Genomic Location: scaffold_3:1985978...2033331
NR annotation: KAJ7381337.1, putative phospholipid-transporting ATPase IF [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families
| CDS |
| OS493_001462-T1 |
| Transcript |
| OS493_001462-T1 |
| Protein |
| OS493_001462-T1 |
| UniProt accession | Description |
|---|---|
| Q9Y2G3 | Phospholipid-transporting ATPase IF OS=Homo sapiens OX=9606 GN=ATP11B PE=1 SV=2 |
| Q6DFW5 | Phospholipid-transporting ATPase IF OS=Mus musculus OX=10090 GN=Atp11b PE=1 SV=1 |
| Q9N0Z4 | Phospholipid-transporting ATPase IF (Fragment) OS=Oryctolagus cuniculus OX=9986 GN=ATP11B PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000534 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16209 all species → | PhoLip_ATPase_N | Phospholipid-translocating ATPase N-terminal | Family | Interproscan |
| PF00122 all species → | E1-E2_ATPase | E1-E2 ATPase | Family | Interproscan |
| PF16212 all species → | PhoLip_ATPase_C | Phospholipid-translocating P-type ATPase C-terminal | Family | Interproscan |
| PF13246 all species → | Cation_ATPase | Cation transport ATPase (P-type) | Family | Interproscan |
| PF00702 all species → | Hydrolase | haloacid dehalogenase-like hydrolase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR023214 all species → | Homologous_superfamily | HAD superfamily | Interproscan |
| IPR023298 all species → | Homologous_superfamily | P-type ATPase, transmembrane domain superfamily | Interproscan |
| IPR032631 all species → | Domain | P-type ATPase, N-terminal | Interproscan |
| IPR023299 all species → | Homologous_superfamily | P-type ATPase, cytoplasmic domain N | Interproscan |
| IPR044492 all species → | Domain | P-type ATPase, haloacid dehalogenase domain | Interproscan |
| IPR006539 all species → | Family | P-type ATPase, subfamily IV | Interproscan |
| IPR032630 all species → | Domain | P-type ATPase, C-terminal | Interproscan |
| IPR018303 all species → | PTM | P-type ATPase, phosphorylation site | Interproscan |
| IPR001757 all species → | Family | P-type ATPase | Interproscan |
| IPR008250 all species → | Homologous_superfamily | P-type ATPase, A domain superfamily | Interproscan |
| IPR036412 all species → | Homologous_superfamily | HAD-like superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24092 all species → | PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000166 all species → | Molecular Function | nucleotide binding | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0045332 all species → | Biological Process | phospholipid translocation | Interproscan |
| GO:0140326 all species → | Molecular Function | ATPase-coupled intramembrane lipid transporter activity | Interproscan |
| GO:0000287 all species → | Molecular Function | magnesium ion binding | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0015914 all species → | Biological Process | phospholipid transport | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005215 all species → | Molecular Function | transporter activity | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K26934 | ATP11; phospholipid-transporting ATPase | EC:7.6.2.1 | Efferocytosis | ko04148 | deepkoala |
Transcript abundance of OS493_001462-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| polyp at pH7 9 | 18 | 18 | 19.12 | 25.42 | |
| polyp at pH7 6 | 18 | 18 | 17.71 | 25.52 | |
| coral polyp · control treatment | 16 | 16 | 25.61 | 37.22 | |
| coral polyp · oil and dispersant treatment | 16 | 16 | 20.64 | 29.78 | |
| coral polyp · oil treatment | 16 | 16 | 21.84 | 34.81 | |
| coral polyp · dispersant treatment | 16 | 16 | 16.94 | 32.67 | |
| Polyp | 10 | 10 | 24.63 | 40.34 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11359520 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 25.42 |
| SRR11359521 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 25.05 |
| SRR11359523 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 24.08 |
| SRR11359522 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 23.37 |
| SRR11359518 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 20.84 |
| SRR11359511 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 20.21 |
| SRR11359510 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 20.10 |
| SRR11359498 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 19.87 |
| SRR11359519 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 19.70 |
| SRR11359499 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 19.31 |
| SRR11359497 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 18.77 |
| SRR11359496 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 18.48 |
| SRR11359495 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 18.45 |
| SRR11359494 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 17.02 |
| SRR11359509 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 14.65 |
| SRR11359508 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 14.38 |
| SRR11359507 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 13.03 |
| SRR11359506 | polyp at pH7 9 | not recorded | not recorded | not recorded | - | 11.45 |
| SRR11359501 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 25.52 |
| SRR11359500 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 23.07 |
| SRR11359528 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 22.08 |
| SRR11359515 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 21.89 |
| SRR11359514 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 21.72 |
| SRR11359529 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 21.20 |
| SRR11359516 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 18.85 |
| SRR11359526 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 18.82 |
| SRR11359527 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 18.81 |
| SRR11359505 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 17.36 |
| SRR11359504 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 17.19 |
| SRR11359517 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 17.01 |
| SRR11359512 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 16.07 |
| SRR11359502 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 15.20 |
| SRR11359503 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 14.80 |
| SRR11359513 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 13.80 |
| SRR11359524 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 8.96 |
