Gene detail

Detailed information of OS493_005831-T1 in Lophelia pertusa

Genomic Location: scaffold_12:1510271...1528343
NR annotation: KAJ7339433.1, hypothetical protein OS493_005831 [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q924L9	Folylpolyglutamate synthase, mitochondrial OS=Cricetulus griseus OX=10029 GN=FPGS PE=2 SV=1
A6H751	Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=FPGS PE=2 SV=1
Q05932	Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002827 (this species only)

Pfam domain

No Pfam domain signature was detected for OS493_005831-T1. This gene does have a gene model — the search simply returned no hit.

InterPro

InterPro term	Type	Description	Source
IPR018109 all species →	Conserved_site	Folylpolyglutamate synthetase, conserved site	Interproscan
IPR036615 all species →	Homologous_superfamily	Mur ligase, C-terminal domain superfamily	Interproscan
IPR036565 all species →	Homologous_superfamily	Mur-like, catalytic domain superfamily	Interproscan
IPR001645 all species →	Family	Folylpolyglutamate synthetase	Interproscan
IPR023600 all species →	Family	Folylpolyglutamate synthase, eukaryota	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11136 all species →	FOLYLPOLYGLUTAMATE SYNTHASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004326 all species →	Molecular Function	tetrahydrofolylpolyglutamate synthase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0009396 all species →	Biological Process	folic acid-containing compound biosynthetic process	Interproscan
GO:0009058 all species →	Biological Process	biosynthetic process	Interproscan
GO:0016881 all species →	Molecular Function	acid-amino acid ligase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0046901 all species →	Biological Process	tetrahydrofolylpolyglutamate biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01930	FPGS; folylpolyglutamate synthase	EC:6.3.2.17	Antifolate resistance	ko01523	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_005831-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

39.0Max TPM

13.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	19.56	39.05
polyp at pH7 6	18	18	17.93	34.17
coral polyp · control treatment	16	16	14.10	36.33
coral polyp · oil and dispersant treatment	16	16	8.06	17.23
coral polyp · oil treatment	16	16	13.16	24.93
coral polyp · dispersant treatment	16	16	10.26	17.54
Polyp	10	10	11.43	19.51

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	39.05
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	37.89
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	31.20
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	28.68
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.71
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	22.18
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.34
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.31
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.20
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.05
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	15.21
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.88
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.28
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	14.06
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	13.27
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	12.58
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.97
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	10.22
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	34.17
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	29.50
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.88
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.04
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.87
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.31
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.23
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.60
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.89
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	15.14
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.63
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	11.55
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.89
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.52
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.48
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.19
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	10.17
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	7.72
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.33
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	18.34
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.37
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.33
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.15
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	17.08
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.59
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	14.21
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.27
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	12.10
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	11.40
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	10.53
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.63
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	7.32
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	6.34
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	5.66
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	17.23
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	13.26
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	12.31
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	10.30
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	9.41
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.83
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.55
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	8.34
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	7.01
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	6.63
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	5.97
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.92
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.71
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	4.33
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.70
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	3.47
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	24.93
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.69
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	18.68
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	16.46
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.31
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.99
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.94
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	12.26
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.96
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.42
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	11.02
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	10.35
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	9.94
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	8.01
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.49
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	7.02
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.54
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.25
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	15.01
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.94
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.72
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.29
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	12.27
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	11.22
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	10.56
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.73
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	8.05
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.83
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	7.58
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.41
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	5.07
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	1.76
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	19.51
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	15.83
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	15.51
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	15.20
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	14.40
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	11.06
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	10.81
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	4.22
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	3.90
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	3.84

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.