Gene detail

Detailed information of KXJ27883.1 in Exaiptasia diaphana

Genomic Location: LJWW01000016.1:1032397...1058635
NR annotation: KXJ27883.1, Rho-associated protein kinase 2 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

KXJ27883.1

ATGGAGAAGCGAAAAGAGTTGCTGGAGAGAAAAGTCCGAGACCCAAGGAGTGAGCTATTTGTTGACGGGCTTTTGGATGGTATAGAGGCGCTTGTGAACGATTGTAACTACCCACAGATTCGTCGGAACAAGAATGTTGAGAACTTCGTACAACGGTATGAGGGGCCGTCGAGAATTATCCAAGATAACAGATTACGGTCGAGCGATTTTCAMATTCTCAAAGTAATCGGACGTGGAGCTTTTGGCGAAGTTCAGTTGGTTCGGTCAAAGTATACCAAGAAGGTTTACGCTATGAAGTTATTGAGCAAGTTTGAAATGATTAAAAGGTCTGACTCGGCTTTCTTCTGGGAGGAGCGAGAGATCATGGCTCATTCTAACAGTGATTGGATTGTAAAGCTTCATTATGCCTTCCAAGATGAAAAATATCTTTACATGGTCATGGACTACATGGCAGGTGGAGATCTTGTCAATCTCATGAGTAATTATGAAATCCCTGAGAAATGGGCCAAGTTCTATTGTGCCGAGGTTGTGCTGGCAYTGGATGCAATACATTCAATGGGATTTATACACAGGGATGTSAAGCCAGACAACATGTTATTAGATCGTGAAGGCCATTTGAAATTAGCMGATTTTGGAACTTGTATGAGAATGGATAAGGATGGGATGGTGAGGTCAGACACTGCTGTTGGAACCCCTGACTATATATCACCTGAGGTTCTCAAGTCCCAAGGAGGGGAAGGACATTATGGAAGAGAATGTGACTGGTGGAGTGTAGGAGTATTTTTATATGAAATGCTTGTTGGTGATACACCGTTTTATGCAGATTCTTTAGTTGGAACATATGGTAAAATTATGGATCACAAAAACTCACTACAGTTTCCAGAAGACATTGAGATGTCTGGTCAAGCTAAAAGCCTTATTAAAGCATTTCTWATAGACAGACAACAAAGACTTGGAACAACTGGCATCCATGAAATTCAACAGCATAAATTCTTCGTCAATACGGAATGGGACTGGAATAATATAAGAGAAGCAATCCCTCCAGTGGTTCCTGAGCTTATTGGTGATGATGACACTTCTAATTTTGATGAAATTCCTGAACCTGATGCAGGAGAAGAGTTCTTCCCAATACCCAAGGCATTTGCTGGTAACCATCTACCATTTATAGGATTCACATATTCGAAGGAAGCCAGGTGGACTGGTGGTGGTCYCCCAGCAGACGTCCTGGTAAGTGGGGATGGCCACACATATTCTAACCAGAACTCAAGTAAAGAGGCTGAAGCAGCAAAGCTTAAAATTCAACAACTTGAAAGTGACTTAGGAATTGCACTTACTTCTAAAGGAGATTTGGAAAACAATTTAAGAGCTGCCACTGCTAAGCTTGAGAAAGTGCTCAGAGAATTTGAGAGTGAGGCTGAAGGCCGTAGAAATACTGAGGCTGCAAATAGAGAATTAGAAAGAGATGCTGCTCAGATGAAATATGATCTTAGAGAGATCCAAAGAAAATTGGAATATGAAACTGATGTTAAAAGAAAGTATGAAGTCAAAGCCCAAGAACTTCAGGGACGTCTGGATGCAGAGCTTGATGCAAGAGACAAGATCTCTCAGTCATCACAAAATGTCCAAACCAAAATTACGTATTTAGAAAAACAGATTGCTGAATTGCAAGCAAACTTGAAGACTGAAAGTGATGGCCATGCAAAGAACAAAAAGGCTTTGGGAGATCTCCAAAAGTCATATGCAGTTCTTGAAAGATCATATGGAGACCTTCAGGAGAAGAACAGAGTACTAAGCGACCAGAAGTTATCGCTGGAAAGATCACATATCAAAGTTCAAGCTAGTTTAGAAGCTGAGTTCAACATGAGAGTCCAAGCGAACACTGCTAAAGCAGATCTTGAATCACAATATCAAGCAATCAAAGATGAATATGAACAACTCAAAGCAAGGACTGCTTCCGATGCACATTTACAACAGAAACTGCAACAAGATTTGATCAACCTTGAAAAGGCTAAAGCCAATACAGAGTTTGAACTGAAGTCATTACAGCAGAAGTTTGATCAAGCAACACTGGATTACAAGTCTCAAATATCGTCATTCATGACTGAAAAGAAGCGTTTGTCACTCACACTTGAGGAGCAGCACATTCAAGAACGAGTTGAGCAAAGTAAAACAATGGAAAGACTCAAGGTAGAACAAGAARTGAGGGCCAAGGCTGAAGCRGCTGCTGCTGAAGCAGAGAGAGCAAAGACTGTTATGGCTGCAGATTATAAGGATGTTACTCAGAAGTTTGAGAGAGTGAAAGAAGAACTCAAGGCTCTTCAAGAGAAGAGTGAGAACACCAATCATAAATTGATAGCTGAGTCTCAAAAAAGAGCGCAACTTGAAGGAGAACTTGAGGCTCGAACCCAAGAACTTGCAACAACCAAAAGTACAGAGAGTCAGATCCAAAAGCAAATGGAAAGTATATTGGAAGAAAAAAGGCAACTTGAAGAAGGTTATTCTAAATTAAAGAGTACAAGTGCCATGGATGACTTACAACTAAAGGAATTACAAGATCAGCTTGAAGCAGAACAGTATTTCTCAACCTTGTACAAGACCCAAGTCAAGGAACTAAGAGAAGAGGTTGATGAGAAAAGTAAACATGTACAGGTGTTACAAAAGAACATAACACAATTACAAGAAGAAAGGGAATCCCTTGCTGCTCAGTTAGAACTCACTTTTACCAAAGCTGACTCTGAACAGCTTGCTCGTTCTATTGCTGAAGAYCAGTACTTAGACTTGGAAAAAGAAAAGACGATGATAGAATTAGAAGTCAAAGAACTGATTGCAAGACACAAGAGTGAAATAGTGGACAAGGCAGCACAGATATCACAACTAGAAGAYCTCAATCAACAGCTGACATCCAATCTTGATCAGAAAGTTCACGAGAAGGAGGATTTGAATAGTCAGATCAACAGTATACAGGCTGAACTTGACAAGGCCAAGGAGGAAAGCAAAGATGTGGAAAGTGCAACAGAACAGCTGAAAAAGCAACTTCATAGTGAAAAAATTCTCAAAACTCAGGCAGTAAATAAACTTGCRGAGATCATGAATCGTAAAGACTTTGGTAAAGACAATCAAAAGAAAAACAAGGTTTCGTCAGTAGAACTAAGAAAGAAGGAGAAAGAGTGTAAAAAACTGCACCAGGAATTAGCACAGGAGCGTGAAAAGTATGCACAGATGACCTCAAAATACCAAGGACAGGTTGCTGAGTCTACTGCGAATCTACAAATGGAAACAGAACAGCGACAAAAGATGCAGATGGAGTTAGAGTCCAAYGATCTGATGATAGAACAACTACAAAATAAATTAAAGAATGCAACGGTGAATACACCTACTGTTACAGAAGATCCTAACCACTCCATATCATTGAATATGAACAAAGAAGGTTGGATATCTGTACCAAATAGACAGAATATTAAAAAATATGGCTGGAGAAAACAGTATCTTGTGATTAGTAGCCGTAAACTCTTTTTTTACAATTCCGATGCTGATCACAGAAATAGTTCAACGCCTATCATGATTTTAGATATTAGTAAATTATTTCACGTCCGGTCTGTGACGCAAGGCGATGTAATACGCGCAGACGCTAAAGACATTCCTAGAATATTCCAGATTCTTTACGCTAATGAGGGCGAAAGTATAAATCCCAATGAGAAAGAAAAACTAGAAGACCAGCAGTCTCCAGAGGAGAAAATGGCTGCAATCAACTACATGCGACATCAATTTATCCCAATGCATTTCCARATGCCAACTAATTGTGACTCGTGTAGTAAACCATTATGGCATATGTTTAAACCTCCGCCTGCACTCGAATGTCGACGTTGTCATCTTAAGTGTCATAAGGATCATGTGGATCGTGAAGAAGCTTGTATTCAATCGTGTAACGTGAACGCAGACCTGATTTCAGCCAAGGACTTATTAGTTCTGGCAGGTTCGCCAGAGGAACAGAAGGAATGGGTCTTATACCTCAGCAAGAAAATAGTTAAAAAACAACCCAAATCAAAAAGTTCGTCAGTTCGACACCCCGGCGACGATCATATTATGAGAAGGCATATGGGTGATCGTTCCATGTCGAGCTCATCGCAACGCGTTCAACCGCCTCAACCTCAACGATCGACATCCATGTCTTCACAGCTCAGACACAAGACATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75116	Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4
O77819	Rho-associated protein kinase 1 OS=Oryctolagus cuniculus OX=9986 GN=ROCK1 PE=1 SV=1
Q62868	Rho-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Rock2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002895 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08912 all species →	Rho_Binding	Rho Binding	Coiled-coil	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR000961 all species →	Domain	AGC-kinase, C-terminal	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR002219 all species →	Domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR015008 all species →	Domain	ROCK, Rho binding domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR050839 all species →	Family	Rho-associated Serine/Threonine Kinase	Interproscan
IPR046349 all species →	Homologous_superfamily	C1-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22988 all species →	MYOTONIC DYSTROPHY S/T KINASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0031267 all species →	Molecular Function	small GTPase binding	Interproscan
GO:0000281 all species →	Biological Process	mitotic cytokinesis	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0007266 all species →	Biological Process	Rho protein signal transduction	Interproscan
GO:0018107 all species →	Biological Process	peptidyl-threonine phosphorylation	Interproscan
GO:0030866 all species →	Biological Process	cortical actin cytoskeleton organization	Interproscan
GO:0031032 all species →	Biological Process	actomyosin structure organization	Interproscan
GO:0048598 all species →	Biological Process	embryonic morphogenesis	Interproscan
GO:0072518 all species →	Molecular Function	Rho-dependent protein serine/threonine kinase activity	Interproscan
GO:1901888 all species →	Biological Process	regulation of cell junction assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for KXJ27883.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ27883.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples

