Gene detail

Detailed information of OS493_006314-T1 in Lophelia pertusa

Genomic Location: scaffold_13:1914840...1921024
NR annotation: KAJ7393343.1, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [Desmophyllum pertusum]
Species Lophelia pertusa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P0C2X9	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Aldh4a1 PE=1 SV=1
P30038	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3
Q8CHT0	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh4a1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004612 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016160 all species →	Conserved_site	Aldehyde dehydrogenase, cysteine active site	Interproscan
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR029510 all species →	Conserved_site	Aldehyde dehydrogenase, glutamic acid active site	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan
IPR050485 all species →	Family	Proline metabolism enzyme	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42862 all species →	DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan
GO:0003842 all species →	Molecular Function	1-pyrroline-5-carboxylate dehydrogenase activity	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0010133 all species →	Biological Process	proline catabolic process to glutamate	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00294	E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase	EC:1.2.1.88	Arginine and proline metabolism	ko00330	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of OS493_006314-T1 across 110 RNA-seq samples of Lophelia pertusa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

110Samples

110TPM > 0

7Conditions

130.8Max TPM

36.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
polyp at pH7 9	18	18	24.79	42.41
polyp at pH7 6	18	18	26.36	43.53
coral polyp · control treatment	16	16	50.96	130.84
coral polyp · oil and dispersant treatment	16	16	46.00	94.40
coral polyp · oil treatment	16	16	32.06	52.80
coral polyp · dispersant treatment	16	16	49.54	91.93
Polyp	10	10	22.21	35.66

