Detailed information of OS493_001793-T1 in Lophelia pertusa

Genomic Location: scaffold_4:1158711...1186551
NR annotation: KAJ7375061.1, Rho-associated protein kinase 2 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O75116Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4
O77819Rho-associated protein kinase 1 OS=Oryctolagus cuniculus OX=9986 GN=ROCK1 PE=1 SV=1
P70335Rho-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Rock1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002895 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00069
all species →
PkinaseProtein kinase domainDomainInterproscan
PF08912
all species →
Rho_BindingRho BindingCoiled-coilInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001849
all species →
DomainPleckstrin homology domainInterproscan
IPR017441
all species →
Binding_siteProtein kinase, ATP binding siteInterproscan
IPR015008
all species →
DomainROCK, Rho binding domainInterproscan
IPR000719
all species →
DomainProtein kinase domainInterproscan
IPR000961
all species →
DomainAGC-kinase, C-terminalInterproscan
IPR011993
all species →
Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR008271
all species →
Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR046349
all species →
Homologous_superfamilyC1-like domain superfamilyInterproscan
IPR002219
all species →
DomainProtein kinase C-like, phorbol ester/diacylglycerol-binding domainInterproscan
IPR050839
all species →
FamilyRho-associated Serine/Threonine KinaseInterproscan
IPR011009
all species →
Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR22988
all species →
MYOTONIC DYSTROPHY S/T KINASE-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0031267
all species →
Molecular Functionsmall GTPase bindingInterproscan
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan
GO:0004674
all species →
Molecular Functionprotein serine/threonine kinase activityInterproscan
GO:0000281
all species →
Biological Processmitotic cytokinesisInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005856
all species →
Cellular ComponentcytoskeletonInterproscan
GO:0007266
all species →
Biological ProcessRho protein signal transductionInterproscan
GO:0018107
all species →
Biological Processpeptidyl-threonine phosphorylationInterproscan
GO:0030866
all species →
Biological Processcortical actin cytoskeleton organizationInterproscan
GO:0031032
all species →
Biological Processactomyosin structure organizationInterproscan
GO:0048598
all species →
Biological Processembryonic morphogenesisInterproscan
GO:0072518
all species →
Molecular FunctionRho-dependent protein serine/threonine kinase activityInterproscan
GO:1901888
all species →
Biological Processregulation of cell junction assemblyInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for OS493_001793-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_001793-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples
110TPM > 0
7Conditions
37.2Max TPM
18.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
polyp at pH7 9 18 18 19.61 28.55
polyp at pH7 6 18 18 19.13 24.29
coral polyp · control treatment 16 16 21.06 37.19
coral polyp · oil and dispersant treatment 16 16 17.47 25.60
coral polyp · oil treatment 16 16 20.19 33.30
coral polyp · dispersant treatment 16 16 18.35 29.62
Polyp 10 10 13.31 20.77

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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