Gene detail

Detailed information of OS493_002428-T1 in Lophelia pertusa

Genomic Location: scaffold_5:2124930...2153591
NR annotation: KAJ7365712.1, Non-lysosomal glucosylceramidase [Desmophyllum pertusum]
Species abbreviation LPERT · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

OS493_002428-T1

ATGGCGGCATCTTCCTCGGGCGACGAGGGAAGTGAGCTGTCGCAACTTCTAATCCAGAGTGAGGATTCACTTCCTAAATACGGCTGGAGGGTGCATCTTGATAACACATTTTCACACAAGCCTCAACCATGTTATATGCCTCGATGGAGTCAAATACCACGGCTAATAGGTCTCGGATGGAGATTTATGAAATATGCTACAAGAGAGAGGAAGAACGGCAGAGTGCCGTTTATCGATCCATTTGCCACAAATCCTTGTCGCCAAGTATACGGGGTACCTCTTGGTGGAATAGGATGTGGCAGTATTGGACGAGGATGGAAGGGTGATTTTAACAGATGGCAGCTCACTCCAGGAATGTACAATTACAGCTATGTAGAGGCAAACCAGTTCATTGTTTGTGTGAGGAAAAAAGGAAGAACTACTTACCAGGCTGTTTTGTCGCCCAACCGTCCAAATGGTGTTCTTTGTGGACGTAGTTTACAGGGCTGGAACTGGGGGTTCAATGGTGCCCATGCCACATATCATGCTCTGTATCCACGTGCCTGGACCATTTATTACTTACCAGGACAAAACATCAGGCTCATTTGCCGTCAAGTTTCACCAGTGTTTCCTCACGATTACAAAGACACAAGTCTTCCTGTTGCTGTATTTATTTGGGAAGTGGAAAATAACAGTGATGAAGAAGTTGAAGTAGCAATCATGTTCACATTTCAAAACAGTGATGGAACTCCAAATGAAGTATTAAGTGGTCATTACAATGAACCATTCACATGTAAGATTGGTAGTCACTGCTCCATGGAGGATCATTCTGCAGATAAAAGAAATTCAGTTTTAACCAATGTATCTAGTGAAGTGACAGGAGTTCTTCTTCATCATGAACACCCAACGCAGCCGTACACGTTTGGGATTGCAGCCAAAGCCCAAAATCAGGCTGGAAATAGCGTAATCACTGTAACAACAAAAACTGCATTTGATGCACAAACACCCTGCAGAAGAGTATGGGAAGACTTAATGGATGATGGCAAACTCAACTCTACAACAGGATGTAGCGAGCCATCCAAACCAGAGCAGACTCTCTGTGCCGCAGTGGCAGCCACAACCAAGATACCATCAAAGGGCAAAGCAAAATTGGAGTTTGCTCTCTCATGGGATAATCCTGTTGTTCATTTTGGATCTTCAAAAAACAAACACTACAGGTTTTACACTCGTTTCTTTGGTCGTCATGGTGATGCAAGTAAAGGTCTTTGTTGTCATGCCCTGATGCGTTATCCTGAGTGGGAGTCCAAAATAGATGCTTGGCAAAAACCAATCTTACAAAATGATTCTTTGCCGTCATGGTACAAGTCAGCCCTCTTTAATGAGCTGTACTTTGTAGCTGATGGAGGAACAGTTTGGTTGGACGTGGAAGATGTCACAGACAACAAGACTCCCATTCCAGAATATGTTAAGGAACATGGTAGATTTGGGTATTTAGAAGGACATGAGTACAGAATGTACAATACGTATGATGTCCACTTCTATGCATCATTTGCTCTTGCCTTGCTATGGCCAAAGTTGCAACTGAGTCTTCAATACGACATAGCTCAGACTGTGAATCAGACAGACAGTCAGCTAACATTGACAATGATGAATGGACGGAACTGTCGGAGGAAAGTAGCTGGCTGTGTACCGCATGATGTAGGAGATCCAGCTGAGGAGCCATGGGAGAAAGTGAATGCCTATACTATTCACGACACAGCACAGTGGAAAGATCTTAACCTCAAGTTTGTTCTCCAGGTGTTTCGAGACTACAAGGCAACAAAGGACACTCAATATCTAAAGGACATGTGGCCTATTGCAAAGACAGTGATGAGTAAGACCATGGTGTATGACACAGATGGCGATGGCTTGATAGAAAACTCTGGCTTTGCAGATCAAACGTACGATGCATGGCCAGTCACAGGTCCAAGTGCTTATTGTGGAGGGCTGTGGTTAGCTGCTTTACGAGTCATGCAGGAAATAGCCAATGTGTTAGGAGTCCCAGATGAGGCTGTTAAATATGTGAACATCCTTAAAAGAGGAAAGAAGGCTTATCACGCTCTGCTGTGGAATGGAACATATTACAAGTACGATAGCAGCACCAATAAATACCACAACAGTATTATGGCCGATCAGATGGCAGGACAGTGGTATCTGAAGGCGTGTGAACTTGGACAGTCATCCAGTGATAGGGTGTTTCCAAGAGAGAATGTACTAAGTGCACTCAACACAGTGTATAAGTACAACGTGCTTCAGTTCCAAGATGGCGGTATGGGTGCTGTGAATGGCATGAGACCGAACGGCCAGGTTGACACGAGCAGTTTACAGGCGGAGGAGGTCTGGACCGGCATCACATACGCGGTGGCTGCTTCTATGATCCAGGAGGGTCTGGTGGAAGAGGGCTTCAAAACAGCCAGCGGCATTTACAACACTTGTTTTGAGAGACTGGGCATGGGTTTCCAGACTCCCGAGGCCATCGTTGCCAACGGCAACTTTCGCTCACTAGCGTACATGAGACCGCTGAGTATCTGGGCCATGCAGTGGGCGCTGGAAAGGAAGCACAAGCCTGCTGTTCATAACGATACCGCTGGCCCTAGCCGTGACTACTCTCAATGTAACGGATTTTGTAATGTCTCCAGTGATTCCTAA

Transcript

OS493_002428-T1

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9HCG7	Non-lysosomal glucosylceramidase OS=Homo sapiens OX=9606 GN=GBA2 PE=1 SV=2
Q5M868	Non-lysosomal glucosylceramidase OS=Rattus norvegicus OX=10116 GN=Gba2 PE=2 SV=2
Q69ZF3	Non-lysosomal glucosylceramidase OS=Mus musculus OX=10090 GN=Gba2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004343 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12215 all species →	Glyco_hydr_116N	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	Family	Interproscan
PF04685 all species →	DUF608	Glycosyl-hydrolase family 116, catalytic region	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR012341 all species →	Homologous_superfamily	Six-hairpin glycosidase-like superfamily	Interproscan
IPR024462 all species →	Domain	Glycosyl-hydrolase family 116, N-terminal	Interproscan
IPR006775 all species →	Domain	Glycosyl-hydrolase family 116, catalytic region	Interproscan
IPR008928 all species →	Homologous_superfamily	Six-hairpin glycosidase superfamily	Interproscan
IPR014551 all species →	Family	Beta-glucosidase GBA2-type	Interproscan
IPR052566 all species →	Family	Non-lysosomal glucosylceramidase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12654 all species →	BILE ACID BETA-GLUCOSIDASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0004553 all species →	Molecular Function	hydrolase activity, hydrolyzing O-glycosyl compounds	Interproscan
GO:0004348 all species →	Molecular Function	glucosylceramidase activity	Interproscan
GO:0006680 all species →	Biological Process	glucosylceramide catabolic process	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0008422 all species →	Molecular Function	beta-glucosidase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17108	GBA2; non-lysosomal glucosylceramidase	EC:3.2.1.45	Other glycan degradation	ko00511	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern

Expression trend for OS493_002428-T1 global co-expression network