Gene detail

Detailed information of OS493_005136-T1 in Lophelia pertusa

Genomic Location: scaffold_10:3195777...3201513
NR annotation: KAJ7374786.1, GMP reductase 2 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9P2T1	GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1
Q99L27	GMP reductase 2 OS=Mus musculus OX=10090 GN=Gmpr2 PE=1 SV=2
Q32L93	GMP reductase 2 OS=Bos taurus OX=9913 GN=GMPR2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006261 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00478 all species →	IMPDH	IMP dehydrogenase / GMP reductase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005993 all species →	Family	GMP reductase	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan
IPR050139 all species →	Family	Guanosine monophosphate reductase	Interproscan
IPR015875 all species →	Conserved_site	IMP dehydrogenase / GMP reductase, conserved site	Interproscan
IPR001093 all species →	Domain	IMP dehydrogenase/GMP reductase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43170 all species →	GMP REDUCTASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003920 all species →	Molecular Function	GMP reductase activity	Interproscan
GO:0009117 all species →	Biological Process	nucleotide metabolic process	Interproscan
GO:1902560 all species →	Cellular Component	GMP reductase complex	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00364	guaC, GMPR; GMP reductase	EC:1.7.1.7	Purine metabolism	ko00230	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_005136-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

109TPM > 0

7Conditions

19.0Max TPM

9.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	11.68	19.02
polyp at pH7 6	18	18	10.58	18.64
coral polyp · control treatment	16	16	9.83	14.22
coral polyp · oil and dispersant treatment	16	16	8.45	16.50
coral polyp · oil treatment	16	16	9.85	15.71
coral polyp · dispersant treatment	16	16	9.05	15.69
Polyp	10	9	6.13	12.09

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.02
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.01
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.31
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.68
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.67
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.46
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.08
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.17
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.68
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.93
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	9.48
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.65
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.45
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	8.15
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.08
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.06
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	7.04
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	6.37
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	18.64
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	16.05
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.05
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.66
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	14.24
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.75
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	13.39
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	12.84
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.81
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.44
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.95
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	8.12
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.58
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.42
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	5.49
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	4.04
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.89
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	3.11
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.22
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.20
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.82
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	13.66
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.81
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.45
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.16
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.14
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.12
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.76
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	8.03
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.89
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.45
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.44
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	4.80
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	2.28
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	16.50
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.46
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	11.09
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.77
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.50
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.06
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.49
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.83
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.72
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.62
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.44
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.85
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.81
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.50
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.33
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	2.31
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.71
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.06
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.48
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.66
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.48
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.25
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.64
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.60
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.48
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.48
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.46
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.45
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.61
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.92
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	4.75
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	0.64
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.69
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	14.62
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.04
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.66
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.52
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.26
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.17
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.26
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.74
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.92
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.76
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	6.00
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.91
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.45
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.99
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	0.73
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	12.09
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	8.94
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	8.84
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	8.55
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	6.79
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	4.65
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	4.56
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	3.51
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	3.36
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	0.00

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.