| SRR11359525 | polyp at pH7 6 | not recorded | not recorded | not recorded | - | 6.40 |
| SRR16705960 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 37.22 |
| SRR16705942 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 34.79 |
| SRR16705990 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 32.71 |
| SRR16705965 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 32.50 |
| SRR16705971 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 31.84 |
| SRR16705973 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 31.70 |
| SRR16705972 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 31.62 |
| SRR16705974 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 29.36 |
| SRR16705946 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 25.27 |
| SRR16705957 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 24.62 |
| SRR16705991 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 20.79 |
| SRR16705970 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 18.73 |
| SRR16705943 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 17.74 |
| SRR16705989 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 15.82 |
| SRR16705975 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 15.32 |
| SRR16705992 | coral polyp · control treatment | coral polyp | polyp | control treatment | SRP344271 | 9.69 |
| SRR16705995 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 29.78 |
| SRR16705982 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 28.30 |
| SRR16706004 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 27.83 |
| SRR16705993 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 26.72 |
| SRR16705977 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 24.04 |
| SRR16706005 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 22.57 |
| SRR16705945 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 20.69 |
| SRR16705979 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 19.52 |
| SRR16705997 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 19.03 |
| SRR16705976 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 18.70 |
| SRR16705944 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 17.93 |
| SRR16705948 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 16.91 |
| SRR16705978 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 16.51 |
| SRR16705996 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 15.73 |
| SRR16705947 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 15.09 |
| SRR16705994 | coral polyp · oil and dispersant treatment | coral polyp | polyp | oil and dispersant treatment | SRP344271 | 10.88 |
| SRR16705999 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 34.81 |
| SRR16705998 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 34.42 |
| SRR16706000 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 31.13 |
| SRR16706001 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 27.87 |
| SRR16705981 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 26.17 |
| SRR16705951 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 22.75 |
| SRR16705949 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 22.68 |
| SRR16705983 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 22.00 |
| SRR16705984 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 19.85 |
| SRR16705950 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 19.12 |
| SRR16705961 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 19.10 |
| SRR16705980 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 17.89 |
| SRR16705952 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 16.56 |
| SRR16705963 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 12.56 |
| SRR16705964 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 12.38 |
| SRR16705962 | coral polyp · oil treatment | coral polyp | polyp | oil treatment | SRP344271 | 10.11 |
| SRR16705958 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 32.67 |
| SRR16706002 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 28.19 |
| SRR16705959 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 27.67 |
| SRR16706003 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 26.96 |
| SRR16705954 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 21.60 |
| SRR16705986 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 18.76 |
| SRR16705955 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 16.98 |
| SRR16705967 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 15.61 |
| SRR16705968 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 15.18 |
| SRR16705988 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 14.19 |
| SRR16705956 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 13.74 |
| SRR16705966 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 13.04 |
| SRR16705969 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 11.04 |
| SRR16705987 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 6.61 |
| SRR16705985 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 5.61 |
| SRR16705953 | coral polyp · dispersant treatment | coral polyp | polyp | dispersant treatment | SRP344271 | 3.29 |
| SRR23025708 | Polyp | not recorded | not recorded | not recorded | - | 40.34 |
| SRR23025711 | Polyp | not recorded | not recorded | not recorded | - | 39.15 |
| SRR23025710 | Polyp | not recorded | not recorded | not recorded | - | 36.71 |
| SRR23025709 | Polyp | not recorded | not recorded | not recorded | - | 29.21 |
| SRR23025713 | Polyp | not recorded | not recorded | not recorded | - | 28.20 |
| SRR23025712 | Polyp | not recorded | not recorded | not recorded | - | 21.42 |
| SRR7746669 | Polyp | not recorded | not recorded | not recorded | - | 19.76 |
| SRR7746666 | Polyp | not recorded | not recorded | not recorded | - | 13.57 |
| SRR7746667 | Polyp | not recorded | not recorded | not recorded | - | 11.76 |
| SRR7746668 | Polyp | not recorded | not recorded | not recorded | - | 6.15 |
Source: CnidoSite RNA-seq expression matrices (LPERT_TPM,
StringTie quantification over 110 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Lophelia pertusa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 22 | OS493_018954-T1 | 0.840082301373114 |
| Negatively correlated | 0 | not in this network | - |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Lophelia pertusa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |