Gene detail

Detailed information of OS493_002966-T1 in Lophelia pertusa

Genomic Location: scaffold_6:2756491...2769612
NR annotation: KAJ7340234.1, Nitrogen permease regulator-like 3 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8VIJ8	GATOR1 complex protein NPRL3 OS=Mus musculus OX=10090 GN=Nprl3 PE=1 SV=1
Q12980	GATOR1 complex protein NPRL3 OS=Homo sapiens OX=9606 GN=NPRL3 PE=1 SV=1
Q9VUB4	GATOR complex protein NPRL3 OS=Drosophila melanogaster OX=7227 GN=Nprl3 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004337 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03666 all species →	NPR3	Nitrogen Permease regulator of amino acid transport activity 3	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005365 all species →	Family	Nitrogen permease regulator 3	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13153 all species →	CGTHBA PROTEIN -14 GENE PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0010508 all species →	Biological Process	positive regulation of autophagy	Interproscan
GO:0032007 all species →	Biological Process	negative regulation of TOR signaling	Interproscan
GO:0034198 all species →	Biological Process	cellular response to amino acid starvation	Interproscan
GO:0038202 all species →	Biological Process	TORC1 signaling	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990130 all species →	Cellular Component	GATOR1 complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20406	NPRL3, NPR3; nitrogen permease regulator 3	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_002966-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

109TPM > 0

7Conditions

13.9Max TPM

6.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	6.65	10.32
polyp at pH7 6	18	18	6.72	9.76
coral polyp · control treatment	16	16	8.66	13.85
coral polyp · oil and dispersant treatment	16	16	5.79	9.43
coral polyp · oil treatment	16	16	7.75	11.95
coral polyp · dispersant treatment	16	16	6.42	12.00
Polyp	10	9	4.03	7.84

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.32
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.03
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.52
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.90
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.57
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.28
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.90
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.49
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.45
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.43
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.21
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.84
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.51
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	5.05
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.74
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.55
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	4.52
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	3.46
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.76
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.69
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.53
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	9.13
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.12
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.35
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.18
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.82
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.66
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	6.37
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.99
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.68
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.56
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.17
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.59
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.56
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.45
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.26
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.85
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.23
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.44
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.21
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.40
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.36
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.59
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	9.58
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.58
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.58
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.51
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.13
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.07
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.98
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.70
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.27
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.43
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.99
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.61
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.13
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.79
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.64
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.06
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.90
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.82
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.87
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.76
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.75
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.34
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.93
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.45
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.12
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.95
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.46
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.63
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.45
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.85
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.82
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.12
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.95
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.84
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.72
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.24
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	6.58
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	5.21
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.12
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	2.38
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	1.65
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.00
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.89
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.53
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.17
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.16
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.90
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.18
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.13
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.53
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.90
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.20
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.79
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	4.76
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.90
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.47
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.30
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	7.84
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	5.82
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	5.24
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	4.44
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	4.16
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	4.07
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	3.91
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	2.70
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	2.13
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.