72TPM > 0

2Conditions

98.0Max TPM

54.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole animal · aposymbiotic	36	36	49.22	98.03
whole animal · symbiotic	36	36	58.88	94.87

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6202345	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	98.03
SRR6202343	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	68.52
SRR6202346	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	64.16
SRR6202233	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	63.81
SRR6202260	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.76
SRR6202261	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.68
SRR6202259	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	62.27
SRR6202344	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	61.65
SRR6202241	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	60.26
SRR6202258	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	59.23
SRR6202234	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	59.12
SRR6202242	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	57.31
SRR6202364	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	56.76
SRR6202358	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	55.70
SRR6202210	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	53.04
SRR6202212	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	49.13
SRR6202211	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.92
SRR6202205	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	47.05
SRR6202209	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	45.85
SRR6202357	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	45.46
SRR6202363	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	45.29
SRR6202208	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	44.73
SRR6202206	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	42.65
SRR6202207	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	41.45
SRR6202254	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.49
SRR6202255	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.26
SRR6202238	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	40.00
SRR6202235	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.51
SRR6202237	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	38.49
SRR6202236	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	37.71
SRR6202256	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	31.09
SRR6202257	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	30.74
SRR6202204	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	30.56
SRR6202203	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	29.89
SRR6202239	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	29.63
SRR6202240	whole animal · aposymbiotic	whole animal	not recorded	aposymbiotic	SRP120942	29.57
SRR6202342	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	94.87
SRR6202285	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	88.52
SRR6202284	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	87.73
SRR6202304	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	87.62
SRR6202306	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	87.10
SRR6202305	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	85.16
SRR6202303	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	84.89
SRR6202310	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	68.63
SRR6202308	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	67.85
SRR6202282	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	65.55
SRR6202283	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	64.10
SRR6202307	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	62.58
SRR6202341	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	61.25
SRR6202309	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	60.78
SRR6202263	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	58.74
SRR6202339	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	57.48
SRR6202262	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	54.93
SRR6202340	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	54.06
SRR6202281	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.67
SRR6202347	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	53.31
SRR6202280	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.84
SRR6202352	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	51.36
SRR6202338	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.85
SRR6202276	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.85
SRR6202350	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.29
SRR6202351	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.16
SRR6202337	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	50.00
SRR6202279	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	48.74
SRR6202278	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.87
SRR6202356	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.65
SRR6202277	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	47.63
SRR6202355	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	45.97
SRR6202353	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	40.70
SRR6202349	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	30.25
SRR6202354	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	28.56
SRR6202348	whole animal · symbiotic	whole animal	not recorded	symbiotic	SRP120942	28.16

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.