Gene detail

Detailed information of OS493_002231-T1 in Lophelia pertusa

Genomic Location: scaffold_4:7310831...7316132
NR annotation: KAJ7375458.1, hypothetical protein OS493_002231 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q3B7L5	Folliculin OS=Bos taurus OX=9913 GN=FLCN PE=2 SV=1
Q8NFG4	Folliculin OS=Homo sapiens OX=9606 GN=FLCN PE=1 SV=1
Q8QZS3	Folliculin OS=Mus musculus OX=10090 GN=Flcn PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005183 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF11704 all species →	Folliculin	Vesicle coat protein involved in Golgi to plasma membrane transport	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037521 all species →	Domain	Folliculin/SMCR8, tripartite DENN domain	Interproscan
IPR021713 all species →	Family	Folliculin	Interproscan
IPR037520 all species →	Domain	Folliculin/SMCR8, longin domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR31441 all species →	FOLLICULIN FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000122 all species →	Biological Process	negative regulation of transcription by RNA polymerase II	Interproscan
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0030511 all species →	Biological Process	positive regulation of transforming growth factor beta receptor signaling pathway	Interproscan
GO:1904263 all species →	Biological Process	positive regulation of TORC1 signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for OS493_002231-T1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_002231-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

80.6Max TPM

29.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	26.40	33.22
polyp at pH7 6	18	18	26.53	35.86
coral polyp · control treatment	16	16	28.88	44.65
coral polyp · oil and dispersant treatment	16	16	49.61	80.61
coral polyp · oil treatment	16	16	28.03	44.50
coral polyp · dispersant treatment	16	16	20.58	38.87
Polyp	10	10	19.84	37.15

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	33.22
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	32.74
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	32.45
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	31.74
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	31.45
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	30.22
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.50
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.06
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.75
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.21
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	27.89
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	25.49
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	24.70
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.14
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.50
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.96
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.77
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.36
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	35.86
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.86
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.01
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	33.38
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.81
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.44
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	30.42
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	29.11
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	28.45
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	27.69
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.85
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.25
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.89
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.71
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.18
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.66
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.32
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.63
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	44.65
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	39.23
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	38.57
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	34.76
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	31.46
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.87
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.84
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	30.55
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	29.07
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.79
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	25.06
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.35
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	24.14
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	19.89
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	18.80
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.11
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	80.61
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	69.33
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	68.78
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	58.97
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	58.01
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	55.69
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	50.75
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.72
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.61
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	44.75
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	39.99
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	38.20
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	36.40
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.99
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	31.04
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	26.93
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	44.50
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	37.44
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	37.37
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	35.12
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	34.29
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	33.73
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	30.86
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	30.22
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	27.06
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	25.64
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	23.16
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.85
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	22.15
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.84
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.01
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.20
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	38.87
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	34.15
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	26.08
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	25.00
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	24.49
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.26
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	21.09
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.92
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	20.28
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.66
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.69
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	16.30
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.87
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.07
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.06
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	3.49
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	37.15
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	24.76
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	23.80
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	23.66
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	19.74
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	18.49
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	17.64
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	13.38
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	11.67
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	8.09

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.