6202212	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.66
SRR6202241	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.65
SRR6202259	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	46.00
SRR6202211	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	44.95
SRR6202258	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	44.16
SRR6202209	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	43.79
SRR6202210	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	43.20
SRR6202207	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	41.42
SRR6202343	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.72
SRR6202206	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.67
SRR6202255	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.77
SRR6202346	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.33
SRR6202254	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.30
SRR6202358	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.14
SRR6202236	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.03
SRR6202237	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.28
SRR6202238	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.04
SRR6202208	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	36.00
SRR6202363	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.99
SRR6202205	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.91
SRR6202235	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	34.70
SRR6202203	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	33.47
SRR6202256	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	32.51
SRR6202239	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	32.03
SRR6202257	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	30.34
SRR6202204	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	30.16
SRR6202240	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	28.65
SRR6202345	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	0.00
SRR6202364	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	0.00
SRR6202348	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	68.82
SRR6202308	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	58.79
SRR6202342	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	57.96
SRR6202306	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	57.10
SRR6202285	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	54.86
SRR6202305	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	54.22
SRR6202310	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	54.00
SRR6202284	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.62
SRR6202309	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.42
SRR6202307	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.11
SRR6202352	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	52.74
SRR6202282	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	52.68
SRR6202283	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	52.60
SRR6202281	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	52.24
SRR6202303	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.58
SRR6202304	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.38
SRR6202347	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.13
SRR6202340	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.32
SRR6202262	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	49.63
SRR6202351	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	49.02
SRR6202280	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	48.81
SRR6202339	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	48.19
SRR6202354	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.71
SRR6202263	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.63
SRR6202341	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	46.75
SRR6202338	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	45.66
SRR6202276	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	44.99
SRR6202337	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	43.96
SRR6202278	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	43.44
SRR6202277	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	42.94
SRR6202355	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	42.45
SRR6202279	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	41.69
SRR6202356	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	40.81
SRR6202350	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	36.81
SRR6202349	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	0.00
SRR6202353	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	0.00

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.