Gene detail

Detailed information of OS493_000008-T1 in Lophelia pertusa

Genomic Location: scaffold_1:109919...123494
NR annotation: KAJ7394206.1, Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O60476	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1
P39098	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Mus musculus OX=10090 GN=Man1a2 PE=1 SV=1
P45700	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Mus musculus OX=10090 GN=Man1a1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001783 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01532 all species →	Glyco_hydro_47	Glycosyl hydrolase family 47	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050749 all species →	Family	Glycosyl Hydrolase Family 47	Interproscan
IPR036026 all species →	Homologous_superfamily	Seven-hairpin glycosidases	Interproscan
IPR001382 all species →	Family	Glycoside hydrolase family 47	Interproscan
IPR012341 all species →	Homologous_superfamily	Six-hairpin glycosidase-like superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11742 all species →	MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000139 all species →	Cellular Component	Golgi membrane	Interproscan
GO:0004571 all species →	Molecular Function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:1904382 all species →	Biological Process	mannose trimming involved in glycoprotein ERAD pathway	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01230	MAN1A_C, MNS1_2; mannosyl-oligosaccharide alpha-1,2-mannosidase	EC:3.2.1.113	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_000008-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

71.9Max TPM

23.5Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	14.65	24.39
polyp at pH7 6	18	18	15.63	24.85
coral polyp · control treatment	16	16	29.09	71.87
coral polyp · oil and dispersant treatment	16	16	43.81	70.10
coral polyp · oil treatment	16	16	23.72	48.17
coral polyp · dispersant treatment	16	16	25.40	68.91
Polyp	10	10	8.72	20.78

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.39
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	23.40
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	20.45
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.26
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.58
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.99
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.78
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.41
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.43
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.84
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.05
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.80
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.70
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.65
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.01
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.23
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.36
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.30
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	24.85
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	24.73
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.51
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.69
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.75
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.24
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.23
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.86
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.74
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.43
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.02
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.95
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.15
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.50
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.91
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.52
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.03
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.32
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	71.87
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	41.38
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	37.86
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.84
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	35.91
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	32.69
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.27
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	26.19
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.06
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.72
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.45
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.89
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	22.48
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.92
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.29
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.68
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	70.10
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	69.62
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	59.99
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	56.31
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	55.09
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	50.68
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.24
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	45.04
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	41.56
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	37.94
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	36.99
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	36.87
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	33.34
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	32.43
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	18.62
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.22
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	48.17
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	37.54
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	36.80
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	33.55
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.98
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	24.91
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	24.78
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	23.41
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.46
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	20.41
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.25
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.93
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.89
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.49
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.49
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.45
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	68.91
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	39.66
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	37.33
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	31.83
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	30.41
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.63
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	23.56
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	23.56
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	23.01
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	22.28
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	22.06
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.37
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	18.21
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.59
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.58
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.41
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	20.78
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	12.35
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	11.26
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	8.08
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	7.23
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	7.01
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	6.51
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	5.01
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	4.95
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	4.03

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.