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11359522	polyp at pH7 9	not recorded	not recorded	not recorded	-	42.41
SRR11359519	polyp at pH7 9	not recorded	not recorded	not recorded	-	37.06
SRR11359523	polyp at pH7 9	not recorded	not recorded	not recorded	-	35.67
SRR11359498	polyp at pH7 9	not recorded	not recorded	not recorded	-	32.59
SRR11359521	polyp at pH7 9	not recorded	not recorded	not recorded	-	30.10
SRR11359518	polyp at pH7 9	not recorded	not recorded	not recorded	-	29.72
SRR11359499	polyp at pH7 9	not recorded	not recorded	not recorded	-	27.91
SRR11359520	polyp at pH7 9	not recorded	not recorded	not recorded	-	26.91
SRR11359510	polyp at pH7 9	not recorded	not recorded	not recorded	-	21.11
SRR11359494	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.78
SRR11359507	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.71
SRR11359511	polyp at pH7 9	not recorded	not recorded	not recorded	-	19.14
SRR11359509	polyp at pH7 9	not recorded	not recorded	not recorded	-	18.52
SRR11359496	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.58
SRR11359508	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.30
SRR11359495	polyp at pH7 9	not recorded	not recorded	not recorded	-	17.22
SRR11359506	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.83
SRR11359497	polyp at pH7 9	not recorded	not recorded	not recorded	-	16.72
SRR11359529	polyp at pH7 6	not recorded	not recorded	not recorded	-	43.53
SRR11359528	polyp at pH7 6	not recorded	not recorded	not recorded	-	40.24
SRR11359526	polyp at pH7 6	not recorded	not recorded	not recorded	-	33.46
SRR11359527	polyp at pH7 6	not recorded	not recorded	not recorded	-	31.08
SRR11359504	polyp at pH7 6	not recorded	not recorded	not recorded	-	29.47
SRR11359505	polyp at pH7 6	not recorded	not recorded	not recorded	-	29.00
SRR11359524	polyp at pH7 6	not recorded	not recorded	not recorded	-	26.83
SRR11359525	polyp at pH7 6	not recorded	not recorded	not recorded	-	25.34
SRR11359515	polyp at pH7 6	not recorded	not recorded	not recorded	-	24.28
SRR11359501	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.87
SRR11359516	polyp at pH7 6	not recorded	not recorded	not recorded	-	23.18
SRR11359500	polyp at pH7 6	not recorded	not recorded	not recorded	-	22.94
SRR11359517	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.93
SRR11359514	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.64
SRR11359513	polyp at pH7 6	not recorded	not recorded	not recorded	-	21.06
SRR11359502	polyp at pH7 6	not recorded	not recorded	not recorded	-	20.03
SRR11359503	polyp at pH7 6	not recorded	not recorded	not recorded	-	19.31
SRR11359512	polyp at pH7 6	not recorded	not recorded	not recorded	-	17.30
SRR16705973	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	130.84
SRR16705990	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	69.86
SRR16705972	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	69.18
SRR16705957	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	68.46
SRR16705960	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	64.87
SRR16705991	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	56.65
SRR16705965	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	53.69
SRR16705946	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	50.66
SRR16705974	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	39.00
SRR16705989	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	38.19
SRR16705971	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	36.79
SRR16705942	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	35.82
SRR16705970	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.71
SRR16705943	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	28.51
SRR16705975	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	23.08
SRR16705992	coral polyp · control treatment	coral polyp	polyp	control treatment	SRP344271	21.02
SRR16705977	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	94.40
SRR16705995	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	66.78
SRR16705944	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	61.50
SRR16705997	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	54.53
SRR16706004	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	50.68
SRR16706005	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	49.29
SRR16705979	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	48.90
SRR16705947	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	47.50
SRR16705945	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	47.28
SRR16705994	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	42.88
SRR16705976	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.55
SRR16705996	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	34.37
SRR16705978	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	33.35
SRR16705993	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	27.77
SRR16705948	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	21.74
SRR16705982	coral polyp · oil and dispersant treatment	coral polyp	polyp	oil and dispersant treatment	SRP344271	20.40
SRR16705980	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	52.80
SRR16706001	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	47.54
SRR16706000	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	45.98
SRR16705949	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	45.21
SRR16705999	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	44.99
SRR16705981	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	44.20
SRR16705961	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	42.37
SRR16705952	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	28.73
SRR16705983	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	28.01
SRR16705984	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	25.55
SRR16705998	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	23.99
SRR16705951	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	21.48
SRR16705962	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	19.71
SRR16705950	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	15.20
SRR16705963	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	14.14
SRR16705964	coral polyp · oil treatment	coral polyp	polyp	oil treatment	SRP344271	13.02
SRR16705966	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	91.93
SRR16705958	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	85.41
SRR16706003	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	80.54
SRR16705968	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	69.51
SRR16705953	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	63.04
SRR16705988	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	62.31
SRR16705955	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	47.48
SRR16705954	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	43.81
SRR16705969	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	42.60
SRR16705967	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	41.08
SRR16706002	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	35.26
SRR16705959	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	34.17
SRR16705987	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	34.05
SRR16705986	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	30.09
SRR16705956	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	17.64
SRR16705985	coral polyp · dispersant treatment	coral polyp	polyp	dispersant treatment	SRP344271	13.71
SRR23025711	Polyp	not recorded	not recorded	not recorded	-	35.66
SRR23025713	Polyp	not recorded	not recorded	not recorded	-	31.38
SRR23025710	Polyp	not recorded	not recorded	not recorded	-	31.36
SRR7746668	Polyp	not recorded	not recorded	not recorded	-	29.83
SRR23025712	Polyp	not recorded	not recorded	not recorded	-	22.25
SRR23025708	Polyp	not recorded	not recorded	not recorded	-	21.33
SRR7746667	Polyp	not recorded	not recorded	not recorded	-	18.97
SRR23025709	Polyp	not recorded	not recorded	not recorded	-	14.95
SRR7746669	Polyp	not recorded	not recorded	not recorded	-	8.34
SRR7746666	Polyp	not recorded	not recorded	not recorded	-	8.02

Source: CnidoSite RNA-seq expression matrices (LPERT_TPM, StringTie quantification over 110 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.